ENSG00000127314

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000341355 ENSG00000127314 No_inf pgKDN_inf RAP1B protein_coding protein_coding 139.9879 80.78338 184.5304 1.342554 8.025596 1.191628 78.630741 44.460532 103.456564 6.432106 5.6527982 1.218243 0.5621083 0.548450 0.566850 0.018400 0.97720733 0.04562328 FALSE  
ENST00000535492 ENSG00000127314 No_inf pgKDN_inf RAP1B protein_coding protein_coding 139.9879 80.78338 184.5304 1.342554 8.025596 1.191628 27.011003 12.306376 45.144278 1.277744 2.9655097 1.874285 0.1835500 0.152125 0.245150 0.093025 0.13058919 0.04562328 FALSE  
ENST00000540781 ENSG00000127314 No_inf pgKDN_inf RAP1B protein_coding protein_coding 139.9879 80.78338 184.5304 1.342554 8.025596 1.191628 9.777947 2.595122 12.597101 2.595122 8.6782721 2.274814 0.0620750 0.032525 0.063425 0.030900 0.87210291 0.04562328 FALSE  
ENST00000544639 ENSG00000127314 No_inf pgKDN_inf RAP1B protein_coding retained_intron 139.9879 80.78338 184.5304 1.342554 8.025596 1.191628 3.690211 6.115496 2.186008 1.117740 0.9441859 -1.479944 0.0351500 0.075925 0.011650 -0.064275 0.04562328 0.04562328 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000127314 E001 0.0000000       12 68610855 68610857 3 +      
ENSG00000127314 E002 0.2352613 0.2210238320 0.597817000   12 68610858 68610877 20 + 0.132 0.000 -10.311
ENSG00000127314 E003 0.8231686 0.0758592216 0.043963773 0.204894180 12 68610878 68610898 21 + 0.351 0.000 -14.091
ENSG00000127314 E004 1.1754339 0.1918045722 0.027673688 0.155134878 12 68610899 68610907 9 + 0.443 0.000 -14.482
ENSG00000127314 E005 1.1754339 0.1918045722 0.027673688 0.155134878 12 68610908 68610912 5 + 0.443 0.000 -14.482
ENSG00000127314 E006 1.1754339 0.1918045722 0.027673688 0.155134878 12 68610913 68610917 5 + 0.443 0.000 -14.482
ENSG00000127314 E007 1.1754339 0.1918045722 0.027673688 0.155134878 12 68610918 68610918 1 + 0.443 0.000 -14.482
ENSG00000127314 E008 5.8052597 0.0028666123 0.816922912 0.933368637 12 68610919 68610924 6 + 0.825 0.806 -0.076
ENSG00000127314 E009 7.2400660 0.0049830005 0.430431707 0.708318560 12 68610925 68610928 4 + 0.928 0.849 -0.298
ENSG00000127314 E010 9.6525684 0.0020329472 0.352931388 0.642835482 12 68610929 68610932 4 + 1.039 0.959 -0.298
ENSG00000127314 E011 10.8484644 0.0029771767 0.230965000 0.519382351 12 68610933 68610937 5 + 1.092 0.990 -0.375
ENSG00000127314 E012 10.8484644 0.0029771767 0.230965000 0.519382351 12 68610938 68610938 1 + 1.092 0.990 -0.375
ENSG00000127314 E013 17.8757989 0.0105519143 0.386253544 0.672114814 12 68610939 68610960 22 + 1.282 1.218 -0.225
ENSG00000127314 E014 38.6915092 0.0040815802 0.022700083 0.137189427 12 68610961 68611024 64 + 1.622 1.501 -0.414
ENSG00000127314 E015 26.8721267 0.0070170938 0.046759608 0.212337519 12 68611025 68611028 4 + 1.471 1.341 -0.453
ENSG00000127314 E016 29.9729508 0.0034916930 0.007755573 0.067663303 12 68611029 68611035 7 + 1.525 1.366 -0.547
ENSG00000127314 E017 33.5967032 0.0029706559 0.009813087 0.079289740 12 68611036 68611043 8 + 1.569 1.425 -0.493
ENSG00000127314 E018 8.2304839 0.0032175699 0.849442710 0.946457946 12 68611044 68611052 9 + 0.954 0.942 -0.044
