ENSG00000127483

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000312239 ENSG00000127483 No_inf pgKDN_inf HP1BP3 protein_coding protein_coding 85.69455 94.64298 83.33736 3.508759 4.945656 -0.1835115 18.180832 21.646338 21.652464 6.8351960 2.1771309 0.0004080579 0.21085000 0.225875 0.264825 0.038950 0.84299131 0.01286567 FALSE TRUE
ENST00000375003 ENSG00000127483 No_inf pgKDN_inf HP1BP3 protein_coding protein_coding 85.69455 94.64298 83.33736 3.508759 4.945656 -0.1835115 6.303785 8.824598 4.862214 0.8258708 0.6847684 -0.8585869469 0.07295000 0.093525 0.058825 -0.034700 0.57795673 0.01286567 FALSE TRUE
ENST00000437575 ENSG00000127483 No_inf pgKDN_inf HP1BP3 protein_coding protein_coding 85.69455 94.64298 83.33736 3.508759 4.945656 -0.1835115 14.609696 14.737137 16.536111 3.2290308 5.1054212 0.1660572799 0.16667500 0.152700 0.190100 0.037400 0.86374174 0.01286567   FALSE
ENST00000487117 ENSG00000127483 No_inf pgKDN_inf HP1BP3 protein_coding protein_coding_CDS_not_defined 85.69455 94.64298 83.33736 3.508759 4.945656 -0.1835115 7.274323 8.914590 5.705251 0.6455899 0.2447339 -0.6429690106 0.08527500 0.094275 0.069650 -0.024625 0.76940032 0.01286567 FALSE TRUE
MSTRG.385.2 ENSG00000127483 No_inf pgKDN_inf HP1BP3 protein_coding   85.69455 94.64298 83.33736 3.508759 4.945656 -0.1835115 6.109584 5.468527 6.705017 3.7165013 2.4023713 0.2936030066 0.07085833 0.057975 0.078875 0.020900 0.81700125 0.01286567 FALSE TRUE
MSTRG.385.3 ENSG00000127483 No_inf pgKDN_inf HP1BP3 protein_coding   85.69455 94.64298 83.33736 3.508759 4.945656 -0.1835115 17.274190 12.930524 18.733631 4.4139345 3.7737764 0.5345044196 0.20889167 0.141850 0.225550 0.083700 0.81728859 0.01286567 FALSE TRUE
MSTRG.385.4 ENSG00000127483 No_inf pgKDN_inf HP1BP3 protein_coding   85.69455 94.64298 83.33736 3.508759 4.945656 -0.1835115 5.862276 13.498616 1.710595 2.0110563 1.7105951 -2.9729002761 0.06486667 0.141250 0.020750 -0.120500 0.01286567 0.01286567 FALSE TRUE
MSTRG.385.7 ENSG00000127483 No_inf pgKDN_inf HP1BP3 protein_coding   85.69455 94.64298 83.33736 3.508759 4.945656 -0.1835115 5.152465 5.900186 4.295776 0.7625898 0.3883930 -0.4569301224 0.06092500 0.063075 0.052650 -0.010425 0.89263637 0.01286567 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000127483 E001 2.6010035 0.0097648184 3.561983e-01 6.459934e-01 1 20740266 20742678 2413 - 0.470 0.603 0.626
ENSG00000127483 E002 0.9955343 0.0197376907 2.874032e-01 5.808156e-01 1 20742679 20742681 3 - 0.192 0.360 1.211
ENSG00000127483 E003 3.2216091 0.0274328923 3.989487e-01 6.827294e-01 1 20742682 20742719 38 - 0.545 0.668 0.543
ENSG00000127483 E004 124.1762116 0.0017304847 7.285466e-02 2.741657e-01 1 20742720 20743134 415 - 2.056 2.115 0.198
ENSG00000127483 E005 36.9584081 0.0004013617 4.675094e-01 7.358289e-01 1 20743135 20743174 40 - 1.551 1.589 0.131
ENSG00000127483 E006 574.5184184 0.0011709164 2.619669e-01 5.547105e-01 1 20743175 20744743 1569 - 2.743 2.762 0.063
ENSG00000127483 E007 138.8344211 0.0005932149 4.920881e-01 7.543924e-01 1 20744744 20745091 348 - 2.149 2.133 -0.053
ENSG00000127483 E008 40.9403234 0.0003999152 7.074410e-01 8.812835e-01 1 20745543 20745591 49 - 1.626 1.610 -0.052
ENSG00000127483 E009 52.9726617 0.0054029983 5.342362e-01 7.843982e-01 1 20745592 20745656 65 - 1.707 1.740 0.114
ENSG00000127483 E010 50.6590328 0.0003924796 4.018307e-01 6.849448e-01 1 20747544 20747614 71 - 1.685 1.723 0.129
