ENSG00000127616

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000538456 ENSG00000127616 No_inf pgKDN_inf SMARCA4 protein_coding protein_coding 49.97977 41.37345 51.94822 0.7944864 1.400194 0.3282978 5.202588 3.504719 4.381314 2.4828125 2.5320319 0.3212431 0.10025000 0.081875 0.081975 0.000100 1.000000000 0.003553619 FALSE TRUE
ENST00000642508 ENSG00000127616 No_inf pgKDN_inf SMARCA4 protein_coding protein_coding 49.97977 41.37345 51.94822 0.7944864 1.400194 0.3282978 2.655990 1.968725 2.580787 1.1444179 1.6893070 0.3888191 0.05246667 0.048725 0.049850 0.001125 1.000000000 0.003553619 FALSE TRUE
ENST00000644065 ENSG00000127616 No_inf pgKDN_inf SMARCA4 protein_coding protein_coding 49.97977 41.37345 51.94822 0.7944864 1.400194 0.3282978 6.563870 1.908295 7.566248 1.3583039 2.6980587 1.9816590 0.12416667 0.046350 0.145250 0.098900 0.620465948 0.003553619 FALSE TRUE
ENST00000645460 ENSG00000127616 No_inf pgKDN_inf SMARCA4 protein_coding protein_coding 49.97977 41.37345 51.94822 0.7944864 1.400194 0.3282978 1.324765 2.180116 0.000000 1.3034824 0.0000000 -7.7748635 0.02760833 0.052800 0.000000 -0.052800 0.454379061 0.003553619 FALSE TRUE
ENST00000646889 ENSG00000127616 No_inf pgKDN_inf SMARCA4 protein_coding retained_intron 49.97977 41.37345 51.94822 0.7944864 1.400194 0.3282978 3.518256 7.425841 1.201497 0.5049569 0.4858467 -2.6177054 0.07927500 0.180050 0.023225 -0.156825 0.003553619 0.003553619 FALSE TRUE
ENST00000647230 ENSG00000127616 No_inf pgKDN_inf SMARCA4 protein_coding protein_coding 49.97977 41.37345 51.94822 0.7944864 1.400194 0.3282978 8.255384 3.319201 10.720959 1.1717068 4.4093816 1.6885311 0.16153333 0.081850 0.209175 0.127325 0.835767094 0.003553619 FALSE TRUE
ENST00000647268 ENSG00000127616 No_inf pgKDN_inf SMARCA4 protein_coding protein_coding 49.97977 41.37345 51.94822 0.7944864 1.400194 0.3282978 7.087408 7.254662 9.491140 0.5615434 1.8983099 0.3872049 0.14572500 0.176200 0.182575 0.006375 1.000000000 0.003553619 FALSE TRUE
MSTRG.14530.12 ENSG00000127616 No_inf pgKDN_inf SMARCA4 protein_coding   49.97977 41.37345 51.94822 0.7944864 1.400194 0.3282978 3.034211 2.619083 5.744403 2.6190834 3.5058736 1.1301064 0.06080000 0.060325 0.108650 0.048325 0.846159017 0.003553619 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000127616 E001 0.0000000       19 10960932 10960956 25 +      
ENSG00000127616 E002 0.0000000       19 10960957 10960991 35 +      
ENSG00000127616 E003 0.0000000       19 10960992 10961000 9 +      
ENSG00000127616 E004 0.0000000       19 10961001 10961009 9 +      
ENSG00000127616 E005 0.4709684 0.0159981193 9.067795e-02   19 10961010 10961018 9 + 0.263 0.000 -11.696
ENSG00000127616 E006 0.9507482 0.0119824493 7.122827e-02 2.704418e-01 19 10961019 10961029 11 + 0.391 0.110 -2.345
