ENSG00000127995

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000297273 ENSG00000127995 No_inf pgKDN_inf CASD1 protein_coding protein_coding 10.60742 4.532646 22.30389 0.2306416 15.65049 2.296337 1.671229 0.8909064 2.1395186 0.3825702 1.0887760 1.254564 0.30311667 0.200225 0.307200 0.106975 9.788973e-01 2.511455e-05 FALSE TRUE
MSTRG.26558.6 ENSG00000127995 No_inf pgKDN_inf CASD1 protein_coding   10.60742 4.532646 22.30389 0.2306416 15.65049 2.296337 1.641898 1.2900400 2.7699890 0.8879688 1.0606215 1.096523 0.23804167 0.269525 0.289900 0.020375 9.672344e-01 2.511455e-05 TRUE TRUE
MSTRG.26558.7 ENSG00000127995 No_inf pgKDN_inf CASD1 protein_coding   10.60742 4.532646 22.30389 0.2306416 15.65049 2.296337 1.410600 1.9019207 0.3769648 0.2107254 0.3769648 -2.304748 0.28040000 0.428850 0.005450 -0.423400 2.511455e-05 2.511455e-05 TRUE TRUE
MSTRG.26558.8 ENSG00000127995 No_inf pgKDN_inf CASD1 protein_coding   10.60742 4.532646 22.30389 0.2306416 15.65049 2.296337 5.182480 0.0000000 15.5474393 0.0000000 15.5474393 10.603389 0.07484167 0.000000 0.224525 0.224525 9.601379e-01 2.511455e-05   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000127995 E001 0.0000000       7 94509219 94509299 81 +      
ENSG00000127995 E002 0.2357071 0.0158323235 0.326670632   7 94509809 94510067 259 + 0.158 0.000 -9.496
ENSG00000127995 E003 0.1272623 0.0126199804 0.430856883   7 94510068 94510070 3 + 0.000 0.105 10.432
ENSG00000127995 E004 0.7345904 0.0138143921 0.791921244 0.92050463 7 94510071 94510126 56 + 0.220 0.260 0.310
ENSG00000127995 E005 1.5898312 0.0089210999 0.911033076 0.97178698 7 94510127 94510217 91 + 0.405 0.421 0.088
ENSG00000127995 E006 0.8392211 0.2905840576 0.199673326 0.48140027 7 94517560 94517616 57 + 0.366 0.105 -2.277
ENSG00000127995 E007 0.4907023 0.0163017640 0.830827551   7 94517617 94517656 40 + 0.158 0.189 0.310
ENSG00000127995 E008 2.2037932 0.0183396655 0.664568366 0.86059139 7 94518203 94518323 121 + 0.474 0.538 0.310
ENSG00000127995 E009 0.4896974 0.0163360876 0.829598090   7 94522993 94523040 48 + 0.158 0.189 0.310
ENSG00000127995 E010 1.8491411 0.0089009540 0.236307889 0.52543134 7 94527162 94527206 45 + 0.365 0.538 0.895
ENSG00000127995 E011 1.7497936 0.0088974902 0.009887114 0.07966917 7 94528188 94528250 63 + 0.220 0.602 2.185
ENSG00000127995 E012 0.8785330 0.0126178900 0.025083619 0.14570382 7 94533205 94533249 45 + 0.086 0.421 2.895
ENSG00000127995 E013 1.5827166 0.1674318056 0.885794800 0.96172109 7 94533679 94533802 124 + 0.404 0.421 0.090
ENSG00000127995 E014 4.2940513 0.0041039601 0.418498964 0.69813254 7 94535309 94535523 215 + 0.675 0.771 0.393
ENSG00000127995 E015 9.2630032 0.0016028408 0.829561332 0.93825075 7 94537472 94537894 423 + 1.019 1.000 -0.072
ENSG00000127995 E016 3.9792973 0.0068019808 0.095928142 0.32259561 7 94538967 94539056 90 + 0.782 0.571 -0.891
ENSG00000127995 E017 4.2626499 0.0035211701 0.832863281 0.93972193 7 94544411 94544530 120 + 0.732 0.707 -0.105
ENSG00000127995 E018 5.9884358 0.0307617002 0.815244776 0.93242787 7 94545545 94545701 157 + 0.827 0.861 0.133
ENSG00000127995 E019 4.4081070 0.0042035796 0.520528838 0.77482714 7 94547096 94547175 80 + 0.695 0.771 0.310
ENSG00000127995 E020 5.0015419 0.0528883064 0.931403099 0.97999201 7 94549533 94549621 89 + 0.766 0.791 0.099
ENSG00000127995 E021 2.6639616 0.1242203021 0.555196074 0.79778462 7 94549622 94549634 13 + 0.610 0.502 -0.497
ENSG00000127995 E022 5.6871032 0.0030071138 0.134623688 0.39011358 7 94551338 94551478 141 + 0.893 0.729 -0.644
ENSG00000127995 E023 1.2060960 0.0124360639 0.346991830 0.63759394 7 94551733 94552349 617 + 0.405 0.260 -0.912
ENSG00000127995 E024 4.3722545 0.0037633228 0.483012369 0.74774790 7 94552350 94552427 78 + 0.766 0.683 -0.342
ENSG00000127995 E025 0.5992382 0.0144387597 0.258280673 0.55064076 7 94553852 94554482 631 + 0.274 0.105 -1.690
ENSG00000127995 E026 3.2903410 0.0047245626 0.985396055 0.99899506 7 94554483 94554575 93 + 0.633 0.631 -0.012
ENSG00000127995 E027 48.0740673 0.0005058319 0.774880329 0.91353184 7 94555492 94557019 1528 + 1.686 1.695 0.031

Help

Please Click HERE to learn more details about the results from DEXseq.