ENSG00000126216

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000261965 ENSG00000126216 No_inf pgKDN_inf TUBGCP3 protein_coding protein_coding 17.60099 17.671 15.01101 2.375831 0.5412332 -0.2352187 8.7655861 5.133560 11.94387 2.1954459 0.4283253 1.21663882 0.53447500 0.339050 0.79610 0.457050 0.21660220 0.01212109 FALSE TRUE
ENST00000464139 ENSG00000126216 No_inf pgKDN_inf TUBGCP3 protein_coding protein_coding 17.60099 17.671 15.01101 2.375831 0.5412332 -0.2352187 2.2128111 2.277306 2.17319 0.1926525 0.0910488 -0.06721154 0.13096667 0.140525 0.14505 0.004525 0.98366443 0.01212109 FALSE TRUE
ENST00000469302 ENSG00000126216 No_inf pgKDN_inf TUBGCP3 protein_coding protein_coding_CDS_not_defined 17.60099 17.671 15.01101 2.375831 0.5412332 -0.2352187 4.2858770 5.268996 0.00000 2.0214332 0.0000000 -9.04411984 0.21075833 0.261225 0.00000 -0.261225 0.01212109 0.01212109   FALSE
MSTRG.8085.3 ENSG00000126216 No_inf pgKDN_inf TUBGCP3 protein_coding   17.60099 17.671 15.01101 2.375831 0.5412332 -0.2352187 0.6820554 2.046166 0.00000 2.0461662 0.0000000 -7.68381306 0.03392500 0.101775 0.00000 -0.101775 0.86250755 0.01212109 FALSE TRUE
MSTRG.8085.4 ENSG00000126216 No_inf pgKDN_inf TUBGCP3 protein_coding   17.60099 17.671 15.01101 2.375831 0.5412332 -0.2352187 0.4379596 1.313879 0.00000 1.3138788 0.0000000 -7.04862720 0.02510833 0.075325 0.00000 -0.075325 0.86621401 0.01212109 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000126216 E001 0.3627784 0.0168138246 0.67180387   13 112485011 112485032 22 - 0.163 0.101 -0.793
ENSG00000126216 E002 0.3627784 0.0168138246 0.67180387   13 112485033 112485040 8 - 0.163 0.101 -0.793
ENSG00000126216 E003 1.5597740 0.0084856743 0.08243342 0.29568796 13 112485041 112485076 36 - 0.516 0.253 -1.530
ENSG00000126216 E004 60.6426262 0.0003157419 0.55113579 0.79504006 13 112485077 112485843 767 - 1.778 1.802 0.079
ENSG00000126216 E005 14.2627674 0.0009687525 0.06080599 0.24749154 13 112485844 112486151 308 - 1.109 1.251 0.507
ENSG00000126216 E006 14.5108271 0.0148735462 0.07661965 0.28300569 13 112489581 112489697 117 - 1.109 1.264 0.551
ENSG00000126216 E007 0.0000000       13 112489698 112489823 126 -      
ENSG00000126216 E008 0.5085150 0.0158611668 0.03240579 0.17051452 13 112498807 112498936 130 - 0.000 0.312 11.949
ENSG00000126216 E009 12.6183778 0.0169500639 0.49874642 0.75911922 13 112499045 112499185 141 - 1.101 1.167 0.235
ENSG00000126216 E010 12.0921494 0.0023062020 0.98562351 0.99905314 13 112504032 112504163 132 - 1.116 1.117 0.003
ENSG00000126216 E011 10.1585035 0.0014513044 0.60540231 0.82803156 13 112504626 112504714 89 - 1.024 1.071 0.173
ENSG00000126216 E012 13.3471134 0.0011737205 0.41246353 0.69375063 13 112516440 112516575 136 - 1.124 1.189 0.234
ENSG00000126216 E013 6.7357684 0.0224571359 0.57381697 0.80901982 13 112518975 112519043 69 - 0.854 0.922 0.260
ENSG00000126216 E014 9.5682810 0.0024506052 0.04717222 0.21334895 13 112519886 112520021 136 - 1.101 0.922 -0.658
ENSG00000126216 E015 0.3724075 0.0164938378 0.50213684   13 112521663 112521864 202 - 0.089 0.184 1.207
ENSG00000126216 E016 14.6629463 0.0012384908 0.02231427 0.13586565 13 112522320 112522509 190 - 1.268 1.099 -0.600
ENSG00000126216 E017 8.8971442 0.0015987762 0.63783441 0.84546638 13 112526942 112527050 109 - 1.014 0.974 -0.150
ENSG00000126216 E018 9.2832773 0.0207832789 0.94282522 0.98412031 13 112527374 112527484 111 - 1.015 1.009 -0.021
ENSG00000126216 E019 3.4564739 0.0177736349 0.15753113 0.42413557 13 112544556 112545698 1143 - 0.545 0.738 0.835
ENSG00000126216 E020 12.5453402 0.0428376802 0.50945360 0.76733336 13 112545699 112545861 163 - 1.166 1.090 -0.273
ENSG00000126216 E021 2.6967472 0.1549606290 0.75652838 0.90416473 13 112545862 112545865 4 - 0.545 0.590 0.208
ENSG00000126216 E022 1.2443924 0.4469776995 0.52177384 0.77553571 13 112545866 112546203 338 - 0.226 0.454 1.431
ENSG00000126216 E023 18.5859325 0.0009236396 0.00946507 0.07760552 13 112546482 112547619 1138 - 1.199 1.373 0.611
ENSG00000126216 E024 11.6994906 0.0040909636 0.46280624 0.73298987 13 112547620 112547752 133 - 1.131 1.071 -0.217
ENSG00000126216 E025 8.7755168 0.0015638554 0.54898269 0.79376450 13 112548108 112548176 69 - 1.014 0.962 -0.196
ENSG00000126216 E026 11.6954007 0.0013957512 0.44422303 0.71889834 13 112554057 112554182 126 - 1.131 1.071 -0.216
ENSG00000126216 E027 8.0526388 0.0018025767 0.85531206 0.94910977 13 112554887 112555005 119 - 0.964 0.949 -0.056
ENSG00000126216 E028 7.9203313 0.0252601225 0.61786048 0.83459706 13 112556052 112556224 173 - 0.974 0.922 -0.194
ENSG00000126216 E029 10.5997172 0.0148693132 0.49382347 0.75561380 13 112558196 112558413 218 - 1.093 1.031 -0.227
ENSG00000126216 E030 4.3572378 0.0035534189 0.10989863 0.34800803 13 112559322 112559399 78 - 0.811 0.619 -0.793
ENSG00000126216 E031 5.1890005 0.0030436286 0.02990448 0.16263670 13 112565111 112565178 68 - 0.894 0.645 -0.999
ENSG00000126216 E032 6.1965275 0.0023682525 0.29137543 0.58492402 13 112569152 112569259 108 - 0.906 0.797 -0.425
ENSG00000126216 E033 0.1272623 0.0123459538 0.46895150   13 112584039 112584161 123 - 0.000 0.101 10.117
ENSG00000126216 E034 0.1265070 0.0123281009 0.46890911   13 112587230 112587346 117 - 0.000 0.101 10.117
ENSG00000126216 E035 4.7415801 0.0043957239 0.49143838 0.75373916 13 112587905 112588205 301 - 0.795 0.717 -0.316

Help

Please Click HERE to learn more details about the results from DEXseq.