ENSG00000127334

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000344096 ENSG00000127334 No_inf pgKDN_inf DYRK2 protein_coding protein_coding 5.882351 5.009576 7.122231 0.3985143 0.2543539 0.5067879 3.7519188 2.172193 4.6437624 0.1914591 1.1715623 1.092619 0.63559167 0.445200 0.652775 0.207575 0.72153991 0.01202914 FALSE TRUE
ENST00000393555 ENSG00000127334 No_inf pgKDN_inf DYRK2 protein_coding protein_coding 5.882351 5.009576 7.122231 0.3985143 0.2543539 0.5067879 0.6841595 0.000000 1.8268367 0.0000000 1.2821550 7.521080 0.09856667 0.000000 0.254775 0.254775 0.59970148 0.01202914 FALSE TRUE
ENST00000537632 ENSG00000127334 No_inf pgKDN_inf DYRK2 protein_coding protein_coding_CDS_not_defined 5.882351 5.009576 7.122231 0.3985143 0.2543539 0.5067879 0.1195797 0.358739 0.0000000 0.3587390 0.0000000 -5.204528 0.01930833 0.057925 0.000000 -0.057925 0.82402080 0.01202914   FALSE
MSTRG.6776.6 ENSG00000127334 No_inf pgKDN_inf DYRK2 protein_coding   5.882351 5.009576 7.122231 0.3985143 0.2543539 0.5067879 0.9411548 2.478645 0.3448196 0.2506551 0.3448196 -2.810203 0.18325000 0.496900 0.052850 -0.444050 0.01202914 0.01202914 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000127334 E001 0.0000000       12 67648338 67648414 77 +      
ENSG00000127334 E002 0.4821733 0.0181052441 0.508628885   12 67648745 67648777 33 + 0.210 0.110 -1.100
ENSG00000127334 E003 7.1127841 0.0020074966 0.040730826 0.19582603 12 67648778 67649120 343 + 0.986 0.773 -0.820
ENSG00000127334 E004 4.1868248 0.0034719899 0.001963103 0.02520305 12 67649121 67649182 62 + 0.845 0.437 -1.788
ENSG00000127334 E005 0.0000000       12 67649682 67649796 115 +      
ENSG00000127334 E006 3.2892674 0.0355759324 0.949117666 0.98676200 12 67649797 67649945 149 + 0.635 0.622 -0.056
ENSG00000127334 E007 0.1170040 0.0118018564 0.752983439   12 67650768 67650794 27 + 0.082 0.000 -10.331
ENSG00000127334 E008 0.4816726 0.0192789821 0.508597123   12 67651469 67651658 190 + 0.210 0.110 -1.100
ENSG00000127334 E009 0.1272623 0.0123437034 0.381264045   12 67652501 67652700 200 + 0.000 0.110 10.019
ENSG00000127334 E010 232.9375197 0.0001183762 0.001031875 0.01534835 12 67657106 67665406 8301 + 2.358 2.374 0.054

Help

Please Click HERE to learn more details about the results from DEXseq.