ENSG00000127507

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000601345 ENSG00000127507 No_inf pgKDN_inf ADGRE2 protein_coding protein_coding 62.96796 23.03267 80.69016 0.5192513 2.835632 1.808263 2.322434 2.287766 2.436851 0.4111494 0.5572253 0.09069464 0.05165000 0.098275 0.030350 -0.067925 0.1597138468 0.0007445516 FALSE TRUE
MSTRG.14678.10 ENSG00000127507 No_inf pgKDN_inf ADGRE2 protein_coding   62.96796 23.03267 80.69016 0.5192513 2.835632 1.808263 26.060458 9.932385 33.997747 0.2380540 4.1499234 1.77419954 0.41769167 0.431525 0.419800 -0.011725 0.9786044024 0.0007445516   FALSE
MSTRG.14678.11 ENSG00000127507 No_inf pgKDN_inf ADGRE2 protein_coding   62.96796 23.03267 80.69016 0.5192513 2.835632 1.808263 8.674495 2.318575 12.333004 0.9193086 3.0826744 2.40617460 0.12955000 0.099900 0.154800 0.054900 0.8259438880 0.0007445516 FALSE TRUE
MSTRG.14678.13 ENSG00000127507 No_inf pgKDN_inf ADGRE2 protein_coding   62.96796 23.03267 80.69016 0.5192513 2.835632 1.808263 8.482346 3.248854 11.100114 1.1135438 0.9843925 1.76943695 0.13675833 0.143700 0.136975 -0.006725 0.9592592725 0.0007445516 TRUE TRUE
MSTRG.14678.14 ENSG00000127507 No_inf pgKDN_inf ADGRE2 protein_coding   62.96796 23.03267 80.69016 0.5192513 2.835632 1.808263 5.267963 0.000000 8.015581 0.0000000 2.7757444 9.64846210 0.06500833 0.000000 0.103250 0.103250 0.0007445516 0.0007445516 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000127507 E001 0.0000000       19 14732388 14732391 4 -      
ENSG00000127507 E002 0.0000000       19 14732392 14732395 4 -      
ENSG00000127507 E003 0.0000000       19 14732396 14732454 59 -      
ENSG00000127507 E004 0.0000000       19 14732455 14732507 53 -      
ENSG00000127507 E005 0.0000000       19 14732508 14732531 24 -      
ENSG00000127507 E006 0.0000000       19 14732532 14732545 14 -      
ENSG00000127507 E007 0.0000000       19 14732546 14732604 59 -      
ENSG00000127507 E008 0.0000000       19 14732605 14732609 5 -      
ENSG00000127507 E009 0.0000000       19 14732610 14732640 31 -      
ENSG00000127507 E010 0.0000000       19 14732641 14732704 64 -      
ENSG00000127507 E011 348.1977266 9.423252e-05 0.1135485934 0.354590824 19 14732705 14735575 2871 - 2.485 2.462 -0.075
ENSG00000127507 E012 117.0827957 1.616215e-04 0.6763457687 0.865844593 19 14735576 14736078 503 - 2.011 2.001 -0.037
ENSG00000127507 E013 29.0260311 8.175395e-04 0.5523002673 0.795880557 19 14736079 14736106 28 - 1.425 1.388 -0.126
ENSG00000127507 E014 43.6583186 4.159431e-03 0.3966279119 0.681286977 19 14736107 14736235 129 - 1.599 1.550 -0.166
ENSG00000127507 E015 13.2931682 2.410849e-02 0.3517506504 0.641942259 19 14736236 14736244 9 - 1.120 1.013 -0.391
ENSG00000127507 E016 1.1086387 1.743212e-01 0.0744054755 0.278100133 19 14737525 14737644 120 - 0.188 0.507 2.031
ENSG00000127507 E017 5.4163210 6.922668e-02 0.0001120753 0.002612113 19 14741475 14742086 612 - 0.536 1.097 2.240
ENSG00000127507 E018 31.3663575 1.517538e-02 0.7501415863 0.901457506 19 14743420 14743530 111 - 1.442 1.467 0.087
ENSG00000127507 E019 31.9789734 3.102217e-03 0.4582427928 0.730172146 19 14743616 14743763 148 - 1.444 1.493 0.167
ENSG00000127507 E020 10.7876561 1.299805e-03 0.5893178386 0.818001552 19 14743764 14743784 21 - 1.026 0.974 -0.193
