ENSG00000126561

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000468096 ENSG00000126561 No_inf pgKDN_inf STAT5A protein_coding retained_intron 17.92534 9.917721 17.88198 0.6881333 0.9319237 0.849779 6.6137395 4.553531 5.7659236 0.53960230 0.6894452 0.3399010 0.38181667 0.460925 0.323475 -0.137450 0.66808265 0.04508066 FALSE  
ENST00000479417 ENSG00000126561 No_inf pgKDN_inf STAT5A protein_coding retained_intron 17.92534 9.917721 17.88198 0.6881333 0.9319237 0.849779 0.9450908 1.062914 0.0000000 0.52073683 0.0000000 -6.7453905 0.05291667 0.098025 0.000000 -0.098025 0.04508066 0.04508066 FALSE  
ENST00000587646 ENSG00000126561 No_inf pgKDN_inf STAT5A protein_coding retained_intron 17.92534 9.917721 17.88198 0.6881333 0.9319237 0.849779 1.0515759 1.043060 0.6239236 0.05243244 0.1288134 -0.7322072 0.06733333 0.106800 0.035125 -0.071675 0.38257123 0.04508066 FALSE  
ENST00000588868 ENSG00000126561 No_inf pgKDN_inf STAT5A protein_coding protein_coding 17.92534 9.917721 17.88198 0.6881333 0.9319237 0.849779 0.9538029 1.017047 0.0000000 1.01704740 0.0000000 -6.6823590 0.06171667 0.111575 0.000000 -0.111575 0.82590749 0.04508066 FALSE  
ENST00000590726 ENSG00000126561 No_inf pgKDN_inf STAT5A protein_coding protein_coding 17.92534 9.917721 17.88198 0.6881333 0.9319237 0.849779 2.6213071 0.000000 3.3004747 0.00000000 1.9881076 8.3708943 0.12193333 0.000000 0.188225 0.188225 0.59555395 0.04508066 FALSE  
ENST00000590949 ENSG00000126561 No_inf pgKDN_inf STAT5A protein_coding protein_coding 17.92534 9.917721 17.88198 0.6881333 0.9319237 0.849779 2.2434810 0.000000 4.0449809 0.00000000 2.4715458 8.6635513 0.10791667 0.000000 0.217500 0.217500 0.58628731 0.04508066 FALSE  
ENST00000676631 ENSG00000126561 No_inf pgKDN_inf STAT5A protein_coding protein_coding 17.92534 9.917721 17.88198 0.6881333 0.9319237 0.849779 0.8278695 0.488901 1.2741236 0.48890105 0.7636375 1.3639584 0.05381667 0.057575 0.074250 0.016675 0.84830076 0.04508066 FALSE  
ENST00000678903 ENSG00000126561 No_inf pgKDN_inf STAT5A protein_coding protein_coding 17.92534 9.917721 17.88198 0.6881333 0.9319237 0.849779 0.4824809 1.447443 0.0000000 0.83568797 0.0000000 -7.1872955 0.04383333 0.131500 0.000000 -0.131500 0.36051941 0.04508066 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000126561 E001 0.1187032 0.0118243832 1.0000000000   17 42287547 42287635 89 + 0.071 0.000 -10.594
ENSG00000126561 E002 0.0000000       17 42288056 42288075 20 +      
ENSG00000126561 E003 0.4746175 0.2389619272 0.2391560545   17 42288076 42288440 365 + 0.234 0.000 -14.093
ENSG00000126561 E004 0.1187032 0.0118243832 1.0000000000   17 42288441 42288468 28 + 0.071 0.000 -12.694
ENSG00000126561 E005 0.0000000       17 42288469 42288488 20 +      
ENSG00000126561 E006 0.0000000       17 42288489 42288495 7 +      
ENSG00000126561 E007 0.0000000       17 42288496 42288497 2 +      
ENSG00000126561 E008 0.0000000       17 42288498 42288500 3 +      
ENSG00000126561 E009 0.0000000       17 42288501 42288542 42 +      
ENSG00000126561 E010 0.0000000       17 42288543 42288598 56 +      
ENSG00000126561 E011 0.3621491 0.0166814950 1.0000000000   17 42289213 42289369 157 + 0.132 0.126 -0.084
