ENSG00000126456

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000309877 ENSG00000126456 No_inf pgKDN_inf IRF3 protein_coding protein_coding 76.53104 77.04874 70.1543 6.1647 4.653315 -0.1352214 4.991698 5.995172 3.377940 2.1341235 1.3146529 -0.8257972 0.06384167 0.077950 0.046125 -0.031825 0.90568422 0.02613738 FALSE  
ENST00000377135 ENSG00000126456 No_inf pgKDN_inf IRF3 protein_coding protein_coding 76.53104 77.04874 70.1543 6.1647 4.653315 -0.1352214 3.342507 5.252931 0.000000 3.0778909 0.0000000 -9.0397226 0.03865000 0.060075 0.000000 -0.060075 0.47134823 0.02613738 FALSE  
ENST00000377139 ENSG00000126456 No_inf pgKDN_inf IRF3 protein_coding protein_coding 76.53104 77.04874 70.1543 6.1647 4.653315 -0.1352214 6.153260 5.184656 9.817880 5.1846556 5.8254958 0.9198522 0.09177500 0.076175 0.153925 0.077750 0.84205413 0.02613738 FALSE  
ENST00000597369 ENSG00000126456 No_inf pgKDN_inf IRF3 protein_coding retained_intron 76.53104 77.04874 70.1543 6.1647 4.653315 -0.1352214 6.525608 10.722585 4.354957 2.1354321 0.8692873 -1.2979581 0.08390000 0.135650 0.062125 -0.073525 0.24892726 0.02613738    
ENST00000597636 ENSG00000126456 No_inf pgKDN_inf IRF3 protein_coding nonsense_mediated_decay 76.53104 77.04874 70.1543 6.1647 4.653315 -0.1352214 4.617236 8.173233 2.459724 1.3240073 1.1642556 -1.7283212 0.06004167 0.105800 0.036200 -0.069600 0.33953940 0.02613738 TRUE  
ENST00000599144 ENSG00000126456 No_inf pgKDN_inf IRF3 protein_coding protein_coding 76.53104 77.04874 70.1543 6.1647 4.653315 -0.1352214 2.905670 0.000000 5.917673 0.0000000 3.7989083 9.2113220 0.03905833 0.000000 0.083650 0.083650 0.02613738 0.02613738 FALSE  
ENST00000601291 ENSG00000126456 No_inf pgKDN_inf IRF3 protein_coding protein_coding 76.53104 77.04874 70.1543 6.1647 4.653315 -0.1352214 4.533714 2.042951 6.296474 1.0652537 0.8379472 1.6191343 0.06016667 0.025375 0.089450 0.064075 0.23415213 0.02613738 FALSE  
MSTRG.15468.10 ENSG00000126456 No_inf pgKDN_inf IRF3 protein_coding   76.53104 77.04874 70.1543 6.1647 4.653315 -0.1352214 6.719334 10.892046 5.284410 1.4789693 1.9256269 -1.0420570 0.08818333 0.143500 0.072900 -0.070600 0.64168483 0.02613738 FALSE  
MSTRG.15468.13 ENSG00000126456 No_inf pgKDN_inf IRF3 protein_coding   76.53104 77.04874 70.1543 6.1647 4.653315 -0.1352214 6.837173 10.868189 3.832385 0.4138711 0.7108544 -1.5013643 0.09002500 0.143625 0.054400 -0.089225 0.06344745 0.02613738 TRUE  
MSTRG.15468.3 ENSG00000126456 No_inf pgKDN_inf IRF3 protein_coding   76.53104 77.04874 70.1543 6.1647 4.653315 -0.1352214 7.640172 1.168831 7.906873 1.1688313 2.6036851 2.7475735 0.09699167 0.018025 0.107225 0.089200 0.03600709 0.02613738 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000126456 E001 0.0000000       19 49659569 49659569 1 -      
ENSG00000126456 E002 0.0000000       19 49659570 49659571 2 -      
ENSG00000126456 E003 0.0000000       19 49659572 49659572 1 -      
ENSG00000126456 E004 0.0000000       19 49659573 49659574 2 -      
ENSG00000126456 E005 0.0000000       19 49659575 49659576 2 -      
ENSG00000126456 E006 3.0569321 0.0048763817 3.047612e-01 5.980835e-01 19 49659577 49659578 2 - 0.678 0.542 -0.601
ENSG00000126456 E007 9.5694539 0.0196555708 3.836568e-01 6.697572e-01 19 49659579 49659631 53 - 1.069 0.977 -0.337
ENSG00000126456 E008 41.2494832 0.0043689645 1.212672e-01 3.686353e-01 19 49659632 49659757 126 - 1.664 1.582 -0.279
ENSG00000126456 E009 38.7116912 0.0066533501 3.554282e-02 1.805733e-01 19 49659758 49659833 76 - 1.659 1.538 -0.412
ENSG00000126456 E010 53.2583346 0.0002841053 2.906862e-02 1.599293e-01 19 49660713 49660828 116 - 1.777 1.688 -0.299
ENSG00000126456 E011 5.1679329 0.0027326890 8.762829e-01 9.580621e-01 19 49660829 49660844 16 - 0.793 0.776 -0.071
ENSG00000126456 E012 3.9778009 0.0039286204 1.164408e-01 3.598921e-01 19 49660845 49661045 201 - 0.557 0.760 0.868
ENSG00000126456 E013 21.4461578 0.0006401412 5.005066e-06 1.886396e-04 19 49661046 49661449 404 - 1.129 1.442 1.099