ENSG00000127314 E019 0.2346346 0.0156063691 0.543278514   12 68611053 68611056 4 + 0.132 0.000 -12.382
ENSG00000127314 E020 0.1268540 0.0123238856 0.277330468   12 68621446 68621491 46 + 0.000 0.126 12.620
ENSG00000127314 E021 0.7339638 0.0143095869 0.454634219 0.727301476 12 68624508 68624670 163 + 0.186 0.304 0.924
ENSG00000127314 E022 0.9616083 0.0116995440 0.547690818 0.793125244 12 68624671 68624674 4 + 0.315 0.224 -0.661
ENSG00000127314 E023 1.2178593 0.0430139228 0.753630804 0.903108551 12 68624675 68624753 79 + 0.315 0.371 0.339
ENSG00000127314 E024 1.0864812 0.0112053243 0.919568946 0.974921015 12 68624754 68624873 120 + 0.315 0.304 -0.076
ENSG00000127314 E025 0.0000000       12 68641034 68641037 4 +      
ENSG00000127314 E026 0.1265070 0.0122657439 0.277360605   12 68641038 68641056 19 + 0.000 0.126 12.620
ENSG00000127314 E027 0.9881385 0.0163431266 0.118869510 0.364380163 12 68641057 68641153 97 + 0.186 0.429 1.661
ENSG00000127314 E028 1.7287777 0.2316232267 0.112615812 0.353047035 12 68647993 68648095 103 + 0.276 0.606 1.772
ENSG00000127314 E029 0.8433176 0.0324045030 0.722792583 0.888603311 12 68648670 68648698 29 + 0.276 0.224 -0.398
ENSG00000127314 E030 35.3811691 0.0029248791 0.003732199 0.040460786 12 68648699 68648705 7 + 1.595 1.436 -0.545
ENSG00000127314 E031 69.0933060 0.0002726217 0.087338500 0.306364657 12 68648706 68648781 76 + 1.848 1.793 -0.187
ENSG00000127314 E032 8.2377741 0.0316845613 0.005996963 0.056466511 12 68648782 68650041 1260 + 0.801 1.130 1.227
ENSG00000127314 E033 2.1212274 0.0065929895 0.000549468 0.009396007 12 68650244 68650399 156 + 0.233 0.731 2.625
ENSG00000127314 E034 66.6490442 0.0002354697 0.598395528 0.823930563 12 68650400 68650468 69 + 1.803 1.831 0.094
ENSG00000127314 E035 0.8709438 0.0131936590 0.051969986 0.226315962 12 68650469 68650882 414 + 0.132 0.429 2.246
ENSG00000127314 E036 0.5999674 0.2064921227 0.561162572 0.801593417 12 68651682 68651994 313 + 0.233 0.126 -1.077
ENSG00000127314 E037 40.9101485 0.0004302639 0.716191686 0.885525834 12 68651995 68652018 24 + 1.609 1.600 -0.031
ENSG00000127314 E038 49.7662728 0.0027444548 0.318178171 0.610965172 12 68652019 68652051 33 + 1.667 1.724 0.191
ENSG00000127314 E039 51.7535777 0.0051340276 0.751332865 0.902000818 12 68654112 68654124 13 + 1.696 1.721 0.084
ENSG00000127314 E040 69.7965785 0.0004008093 0.744465789 0.898798569 12 68654125 68654252 128 + 1.826 1.846 0.068
ENSG00000127314 E041 65.7117263 0.0002656109 0.044985763 0.207319672 12 68656306 68656449 144 + 1.776 1.858 0.279
ENSG00000127314 E042 0.3716522 0.1807818627 0.311961593   12 68656450 68656637 188 + 0.071 0.224 1.923
ENSG00000127314 E043 65.4570781 0.0003029986 0.059287903 0.244338600 12 68657101 68657217 117 + 1.776 1.854 0.265
ENSG00000127314 E044 0.2442663 0.0163507579 0.628235938   12 68657218 68657713 496 + 0.071 0.126 0.924
ENSG00000127314 E045 177.4724694 0.0105510963 0.023989689 0.141880729 12 68659280 68671901 12622 + 2.196 2.295 0.331

Help

Please Click HERE to learn more details about the results from DEXseq.