ENSG00000127586

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000317063 ENSG00000127586 No_inf pgKDN_inf CHTF18 protein_coding protein_coding 19.45661 24.93646 10.5823 2.199286 2.142693 -1.235819 1.194898 0.6386498 1.5330984 0.6386498 1.0275934 1.2503183 0.10360833 0.026725 0.188875 0.162150 6.994694e-01 1.463291e-05 FALSE TRUE
ENST00000464728 ENSG00000127586 No_inf pgKDN_inf CHTF18 protein_coding retained_intron 19.45661 24.93646 10.5823 2.199286 2.142693 -1.235819 1.198966 2.3324100 0.0000000 1.1003155 0.0000000 -7.8718498 0.05541667 0.097375 0.000000 -0.097375 2.014322e-01 1.463291e-05 FALSE TRUE
ENST00000493715 ENSG00000127586 No_inf pgKDN_inf CHTF18 protein_coding protein_coding_CDS_not_defined 19.45661 24.93646 10.5823 2.199286 2.142693 -1.235819 3.116581 5.0512597 0.0000000 0.7184193 0.0000000 -8.9833527 0.12680000 0.204050 0.000000 -0.204050 1.463291e-05 1.463291e-05 FALSE FALSE
ENST00000565787 ENSG00000127586 No_inf pgKDN_inf CHTF18 protein_coding retained_intron 19.45661 24.93646 10.5823 2.199286 2.142693 -1.235819 1.070237 2.9083813 0.0000000 1.6862246 0.0000000 -8.1890246 0.04150833 0.113725 0.000000 -0.113725 6.701245e-01 1.463291e-05 FALSE FALSE
ENST00000570058 ENSG00000127586 No_inf pgKDN_inf CHTF18 protein_coding protein_coding_CDS_not_defined 19.45661 24.93646 10.5823 2.199286 2.142693 -1.235819 2.883541 3.9664248 1.4376303 3.0807192 1.4376303 -1.4577787 0.11220000 0.148075 0.085125 -0.062950 8.763618e-01 1.463291e-05 FALSE TRUE
MSTRG.10388.2 ENSG00000127586 No_inf pgKDN_inf CHTF18 protein_coding   19.45661 24.93646 10.5823 2.199286 2.142693 -1.235819 1.571456 1.7314819 2.0755618 0.8067344 0.3695212 0.2601206 0.10210000 0.066275 0.211125 0.144850 3.944110e-01 1.463291e-05 FALSE TRUE
MSTRG.10388.22 ENSG00000127586 No_inf pgKDN_inf CHTF18 protein_coding   19.45661 24.93646 10.5823 2.199286 2.142693 -1.235819 1.597799 2.0531332 1.5899727 1.2602240 0.6129332 -0.3667897 0.09020833 0.075925 0.155500 0.079575 7.876289e-01 1.463291e-05 FALSE TRUE
MSTRG.10388.5 ENSG00000127586 No_inf pgKDN_inf CHTF18 protein_coding   19.45661 24.93646 10.5823 2.199286 2.142693 -1.235819 1.667891 2.6637639 0.6009541 0.7178356 0.4586027 -2.1297361 0.09350000 0.115775 0.075600 -0.040175 7.369973e-01 1.463291e-05 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000127586 E001 0.4830507 0.4541142084 0.26090181   16 788046 788116 71 + 0.308 0.070 -2.564
ENSG00000127586 E002 0.1186381 0.0118402459 0.25629780   16 788165 788577 413 + 0.128 0.000 -13.548
ENSG00000127586 E003 0.0000000       16 788578 788619 42 +      
ENSG00000127586 E004 0.0000000       16 788620 788621 2 +      
ENSG00000127586 E005 0.0000000       16 788622 788623 2 +      
ENSG00000127586 E006 0.0000000       16 788624 788624 1 +      
ENSG00000127586 E007 0.0000000       16 788625 788634 10 +      
ENSG00000127586 E008 0.3814089 0.6085150925 0.62698526   16 788635 788645 11 + 0.000 0.183 12.567
ENSG00000127586 E009 0.5086713 0.2357211185 0.25452111 0.5462678 16 788646 788649 4 + 0.000 0.230 13.087