ENSG00000127616 E007 1.5514945 0.0085756268 3.967068e-02 1.930578e-01 19 10961030 10961042 13 + 0.518 0.197 -1.997
ENSG00000127616 E008 1.9159721 0.0071598154 4.907637e-02 2.184259e-01 19 10961043 10961056 14 + 0.569 0.270 -1.653
ENSG00000127616 E009 3.0137466 0.0047766745 1.481264e-01 4.098209e-01 19 10961057 10961080 24 + 0.677 0.479 -0.900
ENSG00000127616 E010 4.3453119 0.0032649270 1.572822e-01 4.238542e-01 19 10961081 10961104 24 + 0.793 0.619 -0.722
ENSG00000127616 E011 3.5132018 0.0039727146 4.052710e-01 6.880353e-01 19 10961105 10961109 5 + 0.696 0.588 -0.464
ENSG00000127616 E012 6.1951535 0.0022551602 6.762300e-01 8.658391e-01 19 10961110 10961174 65 + 0.873 0.829 -0.170
ENSG00000127616 E013 0.0000000       19 10961321 10961572 252 +      
ENSG00000127616 E014 0.2374063 0.2443577864 4.296235e-01   19 10961573 10961729 157 + 0.151 0.000 -13.021
ENSG00000127616 E015 0.1268540 0.0123318964 3.889714e-01   19 10965307 10965309 3 + 0.000 0.110 12.578
ENSG00000127616 E016 0.0000000       19 10977653 10977815 163 +      
ENSG00000127616 E017 0.2459004 0.0164381179 8.051803e-01   19 10980777 10980852 76 + 0.082 0.110 0.462
ENSG00000127616 E018 0.0000000       19 10983480 10983711 232 +      
ENSG00000127616 E019 2.7905462 0.0050266337 7.729457e-01 9.125992e-01 19 10984121 10984123 3 + 0.593 0.555 -0.175
ENSG00000127616 E020 10.8618020 0.0012576736 1.867588e-02 1.212942e-01 19 10984124 10984278 155 + 1.150 0.942 -0.760
ENSG00000127616 E021 10.4984283 0.0013984059 1.970463e-02 1.257394e-01 19 10984279 10984373 95 + 1.137 0.928 -0.768
ENSG00000127616 E022 11.0591959 0.0012923823 6.224597e-01 8.373273e-01 19 10985273 10985405 133 + 1.096 1.055 -0.149
ENSG00000127616 E023 19.3961540 0.0007322120 9.535751e-02 3.214985e-01 19 10986189 10986419 231 + 1.352 1.240 -0.391
ENSG00000127616 E024 17.1973281 0.0009715849 6.587670e-02 2.585123e-01 19 10986420 10986593 174 + 1.309 1.178 -0.462
ENSG00000127616 E025 10.8127039 0.0015943779 4.572228e-01 7.292363e-01 19 10986905 10987003 99 + 1.096 1.032 -0.232
ENSG00000127616 E026 22.8306947 0.0011512158 2.936577e-01 5.871847e-01 19 10987666 10987924 259 + 1.401 1.336 -0.226
ENSG00000127616 E027 17.0915278 0.0300066471 5.030939e-01 7.626537e-01 19 10989317 10989424 108 + 1.227 1.288 0.215
ENSG00000127616 E028 9.3991431 0.0042237891 5.680501e-01 8.056883e-01 19 10989425 10989443 19 + 0.989 1.044 0.199
ENSG00000127616 E029 10.2326023 0.0013270141 8.931220e-01 9.645186e-01 19 10991150 10991174 25 + 1.042 1.055 0.047
ENSG00000127616 E030 20.1802740 0.0006770520 6.464063e-01 8.503860e-01 19 10991175 10991259 85 + 1.335 1.306 -0.101
ENSG00000127616 E031 17.8331868 0.0008570790 2.485093e-01 5.393385e-01 19 10991260 10991323 64 + 1.305 1.225 -0.280