ENSG00000127483 E011 38.3624728 0.0006003563 6.099349e-01 8.303202e-01 1 20747615 20747655 41 - 1.602 1.580 -0.077
ENSG00000127483 E012 70.0979846 0.0016933912 7.251452e-01 8.896518e-01 1 20749723 20749882 160 - 1.853 1.841 -0.039
ENSG00000127483 E013 3.8454937 0.0116842510 2.229079e-01 5.103283e-01 1 20749883 20749975 93 - 0.578 0.742 0.696
ENSG00000127483 E014 0.9991522 0.0121292229 2.839800e-01 5.777256e-01 1 20749976 20750251 276 - 0.192 0.360 1.211
ENSG00000127483 E015 28.6207697 0.0223317317 6.028782e-01 8.267224e-01 1 20757166 20757198 33 - 1.489 1.448 -0.139
ENSG00000127483 E016 34.1958351 0.0077033679 8.280541e-01 9.377386e-01 1 20757199 20757256 58 - 1.548 1.536 -0.041
ENSG00000127483 E017 60.2626635 0.0002519314 8.722324e-02 3.060702e-01 1 20765377 20765531 155 - 1.817 1.753 -0.215
ENSG00000127483 E018 46.1423893 0.0003162336 9.025936e-01 9.688647e-01 1 20767584 20767664 81 - 1.669 1.666 -0.011
ENSG00000127483 E019 62.6845997 0.0013885661 4.194391e-01 6.990306e-01 1 20770930 20771073 144 - 1.815 1.785 -0.102
ENSG00000127483 E020 0.2457744 0.0161796900 8.371030e-01   1 20771409 20771438 30 - 0.107 0.085 -0.374
ENSG00000127483 E021 60.4424129 0.0002508130 2.610531e-01 5.537495e-01 1 20773451 20773586 136 - 1.806 1.765 -0.139
ENSG00000127483 E022 29.2302761 0.0006204291 3.897972e-01 6.753396e-01 1 20773587 20773610 24 - 1.500 1.455 -0.156
ENSG00000127483 E023 122.9411485 0.0002273688 5.971127e-08 3.667959e-06 1 20773611 20775449 1839 - 1.991 2.145 0.516
ENSG00000127483 E024 16.5773804 0.0008197413 7.593044e-02 2.815416e-01 1 20775450 20775654 205 - 1.158 1.290 0.467
ENSG00000127483 E025 15.6815364 0.0204640564 3.350546e-01 6.268857e-01 1 20775655 20776005 351 - 1.158 1.255 0.344
ENSG00000127483 E026 33.9972839 0.0004069701 2.472311e-02 1.445441e-01 1 20776006 20776596 591 - 1.465 1.584 0.411
ENSG00000127483 E027 47.2687163 0.0002951082 7.000972e-03 6.305786e-02 1 20776597 20776697 101 - 1.741 1.626 -0.389
ENSG00000127483 E028 23.6857309 0.0005763486 1.858988e-03 2.416550e-02 1 20776698 20776712 15 - 1.485 1.299 -0.643
ENSG00000127483 E029 23.0790779 0.0009066264 2.606989e-03 3.104556e-02 1 20776713 20776719 7 - 1.473 1.290 -0.634
ENSG00000127483 E030 30.1732503 0.0058366581 3.332394e-03 3.736577e-02 1 20776720 20776750 31 - 1.584 1.403 -0.620
ENSG00000127483 E031 27.1399366 0.0005029960 5.821281e-03 5.522781e-02 1 20779812 20779835 24 - 1.526 1.372 -0.530
ENSG00000127483 E032 33.8253223 0.0004563660 5.212099e-02 2.267011e-01 1 20779836 20779911 76 - 1.590 1.493 -0.332
ENSG00000127483 E033 13.8207559 0.0013267391 4.938224e-01 7.556138e-01 1 20780345 20780349 5 - 1.132 1.188 0.200
ENSG00000127483 E034 45.5944529 0.0037673205 4.703110e-01 7.381211e-01 1 20780350 20780540 191 - 1.682 1.648 -0.117
ENSG00000127483 E035 0.2542726 0.2423009158 4.034909e-01   1 20780541 20780541 1 - 0.000 0.155 9.648
ENSG00000127483 E036 0.9786630 0.0116444190 7.113728e-01 8.833444e-01 1 20786186 20786252 67 - 0.325 0.270 -0.374
ENSG00000127483 E037 1.2329357 0.0106011949 8.291513e-01 9.382316e-01 1 20786253 20786513 261 - 0.325 0.360 0.211
ENSG00000127483 E038 3.7877188 0.0732998461 4.234392e-01 7.027222e-01 1 20786514 20786648 135 - 0.737 0.626 -0.468
ENSG00000127483 E039 2.4307265 0.0068734701 1.429993e-01 4.026417e-01 1 20786649 20786666 18 - 0.638 0.435 -0.959
ENSG00000127483 E040 14.3582915 0.0042796548 3.645461e-01 6.531820e-01 1 20787195 20787323 129 - 1.220 1.150 -0.251

Help

Please Click HERE to learn more details about the results from DEXseq.