ENSG00000127586 E010 0.6355253 0.0615123184 0.11787287 0.3626412 16 788650 788655 6 + 0.000 0.272 13.464
ENSG00000127586 E011 7.8321426 0.0063716311 0.41627573 0.6961548 16 788656 788756 101 + 0.856 0.947 0.345
ENSG00000127586 E012 6.0654771 0.0023460450 0.85479659 0.9487889 16 788757 788775 19 + 0.835 0.818 -0.065
ENSG00000127586 E013 0.0000000       16 788928 788930 3 +      
ENSG00000127586 E014 10.3620001 0.0026861349 0.27063201 0.5643181 16 788931 789085 155 + 1.091 0.995 -0.349
ENSG00000127586 E015 4.2026719 0.0037749913 0.56161727 0.8018608 16 789086 789125 40 + 0.738 0.669 -0.285
ENSG00000127586 E016 0.7326703 0.0330860383 0.41433168 0.6946193 16 789126 789209 84 + 0.308 0.183 -0.977
ENSG00000127586 E017 3.8129856 0.0235286822 0.20259471 0.4850927 16 789210 789213 4 + 0.764 0.598 -0.697
ENSG00000127586 E018 3.6857883 0.0114697133 0.14614323 0.4070823 16 789214 789216 3 + 0.764 0.579 -0.785
ENSG00000127586 E019 7.9279968 0.0019940711 0.87768764 0.9584953 16 789217 789312 96 + 0.932 0.920 -0.044
ENSG00000127586 E020 3.8801204 0.0206084707 0.09725959 0.3248250 16 789313 789318 6 + 0.486 0.729 1.082
ENSG00000127586 E021 4.9634870 0.0543982023 0.64441992 0.8494535 16 789319 789360 42 + 0.709 0.770 0.246
ENSG00000127586 E022 0.0000000       16 789361 789362 2 +      
ENSG00000127586 E023 0.2346346 0.0156774780 0.08235769   16 789363 789546 184 + 0.227 0.000 -14.499
ENSG00000127586 E024 2.9585051 0.1227728056 0.88651302 0.9620361 16 789547 789548 2 + 0.611 0.558 -0.239
ENSG00000127586 E025 5.2151181 0.1030185725 0.46612237 0.7349130 16 789549 789615 67 + 0.709 0.795 0.346
ENSG00000127586 E026 6.5733615 0.0021972072 0.83006873 0.9384086 16 789616 789715 100 + 0.835 0.862 0.105
ENSG00000127586 E027 0.2442663 0.0162776683 0.59168132   16 790007 790057 51 + 0.128 0.070 -0.977
ENSG00000127586 E028 0.0000000       16 790058 790081 24 +      
ENSG00000127586 E029 0.0000000       16 790082 790176 95 +      
ENSG00000127586 E030 6.1943399 0.0024689987 0.93441236 0.9810672 16 790177 790250 74 + 0.835 0.830 -0.020
ENSG00000127586 E031 3.6917302 0.0265598222 0.30046291 0.5933051 16 790251 790269 19 + 0.738 0.598 -0.590
ENSG00000127586 E032 0.1265070 0.0122415714 1.00000000   16 790331 790346 16 + 0.000 0.070 11.302
ENSG00000127586 E033 4.5616364 0.0641218002 0.46560592 0.7345731 16 790347 790399 53 + 0.789 0.685 -0.425
ENSG00000127586 E034 1.9504932 0.1532603356 0.14657745 0.4076740 16 790525 790525 1 + 0.612 0.347 -1.341
ENSG00000127586 E035 2.2048919 0.0784781846 0.21452159 0.4999355 16 790526 790530 5 + 0.612 0.410 -0.978
ENSG00000127586 E036 7.5316892 0.0045352314 0.34226280 0.6336933 16 790531 790666 136 + 0.966 0.872 -0.353
ENSG00000127586 E037 1.4972529 0.0092100567 0.52855481 0.7802047 16 790667 790671 5 + 0.308 0.410 0.608
ENSG00000127586 E038 1.6245153 0.0092473731 0.41801413 0.6976906 16 790672 790698 27 + 0.308 0.438 0.760
ENSG00000127586 E039 11.0326383 0.0030217610 0.87006722 0.9552408 16 790699 791136 438 + 1.040 1.059 0.072
ENSG00000127586 E040 1.7337129 0.0078183149 0.85975177 0.9513131 16 791137 791160 24 + 0.434 0.410 -0.129