ENSG00000127616 E032 14.4071235 0.0009797178 5.921006e-02 2.442406e-01 19 10994828 10994851 24 + 1.242 1.097 -0.520
ENSG00000127616 E033 22.4439171 0.0006196807 1.387186e-01 3.960658e-01 19 10994852 10994920 69 + 1.405 1.313 -0.321
ENSG00000127616 E034 21.1682950 0.0006511530 8.425337e-01 9.436056e-01 19 10994921 10994997 77 + 1.348 1.336 -0.040
ENSG00000127616 E035 10.2209612 0.0013039584 9.322951e-01 9.802842e-01 19 10994998 10995001 4 + 1.050 1.044 -0.023
ENSG00000127616 E036 15.5642205 0.0009333161 7.321306e-01 8.935671e-01 19 10996213 10996263 51 + 1.227 1.202 -0.085
ENSG00000127616 E037 8.7322192 0.0093417171 4.591875e-01 7.309432e-01 19 10996264 10996264 1 + 1.016 0.942 -0.275
ENSG00000127616 E038 9.3231192 0.0055711390 2.261734e-01 5.142029e-01 19 10996265 10996273 9 + 1.058 0.942 -0.427
ENSG00000127616 E039 12.5389161 0.0012305576 9.384955e-01 9.822325e-01 19 10996274 10996316 43 + 1.131 1.126 -0.018
ENSG00000127616 E040 10.0883175 0.0013547736 6.646629e-01 8.605914e-01 19 10996317 10996334 18 + 1.058 1.020 -0.137
ENSG00000127616 E041 15.8084115 0.0008503873 7.553845e-01 9.035894e-01 19 10996335 10996380 46 + 1.232 1.210 -0.077
ENSG00000127616 E042 11.0364892 0.0012512552 3.590874e-01 6.485300e-01 19 10996494 10996496 3 + 1.110 1.032 -0.283
ENSG00000127616 E043 18.4285030 0.0007337621 1.870198e-01 4.648610e-01 19 10996497 10996544 48 + 1.323 1.233 -0.315
ENSG00000127616 E044 16.1391316 0.0008696595 2.909416e-01 5.844627e-01 19 11003029 11003109 81 + 1.263 1.187 -0.269
ENSG00000127616 E045 10.5673385 0.0012823612 4.301143e-01 7.081347e-01 19 11003110 11003152 43 + 1.089 1.020 -0.248
ENSG00000127616 E046 9.3575404 0.0015729511 5.765922e-01 8.105275e-01 19 11003153 11003159 7 + 1.033 0.983 -0.185
ENSG00000127616 E047 17.1056661 0.0008972394 2.080333e-01 4.917977e-01 19 11003340 11003397 58 + 1.291 1.202 -0.313
ENSG00000127616 E048 11.0204306 0.0012336637 1.785717e-01 4.534409e-01 19 11007902 11007910 9 + 1.124 1.008 -0.420
ENSG00000127616 E049 26.0434320 0.0044966965 7.819827e-01 9.161408e-01 19 11007911 11008023 113 + 1.436 1.420 -0.056
ENSG00000127616 E050 0.2451451 0.0164789279 8.053213e-01   19 11008024 11008323 300 + 0.082 0.110 0.462
ENSG00000127616 E051 13.3096845 0.0238050894 6.495016e-01 8.523168e-01 19 11010381 11010393 13 + 1.131 1.178 0.170
ENSG00000127616 E052 29.2772892 0.0004722448 4.437179e-01 7.184357e-01 19 11010394 11010531 138 + 1.458 1.502 0.148
ENSG00000127616 E053 1.2709556 0.0244029360 1.053477e-04 2.477194e-03 19 11012344 11012948 605 + 0.000 0.588 15.580
ENSG00000127616 E054 35.1236005 0.0004721797 3.565540e-01 6.463559e-01 19 11012949 11013112 164 + 1.574 1.528 -0.156
ENSG00000127616 E055 0.0000000       19 11018312 11018331 20 +      
ENSG00000127616 E056 0.0000000       19 11018870 11018956 87 +      
