ENSG00000127527

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000248070 ENSG00000127527 No_inf pgKDN_inf EPS15L1 protein_coding protein_coding 18.24938 18.13417 17.42726 1.962124 2.035407 -0.05733272 3.7380187 1.1563272 5.335010 1.1563272 1.0358831 2.19621990 0.1997500 0.060550 0.308050 0.247500 0.04908445 0.04908445 FALSE TRUE
ENST00000455140 ENSG00000127527 No_inf pgKDN_inf EPS15L1 protein_coding protein_coding 18.24938 18.13417 17.42726 1.962124 2.035407 -0.05733272 1.6540024 0.8733534 2.433247 0.8733534 0.9979982 1.46773730 0.0980750 0.041575 0.146925 0.105350 0.45410484 0.04908445 FALSE TRUE
ENST00000535753 ENSG00000127527 No_inf pgKDN_inf EPS15L1 protein_coding protein_coding 18.24938 18.13417 17.42726 1.962124 2.035407 -0.05733272 2.0052862 2.0212996 1.164006 1.1265730 1.1640056 -0.79096378 0.1087417 0.099150 0.071075 -0.028075 0.57926978 0.04908445 FALSE TRUE
ENST00000592031 ENSG00000127527 No_inf pgKDN_inf EPS15L1 protein_coding nonsense_mediated_decay 18.24938 18.13417 17.42726 1.962124 2.035407 -0.05733272 0.5751371 1.7254113 0.000000 1.1095565 0.0000000 -7.43913378 0.0345000 0.103500 0.000000 -0.103500 0.53360664 0.04908445 FALSE TRUE
ENST00000594851 ENSG00000127527 No_inf pgKDN_inf EPS15L1 protein_coding protein_coding 18.24938 18.13417 17.42726 1.962124 2.035407 -0.05733272 3.7454199 5.3615667 1.566215 1.8966581 1.5662152 -1.76887844 0.1809917 0.268200 0.066800 -0.201400 0.29833039 0.04908445   TRUE
ENST00000597937 ENSG00000127527 No_inf pgKDN_inf EPS15L1 protein_coding protein_coding 18.24938 18.13417 17.42726 1.962124 2.035407 -0.05733272 4.5412860 4.6369705 4.397830 0.1746847 0.5269874 -0.07622176 0.2555750 0.265600 0.258500 -0.007100 1.00000000 0.04908445 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000127527 E001 0.0000000       19 16355239 16355246 8 -      
ENSG00000127527 E002 18.1242759 0.0007790628 0.005429122 0.05254844 19 16355247 16355851 605 - 1.177 1.367 0.665
ENSG00000127527 E003 0.2537079 0.2724755791 0.271541435   19 16361579 16361580 2 - 0.000 0.180 11.543
ENSG00000127527 E004 0.3805619 0.5854811790 0.280188292   19 16361581 16361596 16 - 0.000 0.247 11.694
ENSG00000127527 E005 5.7330482 0.0030289623 0.662239666 0.85916801 19 16361597 16361778 182 - 0.850 0.804 -0.179
ENSG00000127527 E006 8.5329695 0.0022467945 0.399261051 0.68304718 19 16361779 16361885 107 - 1.015 0.938 -0.286
ENSG00000127527 E007 4.5192493 0.0031875502 0.812320493 0.93093565 19 16361886 16361888 3 - 0.754 0.728 -0.105
ENSG00000127527 E008 8.6815076 0.0026419157 0.811639635 0.93070279 19 16361889 16361984 96 - 0.995 0.975 -0.075
ENSG00000127527 E009 5.9447831 0.0028113487 0.117606106 0.36229420 19 16377122 16377254 133 - 0.917 0.749 -0.655
ENSG00000127527 E010 3.3032379 0.0045461040 0.976824741 0.99631358 19 16382989 16384275 1287 - 0.631 0.636 0.022
ENSG00000127527 E011 7.3260371 0.0292465075 0.702458823 0.87897199 19 16385129 16385211 83 - 0.941 0.898 -0.161
ENSG00000127527 E012 8.3078996 0.0070453841 0.714259843 0.88490053 19 16386171 16386231 61 - 0.985 0.951 -0.126
ENSG00000127527 E013 13.3567838 0.0050733771 0.749703921 0.90138846 19 16392304 16392440 137 - 1.142 1.171 0.102