ENSG00000127586 E041 13.3135777 0.0010064157 0.22415705 0.5117376 16 791161 791370 210 + 1.053 1.159 0.383
ENSG00000127586 E042 15.2573271 0.0173085617 0.74786771 0.9005752 16 791371 791850 480 + 1.158 1.195 0.130
ENSG00000127586 E043 4.6818533 0.0030670721 0.26970558 0.5633438 16 791851 791905 55 + 0.813 0.685 -0.518
ENSG00000127586 E044 5.3331511 0.0026404624 0.90191288 0.9685749 16 791906 791948 43 + 0.764 0.782 0.073
ENSG00000127586 E045 10.0135354 0.0093271808 0.01220851 0.0915313 16 791949 792223 275 + 0.813 1.085 1.023
ENSG00000127586 E046 11.5421214 0.0345802207 0.74654911 0.8997024 16 792224 792347 124 + 1.040 1.085 0.164
ENSG00000127586 E047 0.8876277 0.0123373485 0.04126453 0.1972141 16 792348 792367 20 + 0.000 0.347 13.934
ENSG00000127586 E048 1.2371842 0.0992735172 0.70315646 0.8792148 16 792368 792438 71 + 0.376 0.311 -0.393
ENSG00000127586 E049 9.3908743 0.0020069079 0.39098600 0.6762479 16 792439 792523 85 + 1.040 0.964 -0.281
ENSG00000127586 E050 7.4298411 0.0231564315 0.97786820 0.9967747 16 792524 792590 67 + 0.896 0.902 0.023
ENSG00000127586 E051 9.5302544 0.0184530470 0.78981225 0.9194020 16 792718 792811 94 + 1.012 0.988 -0.088
ENSG00000127586 E052 0.0000000       16 792812 792814 3 +      
ENSG00000127586 E053 4.8376561 0.0039222965 0.98724042 0.9996378 16 792966 792980 15 + 0.738 0.743 0.023
ENSG00000127586 E054 8.7219545 0.0023976199 0.25761876 0.5499056 16 792981 793064 84 + 0.877 0.995 0.447
ENSG00000127586 E055 12.0649921 0.0113323432 0.37829051 0.6652936 16 793144 793274 131 + 1.026 1.115 0.324
ENSG00000127586 E056 0.0000000       16 793658 793802 145 +      
ENSG00000127586 E057 0.2459655 0.0164996854 0.59109749   16 794040 794053 14 + 0.128 0.070 -0.977
ENSG00000127586 E058 9.0517304 0.0014767308 0.91649234 0.9737086 16 794054 794141 88 + 0.966 0.980 0.053
ENSG00000127586 E059 6.8046295 0.0038342006 0.86960990 0.9551341 16 794142 794201 60 + 0.876 0.862 -0.055
ENSG00000127586 E060 1.0162746 0.0114134450 0.02570466 0.1480674 16 794702 794844 143 + 0.000 0.379 14.109
ENSG00000127586 E061 21.2171384 0.0007914089 0.71505715 0.8851661 16 795132 795356 225 + 1.299 1.327 0.099
ENSG00000127586 E062 15.9998840 0.0009829384 0.82728852 0.9374822 16 795685 795834 150 + 1.188 1.209 0.073
ENSG00000127586 E063 11.5900939 0.0012423560 0.10866693 0.3459561 16 795947 796077 131 + 0.966 1.115 0.546
ENSG00000127586 E064 0.7518676 0.2496413501 0.52122284 0.7753053 16 796615 796716 102 + 0.128 0.272 1.343
ENSG00000127586 E065 15.8402097 0.0164319704 0.69455011 0.8752285 16 796717 796861 145 + 1.216 1.190 -0.094
ENSG00000127586 E066 14.6649864 0.0009051489 0.07576574 0.2812547 16 796961 797092 132 + 1.251 1.121 -0.463
ENSG00000127586 E067 8.6414346 0.0015718880 0.36965935 0.6578634 16 797694 797751 58 + 1.012 0.929 -0.306
ENSG00000127586 E068 11.4915398 0.0083343658 0.42764311 0.7062220 16 797839 798040 202 + 1.115 1.046 -0.248
ENSG00000127586 E069 0.0000000       16 798041 798186 146 +      
ENSG00000127586 E070 0.0000000       16 800687 800737 51 +      

Help

Please Click HERE to learn more details about the results from DEXseq.