ENSG00000127616 E057 16.3088623 0.0010485743 9.133335e-03 7.576959e-02 19 11018957 11019013 57 + 1.309 1.116 -0.685
ENSG00000127616 E058 10.2547679 0.0073658385 2.348807e-02 1.400559e-01 19 11019014 11019023 10 + 1.131 0.913 -0.801
ENSG00000127616 E059 0.1186381 0.0118352636 7.392986e-01   19 11019024 11019590 567 + 0.082 0.000 -12.879
ENSG00000127616 E060 10.6178229 0.0014551972 1.590812e-02 1.093815e-01 19 11019591 11019602 12 + 1.144 0.928 -0.792
ENSG00000127616 E061 25.9564750 0.0039829220 1.945911e-01 4.745683e-01 19 11019603 11019701 99 + 1.462 1.380 -0.282
ENSG00000127616 E062 0.6075454 0.0185129401 9.234906e-01 9.766915e-01 19 11020581 11021724 1144 + 0.211 0.197 -0.123
ENSG00000127616 E063 13.6530211 0.0012199864 7.314456e-01 8.932539e-01 19 11021725 11021747 23 + 1.150 1.178 0.100
ENSG00000127616 E064 36.4028010 0.0003954858 9.034549e-01 9.690196e-01 19 11021748 11021967 220 + 1.567 1.574 0.025
ENSG00000127616 E065 23.5834645 0.0005858168 4.929849e-01 7.550252e-01 19 11023518 11023631 114 + 1.405 1.364 -0.141
ENSG00000127616 E066 21.0181411 0.0006266203 4.539086e-03 4.628684e-02 19 11024331 11024438 108 + 1.412 1.225 -0.651
ENSG00000127616 E067 25.4943341 0.0006365948 2.979626e-01 5.909491e-01 19 11025422 11025508 87 + 1.446 1.385 -0.209
ENSG00000127616 E068 0.3720642 0.0166481710 4.056535e-01   19 11025509 11025619 111 + 0.082 0.197 1.462
ENSG00000127616 E069 19.9094274 0.0024284163 3.519631e-01 6.420728e-01 19 11026300 11026346 47 + 1.344 1.281 -0.219
ENSG00000127616 E070 0.0000000       19 11027732 11027783 52 +      
ENSG00000127616 E071 41.8799531 0.0003489324 9.198901e-01 9.750314e-01 19 11027784 11027950 167 + 1.630 1.627 -0.012
ENSG00000127616 E072 26.5171647 0.0005332400 6.983216e-01 8.769098e-01 19 11030730 11030798 69 + 1.446 1.424 -0.073
ENSG00000127616 E073 30.0709133 0.0005008419 9.035592e-01 9.690425e-01 19 11030799 11030893 95 + 1.486 1.494 0.027
ENSG00000127616 E074 4.3655317 0.0127551104 2.446763e-04 4.940611e-03 19 11030894 11032666 1773 + 0.459 0.928 1.993
ENSG00000127616 E075 0.7435314 0.1373434159 2.854630e-01 5.791297e-01 19 11033082 11033289 208 + 0.151 0.332 1.462
ENSG00000127616 E076 51.7464911 0.0003386587 1.891431e-01 4.677491e-01 19 11033290 11033486 197 + 1.694 1.749 0.189
ENSG00000127616 E077 16.2996480 0.0015749522 6.731575e-01 8.646266e-01 19 11033487 11033517 31 + 1.248 1.218 -0.105
ENSG00000127616 E078 0.0000000       19 11033727 11033766 40 +      
ENSG00000127616 E079 1.0954461 0.0204532697 8.911921e-01 9.637844e-01 19 11033767 11033771 5 + 0.310 0.332 0.140
ENSG00000127616 E080 1.5872470 0.1481070252 8.544342e-01 9.486887e-01 19 11033772 11033865 94 + 0.391 0.435 0.240