ENSG00000126456 E014 15.5286988 0.0093759374 6.998792e-07 3.388446e-05 19 49661450 49661594 145 - 0.884 1.340 1.649
ENSG00000126456 E015 7.0360055 0.0109168103 2.638798e-05 7.780580e-04 19 49661595 49661625 31 - 0.521 1.039 2.099
ENSG00000126456 E016 28.0988132 0.0004880002 4.551582e-09 3.428562e-07 19 49661626 49661947 322 - 1.206 1.566 1.249
ENSG00000126456 E017 65.5640776 0.0002457991 9.548322e-01 9.889918e-01 19 49661948 49662068 121 - 1.813 1.815 0.007
ENSG00000126456 E018 34.2919621 0.0070162845 1.335367e-02 9.698581e-02 19 49662069 49662132 64 - 1.622 1.474 -0.506
ENSG00000126456 E019 34.0615325 0.0009621493 5.681956e-03 5.427363e-02 19 49662133 49662174 42 - 1.616 1.474 -0.486
ENSG00000126456 E020 39.2756976 0.0003646354 4.434302e-02 2.058527e-01 19 49662175 49662238 64 - 1.651 1.556 -0.323
ENSG00000126456 E021 37.8948053 0.0029271713 4.715827e-01 7.389622e-01 19 49662239 49662300 62 - 1.603 1.566 -0.128
ENSG00000126456 E022 34.0185239 0.0007015685 9.039182e-01 9.690691e-01 19 49662301 49662328 28 - 1.532 1.538 0.021
ENSG00000126456 E023 0.4901058 0.0158566150 7.390197e-01   19 49662329 49662329 1 - 0.198 0.150 -0.486
ENSG00000126456 E024 1.5975460 0.1486711093 7.362491e-01 8.953403e-01 19 49662375 49662424 50 - 0.437 0.389 -0.263
ENSG00000126456 E025 23.7905697 0.0005835213 8.368120e-01 9.415182e-01 19 49662425 49662426 2 - 1.378 1.391 0.044
ENSG00000126456 E026 31.0614378 0.0004610031 8.996900e-01 9.673241e-01 19 49662427 49662453 27 - 1.493 1.500 0.023
ENSG00000126456 E027 48.1295710 0.0002968192 5.958066e-01 8.222680e-01 19 49662454 49662538 85 - 1.696 1.673 -0.077
ENSG00000126456 E028 34.4013055 0.0004281139 2.085502e-01 4.926180e-01 19 49662539 49662584 46 - 1.577 1.514 -0.217
ENSG00000126456 E029 20.3090453 0.0008717359 7.223970e-01 8.884223e-01 19 49662585 49662592 8 - 1.334 1.311 -0.081
ENSG00000126456 E030 25.9592862 0.0080645467 6.245956e-01 8.385050e-01 19 49662593 49662617 25 - 1.442 1.408 -0.114
ENSG00000126456 E031 37.0999075 0.0060929683 8.827759e-01 9.605607e-01 19 49663188 49663235 48 - 1.567 1.575 0.028
ENSG00000126456 E032 30.4861390 0.0047620585 4.884685e-01 7.517495e-01 19 49663236 49663258 23 - 1.464 1.506 0.143
ENSG00000126456 E033 3.2355260 0.0044499808 1.220539e-01 3.695715e-01 19 49663259 49663342 84 - 0.481 0.693 0.955
ENSG00000126456 E034 29.2845153 0.0015059905 5.342618e-01 7.843982e-01 19 49663343 49663372 30 - 1.493 1.458 -0.120
ENSG00000126456 E035 36.9134820 0.0004286522 5.556255e-01 7.980163e-01 19 49663373 49663420 48 - 1.587 1.558 -0.099
ENSG00000126456 E036 44.6273073 0.0004609693 2.495240e-01 5.404750e-01 19 49663421 49663514 94 - 1.681 1.629 -0.174
ENSG00000126456 E037 12.0006026 0.0272894061 6.550009e-04 1.076258e-02 19 49663515 49663869 355 - 0.832 1.223 1.440
ENSG00000126456 E038 2.1381933 0.0950219718 2.183352e-02 1.341348e-01 19 49664443 49664552 110 - 0.198 0.613 2.421
ENSG00000126456 E039 5.6489492 0.0066728896 5.957046e-01 8.222680e-01 19 49664553 49664586 34 - 0.850 0.790 -0.234
ENSG00000126456 E040 8.4941609 0.0020974783 9.508339e-01 9.875356e-01 19 49664587 49664673 87 - 0.973 0.967 -0.022
ENSG00000126456 E041 45.1880391 0.0004426124 8.232125e-01 9.357038e-01 19 49664674 49664846 173 - 1.662 1.652 -0.034
ENSG00000126456 E042 16.9852183 0.0008278885 3.471933e-02 1.780729e-01 19 49664847 49664950 104 - 1.147 1.302 0.546
ENSG00000126456 E043 12.4648063 0.0013010972 5.487477e-04 9.389643e-03 19 49664951 49665458 508 - 0.916 1.218 1.099
ENSG00000126456 E044 0.0000000       19 49665459 49665483 25 -      
ENSG00000126456 E045 0.0000000       19 49665484 49665630 147 -      
ENSG00000126456 E046 0.0000000       19 49665631 49665634 4 -      
ENSG00000126456 E047 0.0000000       19 49665635 49665671 37 -      
ENSG00000126456 E048 0.0000000       19 49665672 49665875 204 -      

Help

Please Click HERE to learn more details about the results from DEXseq.