ENSG00000126775

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000247178 ENSG00000126775 No_inf pgKDN_inf ATG14 protein_coding protein_coding 7.306881 10.66633 5.83644 0.6630111 0.360339 -0.8687854 2.936399 2.127053 3.590593 0.5602374 0.2003007 0.7526118 0.4682417 0.19565 0.62580 0.43015 0.0269856 0.0269856 FALSE TRUE
ENST00000558189 ENSG00000126775 No_inf pgKDN_inf ATG14 protein_coding retained_intron 7.306881 10.66633 5.83644 0.6630111 0.360339 -0.8687854 1.818180 3.354626 1.022447 1.2292746 0.3182575 -1.7043783 0.2398250 0.33755 0.18445 -0.15310 0.8334612 0.0269856 FALSE TRUE
MSTRG.8565.3 ENSG00000126775 No_inf pgKDN_inf ATG14 protein_coding   7.306881 10.66633 5.83644 0.6630111 0.360339 -0.8687854 2.300854 4.594020 1.223400 1.0984656 0.8058265 -1.9002532 0.2666333 0.41925 0.18975 -0.22950 0.5072582 0.0269856 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000126775 E001 0.126507 0.0123708831 1.000000000   14 55366391 55366391 1 - 0.000 0.071 8.439
ENSG00000126775 E002 1.358470 0.0111297809 0.903037062 0.96886466 14 55366392 55366456 65 - 0.370 0.352 -0.105
ENSG00000126775 E003 94.078089 0.0002483396 0.311016946 0.60418989 14 55366457 55369925 3469 - 1.938 1.959 0.070
ENSG00000126775 E004 4.145057 0.0041282365 0.011815910 0.08970430 14 55377819 55377904 86 - 0.428 0.778 1.573
ENSG00000126775 E005 6.645655 0.0023735047 0.003884449 0.04159298 14 55377984 55378074 91 - 0.605 0.947 1.377
ENSG00000126775 E006 1.252513 0.0109505338 0.311695499 0.60492929 14 55378279 55378376 98 - 0.223 0.385 1.087
ENSG00000126775 E007 0.244893 0.0163960104 0.620041477   14 55380541 55380572 32 - 0.126 0.071 -0.913
ENSG00000126775 E008 4.792287 0.0043014405 0.137993565 0.39533331 14 55380573 55380690 118 - 0.848 0.676 -0.691
ENSG00000126775 E009 7.547868 0.0020021213 0.808822015 0.92942286 14 55381962 55382191 230 - 0.924 0.901 -0.087
ENSG00000126775 E010 7.229117 0.0099967915 0.050952509 0.22336606 14 55385859 55386096 238 - 1.017 0.815 -0.766
ENSG00000126775 E011 3.393031 0.0051067192 0.001470366 0.02013213 14 55390911 55390992 82 - 0.848 0.445 -1.761
ENSG00000126775 E012 3.000954 0.0054832907 0.140706844 0.39901587 14 55390993 55391302 310 - 0.428 0.642 1.013
ENSG00000126775 E013 0.508515 0.0160767535 0.167177572 0.43771393 14 55394649 55394674 26 - 0.000 0.234 11.949
ENSG00000126775 E014 2.683837 0.0059296914 0.057846453 0.24069515 14 55395940 55395982 43 - 0.702 0.445 -1.176
ENSG00000126775 E015 2.084316 0.0094152286 0.297776629 0.59081864 14 55397372 55397434 63 - 0.567 0.416 -0.743
ENSG00000126775 E016 2.216040 0.0542678298 0.435233903 0.71215052 14 55411602 55411830 229 - 0.567 0.445 -0.591

Help

Please Click HERE to learn more details about the results from DEXseq.