ENSG00000127616 E081 0.2374063 0.2443577864 4.296235e-01   19 11033866 11034122 257 + 0.151 0.000 -13.021
ENSG00000127616 E082 28.4276036 0.0055238214 6.478791e-01 8.513037e-01 19 11034123 11034200 78 + 1.452 1.482 0.101
ENSG00000127616 E083 33.6623238 0.0003964633 4.866589e-01 7.502345e-01 19 11034914 11035021 108 + 1.520 1.557 0.126
ENSG00000127616 E084 35.3528624 0.0072721138 6.461492e-01 8.502474e-01 19 11035022 11035132 111 + 1.544 1.574 0.102
ENSG00000127616 E085 3.4478748 0.0040835042 1.151298e-01 3.576438e-01 19 11039458 11039553 96 + 0.544 0.748 0.877
ENSG00000127616 E086 9.1664656 0.0014962328 9.842689e-05 2.342699e-03 19 11039554 11040495 942 + 0.808 1.170 1.347
ENSG00000127616 E087 0.2451451 0.0164789279 8.053213e-01   19 11040634 11040643 10 + 0.082 0.110 0.462
ENSG00000127616 E088 10.6142321 0.0013051844 3.808414e-11 4.034554e-09 19 11040644 11041297 654 + 0.696 1.300 2.259
ENSG00000127616 E089 4.6546030 0.0159411905 3.644549e-01 6.531820e-01 19 11041298 11041306 9 + 0.696 0.810 0.462
ENSG00000127616 E090 49.2775165 0.0004346513 1.545308e-02 1.072949e-01 19 11041307 11041438 132 + 1.649 1.754 0.355
ENSG00000127616 E091 52.3058840 0.0002777030 3.382177e-02 1.750217e-01 19 11041439 11041560 122 + 1.682 1.771 0.300
ENSG00000127616 E092 0.3629044 0.0165476116 7.995212e-01   19 11047595 11047795 201 + 0.151 0.110 -0.538
ENSG00000127616 E093 0.4986650 0.0304051333 1.934967e-01   19 11056217 11056382 166 + 0.082 0.270 2.047
ENSG00000127616 E094 12.2288827 0.0018652667 3.347546e-01 6.265940e-01 19 11058255 11058257 3 + 1.081 1.161 0.289
ENSG00000127616 E095 49.1790301 0.0003298417 1.830755e-01 4.597270e-01 19 11058258 11058363 106 + 1.671 1.729 0.197
ENSG00000127616 E096 0.3646036 0.0166428548 7.994879e-01   19 11058686 11058787 102 + 0.151 0.110 -0.538
ENSG00000127616 E097 54.9736227 0.0003327429 5.186432e-02 2.260295e-01 19 11058788 11058889 102 + 1.708 1.788 0.270
ENSG00000127616 E098 1.2323037 0.0484140669 2.823486e-01 5.760181e-01 19 11058890 11059227 338 + 0.263 0.435 1.047
ENSG00000127616 E099 67.1586874 0.0003228997 4.461393e-02 2.064221e-01 19 11059753 11059885 133 + 1.796 1.871 0.252
ENSG00000127616 E100 77.2331006 0.0002544260 1.608939e-01 4.289072e-01 19 11060045 11060187 143 + 1.868 1.917 0.165
ENSG00000127616 E101 0.0000000       19 11060461 11060502 42 +      
ENSG00000127616 E102 0.1186381 0.0118352636 7.392986e-01   19 11061743 11061783 41 + 0.082 0.000 -12.879
ENSG00000127616 E103 111.6716445 0.0001596895 3.705497e-01 6.588392e-01 19 11061784 11062468 685 + 2.037 2.063 0.088
ENSG00000127616 E104 0.4994176 0.4945580337 4.193715e-01   19 11065193 11066122 930 + 0.082 0.270 2.049
ENSG00000127616 E105 0.0000000       19 11078997 11079426 430 +      

Help

Please Click HERE to learn more details about the results from DEXseq.