ENSG00000127527 E014 9.0873710 0.0017723790 0.291073226 0.58463963 19 16393951 16394001 51 - 0.952 1.051 0.364
ENSG00000127527 E015 12.7648816 0.0026981874 0.157070361 0.42348694 19 16395344 16395467 124 - 1.191 1.079 -0.399
ENSG00000127527 E016 49.0354262 0.0004449969 0.002152716 0.02698851 19 16400631 16402314 1684 - 1.632 1.758 0.427
ENSG00000127527 E017 1.8304133 0.0323114116 0.937304348 0.98208705 19 16402315 16402320 6 - 0.458 0.446 -0.063
ENSG00000127527 E018 20.9696919 0.0006844680 0.320269365 0.61310990 19 16402321 16402485 165 - 1.371 1.311 -0.208
ENSG00000127527 E019 23.9750419 0.0005950127 0.070779981 0.26943058 19 16403733 16403930 198 - 1.446 1.342 -0.359
ENSG00000127527 E020 20.5426896 0.0006825768 0.028236330 0.15718106 19 16404588 16404749 162 - 1.396 1.259 -0.477
ENSG00000127527 E021 11.1150523 0.0018307181 0.739130979 0.89659238 19 16413773 16413845 73 - 1.096 1.070 -0.093
ENSG00000127527 E022 0.0000000       19 16417439 16417551 113 -      
ENSG00000127527 E023 9.4373796 0.0016783758 0.631313803 0.84185375 19 16417552 16417637 86 - 0.995 1.041 0.167
ENSG00000127527 E024 14.4077433 0.0026480583 0.644981628 0.84965168 19 16417948 16418104 157 - 1.204 1.171 -0.116
ENSG00000127527 E025 13.9528633 0.0010864628 0.788597687 0.91890468 19 16421319 16421476 158 - 1.164 1.186 0.078
ENSG00000127527 E026 4.6963608 0.0030740751 0.060378349 0.24653235 19 16425083 16425091 9 - 0.631 0.854 0.907
ENSG00000127527 E027 14.7457362 0.0183005819 0.174342336 0.44808089 19 16425092 16425316 225 - 1.135 1.253 0.419
ENSG00000127527 E028 7.3420491 0.0020215322 0.743822628 0.89868570 19 16428702 16428761 60 - 0.904 0.938 0.129
ENSG00000127527 E029 8.7497412 0.0044297335 0.203926719 0.48663504 19 16434365 16434483 119 - 1.044 0.925 -0.439
ENSG00000127527 E030 2.0285801 0.0643822285 0.019722642 0.12577994 19 16434484 16434490 7 - 0.631 0.247 -2.093
ENSG00000127527 E031 0.6173954 0.0230652031 0.589466472 0.81810993 19 16434491 16435296 806 - 0.167 0.247 0.714
ENSG00000127527 E032 0.0000000       19 16436596 16436936 341 -      
ENSG00000127527 E033 5.0963913 0.0028767920 0.203724520 0.48633109 19 16436937 16436999 63 - 0.850 0.707 -0.571
ENSG00000127527 E034 0.1272623 0.0122441028 0.494738596   19 16437000 16437064 65 - 0.000 0.099 11.238
ENSG00000127527 E035 7.2287471 0.0248890421 0.650189515 0.85265422 19 16437770 16437865 96 - 0.891 0.938 0.178
ENSG00000127527 E036 0.3729107 0.2284118694 0.579423071   19 16440653 16440861 209 - 0.091 0.180 1.129
ENSG00000127527 E037 4.0443403 0.0193468204 0.680616622 0.86816715 19 16440862 16440884 23 - 0.676 0.728 0.216
ENSG00000127527 E038 5.5053708 0.0536148174 0.893923147 0.96493247 19 16440885 16440909 25 - 0.805 0.822 0.065
ENSG00000127527 E039 0.1272623 0.0122441028 0.494738596   19 16441511 16441891 381 - 0.000 0.099 11.238
ENSG00000127527 E040 5.8371186 0.0351289595 0.342271990 0.63369326 19 16441892 16441981 90 - 0.891 0.768 -0.481
ENSG00000127527 E041 2.4500236 0.1651753831 0.939828101 0.98292945 19 16442178 16442219 42 - 0.524 0.551 0.129
ENSG00000127527 E042 1.8237520 0.1536234623 0.646103037 0.85024316 19 16471913 16472085 173 - 0.492 0.404 -0.456

Help

Please Click HERE to learn more details about the results from DEXseq.