ENSG00000125952

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000358402 ENSG00000125952 No_inf pgKDN_inf MAX protein_coding protein_coding 42.31002 43.13108 45.50633 1.522196 2.893282 0.0773218 34.074955 35.34128 35.79414 1.496891 2.056424 0.01836363 0.80597500 0.819475 0.787850 -0.031625 0.82515381 0.02737684 FALSE  
ENST00000358664 ENSG00000125952 No_inf pgKDN_inf MAX protein_coding protein_coding 42.31002 43.13108 45.50633 1.522196 2.893282 0.0773218 2.450513 0.00000 3.92288 0.000000 1.490555 8.61944219 0.06100833 0.000000 0.091525 0.091525 0.02737684 0.02737684 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000125952 E001 0.0000000       14 65006174 65006284 111 -      
ENSG00000125952 E002 0.2537694 0.0160576097 0.267252305   14 65060918 65062002 1085 - 0.000 0.168 10.709
ENSG00000125952 E003 0.1268540 0.0122196252 0.577230125   14 65065537 65065602 66 - 0.000 0.092 11.479
ENSG00000125952 E004 0.1170040 0.0116289603 0.502069577   14 65069694 65070369 676 - 0.098 0.000 -12.358
ENSG00000125952 E005 0.1268540 0.0122196252 0.577230125   14 65075124 65075126 3 - 0.000 0.092 11.479
ENSG00000125952 E006 3.4749139 0.0045560102 0.087549035 0.30667466 14 65075127 65075157 31 - 0.515 0.740 0.983
ENSG00000125952 E007 9.5729889 0.0043906768 0.890246801 0.96333574 14 65075158 65075201 44 - 1.015 1.030 0.053
ENSG00000125952 E008 192.9820048 0.0001415967 0.105623048 0.34005930 14 65075202 65076085 884 - 2.271 2.300 0.096
ENSG00000125952 E009 80.0582527 0.0007283406 0.021439041 0.13257203 14 65076086 65076457 372 - 1.945 1.873 -0.241
ENSG00000125952 E010 16.5005592 0.0008553111 0.399852226 0.68353168 14 65076458 65076461 4 - 1.272 1.215 -0.202
ENSG00000125952 E011 44.2765462 0.0003355260 0.176892574 0.45128064 14 65076462 65076608 147 - 1.684 1.628 -0.191
ENSG00000125952 E012 24.0719669 0.0065704986 0.246561005 0.53716357 14 65076609 65076663 55 - 1.436 1.362 -0.257
ENSG00000125952 E013 4.9225133 0.0113943004 0.482107627 0.74704911 14 65076664 65077192 529 - 0.724 0.809 0.341
ENSG00000125952 E014 1.8599980 0.0183960986 0.257152735 0.54945233 14 65077193 65077286 94 - 0.355 0.527 0.904
ENSG00000125952 E015 0.3804973 0.0158121442 0.117444978   14 65077287 65077300 14 - 0.000 0.233 12.962
ENSG00000125952 E016 0.3808443 0.0191425591 0.118419291   14 65077301 65077327 27 - 0.000 0.233 12.948
ENSG00000125952 E017 1.1065895 0.0104038242 0.821835326 0.93540724 14 65077328 65077343 16 - 0.304 0.339 0.226
ENSG00000125952 E018 1.6133115 0.0085592195 0.206467250 0.49012175 14 65077344 65077384 41 - 0.304 0.496 1.074
ENSG00000125952 E019 1.6146637 0.0122595076 0.209170447 0.49341318 14 65077385 65077428 44 - 0.304 0.496 1.074
ENSG00000125952 E020 0.9886765 0.0124398606 0.546025168 0.79187724 14 65077429 65077562 134 - 0.245 0.339 0.641
ENSG00000125952 E021 0.9609790 0.0116072989 0.126463214 0.37690442 14 65077563 65077643 81 - 0.401 0.168 -1.680
ENSG00000125952 E022 2.2406855 0.0065931541 0.080285207 0.29086822 14 65077644 65077773 130 - 0.355 0.610 1.283
ENSG00000125952 E023 2.1410561 0.0066951275 0.001455689 0.01997739 14 65077774 65077912 139 - 0.178 0.658 2.811
ENSG00000125952 E024 23.4062919 0.0005846581 0.900215812 0.96758472 14 65077913 65078036 124 - 1.390 1.384 -0.020
ENSG00000125952 E025 4.2018832 0.0459593596 0.329354451 0.62172843 14 65083744 65084299 556 - 0.632 0.776 0.596
ENSG00000125952 E026 0.2454921 0.0161939021 0.955840078   14 65093498 65093702 205 - 0.098 0.092 -0.096
ENSG00000125952 E027 0.0000000       14 65093703 65093707 5 -      
ENSG00000125952 E028 0.0000000       14 65093708 65093815 108 -      
ENSG00000125952 E029 1.7297164 0.0079693345 0.349640521 0.63993185 14 65101546 65101572 27 - 0.355 0.496 0.753
ENSG00000125952 E030 0.0000000       14 65101573 65101685 113 -      
ENSG00000125952 E031 20.1951134 0.0011555030 0.711683319 0.88347977 14 65102304 65102508 205 - 1.337 1.315 -0.078
ENSG00000125952 E032 0.8630785 0.0127790358 0.779259938 0.91499838 14 65102509 65102695 187 - 0.245 0.289 0.319

Help

Please Click HERE to learn more details about the results from DEXseq.