ENSG00000126705

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000247087 ENSG00000126705 No_inf pgKDN_inf AHDC1 protein_coding protein_coding 9.220537 10.12289 9.203658 0.3852977 0.2973211 -0.1371999 1.1337982 2.2456423 0.7065342 1.0937234 0.7065342 -1.6544308 0.12287500 0.233175 0.081550 -0.151625 0.4154244 0.0231131 FALSE TRUE
ENST00000644833 ENSG00000126705 No_inf pgKDN_inf AHDC1 protein_coding protein_coding_CDS_not_defined 9.220537 10.12289 9.203658 0.3852977 0.2973211 -0.1371999 0.6958489 0.5874359 1.1186534 0.4401634 0.2691962 0.9177467 0.07399167 0.057400 0.119625 0.062225 0.5880410 0.0231131 FALSE TRUE
ENST00000644989 ENSG00000126705 No_inf pgKDN_inf AHDC1 protein_coding protein_coding 9.220537 10.12289 9.203658 0.3852977 0.2973211 -0.1371999 5.0288945 6.2520199 4.2439169 1.2050493 0.5862613 -0.5578363 0.53855833 0.607475 0.460125 -0.147350 0.7627460 0.0231131 FALSE TRUE
ENST00000673934 ENSG00000126705 No_inf pgKDN_inf AHDC1 protein_coding protein_coding 9.220537 10.12289 9.203658 0.3852977 0.2973211 -0.1371999 1.5993649 0.1295712 2.4557422 0.1295712 0.8387908 4.1429487 0.18412500 0.014350 0.268925 0.254575 0.0231131 0.0231131 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000126705 E001 0.5079806 0.0378018548 0.07929289 0.28875354 1 27534035 27534244 210 - 0.000 0.273 11.477
ENSG00000126705 E002 0.2454921 0.0163867060 0.85657888   1 27534245 27534272 28 - 0.105 0.086 -0.325
ENSG00000126705 E003 0.4801267 0.0153560362 0.21991119   1 27534273 27534302 30 - 0.260 0.086 -1.910
ENSG00000126705 E004 27.6538155 0.0004986022 0.09265233 0.31617277 1 27534303 27534660 358 - 1.395 1.491 0.330
ENSG00000126705 E005 8.3838527 0.0019565044 0.61344090 0.83193816 1 27534661 27534684 24 - 0.938 0.989 0.190
ENSG00000126705 E006 22.2726494 0.0006228335 0.75749714 0.90470716 1 27534685 27534916 232 - 1.350 1.372 0.076
ENSG00000126705 E007 188.7291799 0.0001287951 0.40980188 0.69191874 1 27547261 27550868 3608 - 2.265 2.280 0.050
ENSG00000126705 E008 23.8657504 0.0006718080 0.04199732 0.19942164 1 27550869 27551667 799 - 1.453 1.338 -0.399
ENSG00000126705 E009 5.9838688 0.0025472837 0.21576025 0.50165165 1 27551668 27551850 183 - 0.910 0.780 -0.502
ENSG00000126705 E010 4.9397222 0.0029018174 0.39231910 0.67732902 1 27551851 27552038 188 - 0.708 0.811 0.412
ENSG00000126705 E011 3.0487484 0.0048710850 0.24185686 0.53153387 1 27552039 27552189 151 - 0.684 0.532 -0.673
ENSG00000126705 E012 0.5070043 0.0156415173 0.07589442 0.28152425 1 27552496 27552772 277 - 0.000 0.273 13.330
ENSG00000126705 E013 0.0000000       1 27552773 27552891 119 -      
ENSG00000126705 E014 1.2085478 0.0114622923 0.10365070 0.33652160 1 27552892 27552929 38 - 0.465 0.219 -1.547
ENSG00000126705 E015 1.6992803 0.0708885619 0.17511300 0.44901325 1 27553074 27553140 67 - 0.540 0.321 -1.173
ENSG00000126705 E016 0.9728407 0.0160314522 0.30569271 0.59896585 1 27553141 27553145 5 - 0.375 0.219 -1.062
ENSG00000126705 E017 1.0901890 0.0134933009 0.18082114 0.45656705 1 27553146 27553185 40 - 0.422 0.219 -1.325
ENSG00000126705 E018 0.3807797 0.0236392319 0.15767902   1 27553186 27553225 40 - 0.000 0.219 12.946
ENSG00000126705 E019 0.9878868 0.0120357464 0.70396788 0.87961736 1 27553226 27553290 65 - 0.260 0.321 0.412
ENSG00000126705 E020 0.7437465 0.0140751066 0.59069551 0.81886807 1 27553291 27553298 8 - 0.190 0.273 0.675
ENSG00000126705 E021 0.6172395 0.0147851181 0.85041678 0.94698205 1 27553299 27553304 6 - 0.190 0.219 0.260
ENSG00000126705 E022 1.7056370 0.0370010243 0.36058136 0.65024726 1 27553305 27553545 241 - 0.504 0.364 -0.740
ENSG00000126705 E023 0.9718057 0.0118947839 0.30336406 0.59670897 1 27558305 27558328 24 - 0.375 0.219 -1.062
ENSG00000126705 E024 2.0416315 0.0368778954 0.01155064 0.08847782 1 27558329 27558530 202 - 0.659 0.273 -2.025
ENSG00000126705 E025 3.9534701 0.0755117287 0.60965179 0.83017463 1 27558706 27558813 108 - 0.632 0.730 0.412
ENSG00000126705 E026 3.0939751 0.0061286312 0.41159132 0.69313723 1 27558814 27558883 70 - 0.540 0.653 0.505
ENSG00000126705 E027 0.0000000       1 27568026 27568260 235 -      
ENSG00000126705 E028 1.8501476 0.0075698534 0.74522281 0.89920907 1 27603397 27603491 95 - 0.422 0.473 0.260
ENSG00000126705 E029 0.6064805 0.0168192228 0.48338913 0.74796776 1 27603492 27603494 3 - 0.260 0.158 -0.910
ENSG00000126705 E030 0.2441377 0.0163387019 0.85619867   1 27603495 27603633 139 - 0.105 0.086 -0.325
ENSG00000126705 E031 0.1187032 0.0118507133 0.42538866   1 27603728 27603863 136 - 0.105 0.000 -12.724
ENSG00000126705 E032 0.2543986 0.0161421323 0.33209353   1 27603864 27604101 238 - 0.000 0.158 12.433
ENSG00000126705 E033 0.1268540 0.0123366730 0.67652065   1 27604102 27604105 4 - 0.000 0.086 11.509
ENSG00000126705 E034 0.1268540 0.0123366730 0.67652065   1 27604106 27604109 4 - 0.000 0.086 11.509
ENSG00000126705 E035 0.1268540 0.0123366730 0.67652065   1 27604110 27604159 50 - 0.000 0.086 11.509
ENSG00000126705 E036 0.3612703 0.1687483029 0.49228196   1 27604160 27604431 272 - 0.190 0.086 -1.324

Help

Please Click HERE to learn more details about the results from DEXseq.