ENSG00000126107

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000372168 ENSG00000126107 No_inf pgKDN_inf HECTD3 protein_coding protein_coding 23.70764 29.07612 19.35577 1.939948 1.361071 -0.5868221 4.1832837 4.7617023 3.5759137 1.3887858 1.3677788 -0.4121633 0.17718333 0.163800 0.172900 0.009100 1.00000000 0.03937953 FALSE TRUE
ENST00000372172 ENSG00000126107 No_inf pgKDN_inf HECTD3 protein_coding protein_coding 23.70764 29.07612 19.35577 1.939948 1.361071 -0.5868221 9.7920870 7.8042640 10.8661250 2.7258219 1.5574693 0.4769827 0.44004167 0.268075 0.581725 0.313650 0.49047759 0.03937953 FALSE TRUE
ENST00000486132 ENSG00000126107 No_inf pgKDN_inf HECTD3 protein_coding protein_coding_CDS_not_defined 23.70764 29.07612 19.35577 1.939948 1.361071 -0.5868221 3.4713291 6.8842356 1.1937754 0.8463565 0.4245738 -2.5178244 0.13231667 0.236450 0.058075 -0.178375 0.03937953 0.03937953 FALSE TRUE
ENST00000487488 ENSG00000126107 No_inf pgKDN_inf HECTD3 protein_coding protein_coding_CDS_not_defined 23.70764 29.07612 19.35577 1.939948 1.361071 -0.5868221 2.3347932 4.8996098 0.8100298 1.4756034 0.5895914 -2.5818601 0.08569167 0.162275 0.036875 -0.125400 0.23535414 0.03937953 FALSE TRUE
MSTRG.904.1 ENSG00000126107 No_inf pgKDN_inf HECTD3 protein_coding   23.70764 29.07612 19.35577 1.939948 1.361071 -0.5868221 1.6319909 2.4831217 0.5262221 2.4831217 0.5262221 -2.2170507 0.07135000 0.094650 0.032650 -0.062000 0.99134863 0.03937953 TRUE TRUE
MSTRG.904.2 ENSG00000126107 No_inf pgKDN_inf HECTD3 protein_coding   23.70764 29.07612 19.35577 1.939948 1.361071 -0.5868221 0.6783285 0.2600948 1.7748909 0.1682459 1.7748909 2.7242983 0.03308333 0.009425 0.089825 0.080400 1.00000000 0.03937953 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000126107 E001 0.0000000       1 45002540 45002547 8 -      
ENSG00000126107 E002 123.0583765 0.0002134676 7.807492e-01 9.155417e-01 1 45002548 45003576 1029 - 2.080 2.091 0.037
ENSG00000126107 E003 16.8429404 0.0102073859 1.338393e-01 3.887708e-01 1 45003669 45003740 72 - 1.166 1.291 0.442
ENSG00000126107 E004 21.6533916 0.0006583609 1.175116e-01 3.621227e-01 1 45003855 45003936 82 - 1.283 1.387 0.362
ENSG00000126107 E005 23.5551504 0.0006153479 6.748786e-01 8.652809e-01 1 45004060 45004134 75 - 1.365 1.395 0.102
ENSG00000126107 E006 27.0720254 0.0009925189 1.797051e-01 4.549573e-01 1 45004248 45004377 130 - 1.391 1.472 0.280
ENSG00000126107 E007 39.4969834 0.0004465741 4.779248e-01 7.440396e-01 1 45004600 45004806 207 - 1.617 1.588 -0.098
ENSG00000126107 E008 11.0634525 0.0098072788 2.137825e-07 1.153014e-05 1 45004807 45005588 782 - 0.672 1.225 2.096
ENSG00000126107 E009 2.6318193 0.1489820424 9.218343e-02 3.153308e-01 1 45005645 45005793 149 - 0.330 0.661 1.654
ENSG00000126107 E010 18.4640949 0.0008628289 6.762096e-01 8.658391e-01 1 45005794 45005883 90 - 1.296 1.272 -0.084
ENSG00000126107 E011 3.2920860 0.0200084670 1.390020e-05 4.544876e-04 1 45005884 45005996 113 - 0.109 0.797 4.212
ENSG00000126107 E012 12.8307896 0.0118315249 7.321656e-01 8.935875e-01 1 45005997 45006072 76 - 1.112 1.148 0.129
ENSG00000126107 E013 7.7160303 0.0142282069 3.150401e-01 6.078769e-01 1 45006073 45006116 44 - 0.992 0.889 -0.387
ENSG00000126107 E014 0.2543986 0.0160461368 3.677999e-01   1 45006117 45006224 108 - 0.000 0.153 9.619
ENSG00000126107 E015 15.4575515 0.0009944462 1.683603e-01 4.395346e-01 1 45006692 45006795 104 - 1.264 1.167 -0.341
ENSG00000126107 E016 10.9789597 0.0013269036 1.184188e-02 8.976600e-02 1 45006951 45007015 65 - 1.182 0.974 -0.754
ENSG00000126107 E017 0.0000000       1 45007016 45007116 101 -      
ENSG00000126107 E018 9.3505543 0.0134084096 2.699004e-03 3.187389e-02 1 45007219 45007271 53 - 1.157 0.865 -1.080
ENSG00000126107 E019 17.4387017 0.0030408642 1.491535e-03 2.038633e-02 1 45007413 45007595 183 - 1.376 1.155 -0.777
ENSG00000126107 E020 12.0842670 0.0013653403 7.636931e-01 9.078471e-01 1 45008240 45008321 82 - 1.092 1.121 0.104
ENSG00000126107 E021 2.4044860 0.1697099984 5.050438e-03 4.998904e-02 1 45008322 45008535 214 - 0.109 0.681 3.738
ENSG00000126107 E022 20.1711378 0.0202258670 1.777871e-01 4.524925e-01 1 45008536 45008701 166 - 1.243 1.364 0.424
ENSG00000126107 E023 15.2797976 0.0010120037 7.889946e-01 9.189841e-01 1 45009144 45009226 83 - 1.190 1.214 0.085
ENSG00000126107 E024 16.2345167 0.0008423082 7.055206e-01 8.803882e-01 1 45009369 45009482 114 - 1.243 1.220 -0.081
ENSG00000126107 E025 13.8337980 0.0011338913 8.297952e-02 2.968768e-01 1 45009568 45009683 116 - 1.236 1.107 -0.458
ENSG00000126107 E026 13.9450222 0.0243541844 1.722074e-01 4.448410e-01 1 45009986 45010121 136 - 1.243 1.107 -0.483
ENSG00000126107 E027 0.6270921 0.0147839500 3.034298e-01 5.967847e-01 1 45010122 45010200 79 - 0.109 0.265 1.568
ENSG00000126107 E028 9.9646743 0.0119168772 8.804122e-01 9.597411e-01 1 45010201 45010293 93 - 1.039 1.029 -0.038
ENSG00000126107 E029 8.8052316 0.0037636790 1.296042e-01 3.818915e-01 1 45010546 45010706 161 - 1.061 0.923 -0.513
ENSG00000126107 E030 1.9240696 0.0076841689 8.791775e-03 7.373498e-02 1 45010889 45011324 436 - 0.645 0.265 -2.017

Help

Please Click HERE to learn more details about the results from DEXseq.