ENSG00000127507 E021 22.7890062 7.669862e-03 0.8098666118 0.929822587 19 14746232 14746323 92 - 1.320 1.302 -0.064
ENSG00000127507 E022 19.0858388 7.550528e-04 0.9429119372 0.984120312 19 14746896 14746962 67 - 1.243 1.240 -0.013
ENSG00000127507 E023 18.4171006 2.358712e-03 0.4589451441 0.730704392 19 14751436 14751502 67 - 1.212 1.272 0.210
ENSG00000127507 E024 31.7761328 4.477574e-04 0.4356945662 0.712267843 19 14751503 14751671 169 - 1.465 1.419 -0.159
ENSG00000127507 E025 22.5691264 1.032638e-03 0.7062178687 0.880677103 19 14752329 14752421 93 - 1.317 1.292 -0.089
ENSG00000127507 E026 18.2745762 1.790899e-02 0.9689470169 0.993641226 19 14752422 14752526 105 - 1.223 1.229 0.020
ENSG00000127507 E027 23.6667781 5.867090e-04 0.9078058782 0.970698594 19 14754954 14755127 174 - 1.329 1.338 0.035
ENSG00000127507 E028 22.0601358 5.860333e-04 0.4529669334 0.725863966 19 14755654 14755844 191 - 1.315 1.261 -0.186
ENSG00000127507 E029 6.3653925 4.388370e-03 0.8628271808 0.952598864 19 14755845 14755877 33 - 0.807 0.829 0.087
ENSG00000127507 E030 12.8808069 2.803327e-02 0.0658974107 0.258556013 19 14756238 14756345 108 - 1.129 0.907 -0.815
ENSG00000127507 E031 18.7333069 4.165804e-03 0.9547747095 0.988991801 19 14764433 14764610 178 - 1.233 1.240 0.023
ENSG00000127507 E032 7.7376970 1.219785e-02 0.1131249497 0.353861125 19 14765320 14765397 78 - 0.834 1.013 0.675
ENSG00000127507 E033 1.6796121 7.956462e-03 0.8539645800 0.948420627 19 14765524 14765570 47 - 0.396 0.367 -0.166
ENSG00000127507 E034 0.5986766 4.430979e-02 0.9625294169 0.991861930 19 14765658 14765804 147 - 0.188 0.159 -0.291
ENSG00000127507 E035 2.1958424 6.543366e-03 0.0537893549 0.230760440 19 14765805 14766063 259 - 0.372 0.657 1.387
ENSG00000127507 E036 3.3203385 4.663472e-02 0.0015906502 0.021399383 19 14766064 14766234 171 - 0.419 0.883 2.031
ENSG00000127507 E037 2.4017331 8.462721e-03 0.8782315718 0.958623416 19 14766235 14766381 147 - 0.482 0.507 0.124
ENSG00000127507 E038 4.3205112 3.339648e-03 0.8551391745 0.948993338 19 14766978 14767085 108 - 0.680 0.657 -0.099
ENSG00000127507 E039 5.4092806 3.344884e-03 0.8849516481 0.961270084 19 14767086 14767109 24 - 0.748 0.768 0.081
ENSG00000127507 E040 1.2008432 6.955132e-01 0.8348711345 0.940551025 19 14768791 14768934 144 - 0.289 0.367 0.491
ENSG00000127507 E041 1.3524254 9.571559e-03 0.0286246391 0.158472652 19 14771880 14772341 462 - 0.225 0.563 1.972
ENSG00000127507 E042 21.2115026 6.534432e-04 0.1834750746 0.460379197 19 14772342 14772497 156 - 1.260 1.356 0.335
ENSG00000127507 E043 15.5724384 1.034244e-03 0.0815869609 0.293680182 19 14773938 14774054 117 - 1.120 1.261 0.502
ENSG00000127507 E044 6.5047439 3.498230e-03 0.4750196769 0.741675919 19 14774256 14774306 51 - 0.798 0.883 0.330
ENSG00000127507 E045 1.1030656 2.988180e-01 0.1146475942 0.356885798 19 14776404 14776725 322 - 0.188 0.507 2.033
ENSG00000127507 E046 7.0849695 1.703700e-02 0.9704327675 0.994112865 19 14776726 14776927 202 - 0.851 0.857 0.024
ENSG00000127507 E047 0.0000000       19 14777047 14777086 40 -      
ENSG00000127507 E048 0.1176306 1.180583e-02 1.0000000000   19 14778257 14778560 304 - 0.055 0.000 -6.978

Help

Please Click HERE to learn more details about the results from DEXseq.