ENSG00000127824

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000248437 ENSG00000127824 No_inf pgKDN_inf TUBA4A protein_coding protein_coding 67.67339 89.40581 65.43248 5.82815 2.052425 -0.4503025 3.376199 0.6429079 5.777276 0.4096945 0.7993467 3.1479330 0.0599250 0.007150 0.088275 0.081125 0.007116665 0.007116665 FALSE  
ENST00000398989 ENSG00000127824 No_inf pgKDN_inf TUBA4A protein_coding protein_coding 67.67339 89.40581 65.43248 5.82815 2.052425 -0.4503025 7.532598 12.7122086 4.587575 7.3626462 4.5875753 -1.4684041 0.1018000 0.128625 0.074100 -0.054525 0.852347339 0.007116665 FALSE  
ENST00000462806 ENSG00000127824 No_inf pgKDN_inf TUBA4A protein_coding retained_intron 67.67339 89.40581 65.43248 5.82815 2.052425 -0.4503025 9.252961 15.1052763 7.282328 0.8344717 1.3389008 -1.0515561 0.1299417 0.172725 0.109775 -0.062950 0.522500473 0.007116665 FALSE  
ENST00000498660 ENSG00000127824 No_inf pgKDN_inf TUBA4A protein_coding protein_coding_CDS_not_defined 67.67339 89.40581 65.43248 5.82815 2.052425 -0.4503025 12.320682 10.3659641 18.349111 3.5960129 6.5404378 0.8232508 0.1891917 0.120775 0.274775 0.154000 0.853263662 0.007116665 FALSE  
MSTRG.17677.3 ENSG00000127824 No_inf pgKDN_inf TUBA4A protein_coding   67.67339 89.40581 65.43248 5.82815 2.052425 -0.4503025 32.337029 45.8030508 27.224606 1.5017600 1.4331823 -0.7503176 0.4799833 0.517900 0.418725 -0.099175 0.498623689 0.007116665 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000127824 E001 0.0000000       2 219249710 219249710 1 -      
ENSG00000127824 E002 0.0000000       2 219249711 219250281 571 -      
ENSG00000127824 E003 111.6844792 0.0011963789 2.178218e-01 0.504290785 2 219250282 219250728 447 - 2.017 2.052 0.119
ENSG00000127824 E004 44.4972153 0.0003415501 3.242806e-01 0.616692354 2 219250729 219250771 43 - 1.617 1.662 0.150
ENSG00000127824 E005 131.2183025 0.0067040105 6.331178e-01 0.842958803 2 219250772 219251112 341 - 2.117 2.103 -0.049
ENSG00000127824 E006 41.7108783 0.0007386493 1.067912e-01 0.342389641 2 219251113 219251172 60 - 1.662 1.588 -0.253
ENSG00000127824 E007 32.2579127 0.0005412551 2.508454e-01 0.541972699 2 219251173 219251193 21 - 1.545 1.485 -0.205
ENSG00000127824 E008 62.7998397 0.0002905598 1.436844e-01 0.403618571 2 219251194 219251323 130 - 1.825 1.771 -0.182
ENSG00000127824 E009 12.3734017 0.0012578258 9.250551e-05 0.002229308 2 219251324 219251538 215 - 0.866 1.217 1.289
ENSG00000127824 E010 2.8816594 0.0048761816 2.185819e-02 0.134209890 2 219251539 219251564 26 - 0.344 0.679 1.644
ENSG00000127824 E011 25.4626607 0.0036909210 5.156937e-01 0.771613247 2 219251565 219251586 22 - 1.384 1.425 0.140
ENSG00000127824 E012 53.3291570 0.0026260853 6.653457e-01 0.860804490 2 219251587 219251713 127 - 1.711 1.729 0.062
ENSG00000127824 E013 4.4875068 0.0031982039 6.546597e-02 0.257688029 2 219251714 219252007 294 - 0.570 0.803 0.981
ENSG00000127824 E014 58.1715287 0.0004124842 4.037091e-01 0.686540976 2 219252008 219252230 223 - 1.779 1.747 -0.110
ENSG00000127824 E015 0.4804091 0.0153681933 1.584577e-01   2 219252697 219252778 82 - 0.280 0.079 -2.189
ENSG00000127824 E016 1.7579136 0.0075072498 3.877750e-02 0.190475949 2 219252779 219252993 215 - 0.205 0.529 1.981
ENSG00000127824 E017 0.8791623 0.0122936144 1.474131e-01 0.408790969 2 219252996 219253145 150 - 0.115 0.341 1.981
ENSG00000127824 E018 0.1268540 0.0125020412 8.288427e-01   2 219253209 219253354 146 - 0.000 0.079 8.141
ENSG00000127824 E019 11.6081080 0.0011958020 1.120685e-02 0.086685946 2 219253856 219253918 63 - 1.207 0.997 -0.756
ENSG00000127824 E020 0.4886249 0.0158827521 6.792042e-01   2 219254095 219254608 514 - 0.205 0.145 -0.604
ENSG00000127824 E021 0.0000000       2 219277814 219277902 89 -      

Help

Please Click HERE to learn more details about the results from DEXseq.