ENSG00000126561 E012 0.0000000       17 42289370 42289401 32 +      
ENSG00000126561 E013 0.5906791 0.0144271977 0.0989661435 0.328449940 17 42289402 42289429 28 + 0.277 0.000 -14.724
ENSG00000126561 E014 2.1571880 0.0095709640 0.2601730938 0.552883490 17 42289430 42289539 110 + 0.543 0.370 -0.891
ENSG00000126561 E015 5.7724698 0.0042785827 0.1573087220 0.423854154 17 42289866 42290022 157 + 0.870 0.702 -0.669
ENSG00000126561 E016 0.1187032 0.0118243832 1.0000000000   17 42290023 42290179 157 + 0.071 0.000 -12.694
ENSG00000126561 E017 3.8572848 0.0093155953 0.4495048862 0.723178308 17 42291972 42292061 90 + 0.707 0.605 -0.438
ENSG00000126561 E018 9.3685195 0.0394352988 0.1903349773 0.469409971 17 42295619 42295793 175 + 1.054 0.888 -0.619
ENSG00000126561 E019 2.2769303 0.0063243449 0.2023567891 0.484804152 17 42299751 42299881 131 + 0.565 0.370 -0.991
ENSG00000126561 E020 0.0000000       17 42300130 42300281 152 +      
ENSG00000126561 E021 2.8789127 0.1023959905 0.4677319929 0.736040807 17 42300715 42300870 156 + 0.624 0.480 -0.667
ENSG00000126561 E022 11.4139734 0.0039148395 0.0561237832 0.236206018 17 42301275 42301454 180 + 1.135 0.958 -0.649
ENSG00000126561 E023 0.3804973 0.0158784945 0.0271807939   17 42304179 42304341 163 + 0.000 0.303 14.391
ENSG00000126561 E024 5.9216813 0.0023387674 0.7839237393 0.916834232 17 42304342 42304429 88 + 0.838 0.805 -0.128
ENSG00000126561 E025 6.9340657 0.0021119796 0.0033156096 0.037270548 17 42304530 42304646 117 + 0.980 0.640 -1.347
ENSG00000126561 E026 3.1249627 0.0047070275 0.2074182185 0.491017916 17 42304647 42304652 6 + 0.659 0.480 -0.821
ENSG00000126561 E027 6.5008073 0.0033208020 0.1760205789 0.450163303 17 42305610 42305702 93 + 0.910 0.756 -0.599
ENSG00000126561 E028 0.1271363 0.0123800325 0.2709630688   17 42306114 42306115 2 + 0.000 0.126 12.941
ENSG00000126561 E029 0.1271363 0.0123800325 0.2709630688   17 42306116 42306169 54 + 0.000 0.126 12.941
ENSG00000126561 E030 0.1271363 0.0123800325 0.2709630688   17 42306170 42306240 71 + 0.000 0.126 12.941
ENSG00000126561 E031 9.1085977 0.0434244822 0.6939554337 0.874902509 17 42306241 42306447 207 + 0.972 1.018 0.169
ENSG00000126561 E032 8.5048463 0.0017155106 0.4738245486 0.740734116 17 42307402 42307496 95 + 0.938 1.003 0.245
ENSG00000126561 E033 12.9358592 0.0012086949 0.6927624159 0.874346480 17 42307593 42307723 131 + 1.141 1.106 -0.125
ENSG00000126561 E034 16.2125201 0.0085165890 0.7231109613 0.888712665 17 42308178 42308333 156 + 1.231 1.198 -0.117
ENSG00000126561 E035 0.2374063 0.2379380274 0.6184433389   17 42308334 42308759 426 + 0.132 0.000 -13.193
ENSG00000126561 E036 7.6766048 0.0019019239 0.1685546413 0.439882220 17 42309047 42309098 52 + 0.870 1.003 0.501
ENSG00000126561 E037 8.2722576 0.0016946657 0.2506387354 0.541751757 17 42309377 42309484 108 + 0.910 1.018 0.401
ENSG00000126561 E038 5.0702555 0.0028178997 0.0001700182 0.003665115 17 42309485 42310506 1022 + 0.565 0.989 1.710
ENSG00000126561 E039 97.3314093 0.0002932292 0.0113032176 0.087192616 17 42310507 42311943 1437 + 1.954 2.012 0.196

Help

Please Click HERE to learn more details about the results from DEXseq.