ENSG00000128050

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000504188 ENSG00000128050 No_inf pgKDN_inf PAICS protein_coding retained_intron 49.05647 19.60755 62.81909 0.6352954 3.021501 1.679288 1.934122 2.1847653 2.9223056 1.4119266 1.1521595 0.4179688 0.05456667 0.106450 0.045675 -0.060775 1.00000000 0.02130803    
ENST00000508554 ENSG00000128050 No_inf pgKDN_inf PAICS protein_coding retained_intron 49.05647 19.60755 62.81909 0.6352954 3.021501 1.679288 1.529388 1.5461314 0.5042798 0.3112484 0.2117949 -1.5973386 0.04170833 0.078500 0.008550 -0.069950 0.02130803 0.02130803    
ENST00000510584 ENSG00000128050 No_inf pgKDN_inf PAICS protein_coding retained_intron 49.05647 19.60755 62.81909 0.6352954 3.021501 1.679288 19.001705 3.7541421 23.1517426 1.3074956 2.6737080 2.6213508 0.34064167 0.196000 0.365375 0.169375 0.54919706 0.02130803    
ENST00000512576 ENSG00000128050 No_inf pgKDN_inf PAICS protein_coding protein_coding 49.05647 19.60755 62.81909 0.6352954 3.021501 1.679288 23.502416 11.3988405 30.1173280 0.4118754 1.8680020 1.4009205 0.50329167 0.581550 0.478625 -0.102925 0.43746136 0.02130803 FALSE  
ENST00000514888 ENSG00000128050 No_inf pgKDN_inf PAICS protein_coding protein_coding 49.05647 19.60755 62.81909 0.6352954 3.021501 1.679288 2.094868 0.4607423 5.5031575 0.4607423 1.5124920 3.5498695 0.04065000 0.024975 0.091550 0.066575 0.25176984 0.02130803 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000128050 E001 0.0000000       4 56435741 56435748 8 +      
ENSG00000128050 E002 0.0000000       4 56435749 56435751 3 +      
ENSG00000128050 E003 1.1983203 0.0102890432 6.242862e-01 0.83838111 4 56435752 56435928 177 + 0.338 0.259 -0.532
ENSG00000128050 E004 0.0000000       4 56435929 56435975 47 +      
ENSG00000128050 E005 0.0000000       4 56436039 56436137 99 +      
ENSG00000128050 E006 7.1064521 0.0268902869 9.159613e-01 0.97367709 4 56436138 56436259 122 + 0.865 0.876 0.041
ENSG00000128050 E007 3.2519197 0.0124611994 9.334482e-01 0.98082166 4 56436260 56436261 2 + 0.596 0.585 -0.047
ENSG00000128050 E008 16.4041461 0.0050316438 4.434001e-02 0.20585270 4 56436262 56436328 67 + 1.239 1.064 -0.626
ENSG00000128050 E009 0.1176306 0.0117422425 1.000000e+00   4 56436531 56436561 31 + 0.060 0.000 -9.928
ENSG00000128050 E010 55.2981879 0.0003039801 2.084828e-02 0.13015051 4 56441663 56441860 198 + 1.731 1.629 -0.348
ENSG00000128050 E011 0.4822993 0.0207596995 1.000000e+00   4 56441861 56442028 168 + 0.159 0.148 -0.117
ENSG00000128050 E012 0.1265070 0.0122229998 1.711561e-01   4 56446357 56446377 21 + 0.000 0.148 10.978
ENSG00000128050 E013 57.4469039 0.0002871885 3.043094e-01 0.59776824 4 56446695 56446873 179 + 1.732 1.690 -0.141
ENSG00000128050 E014 61.1278905 0.0020326189 5.928919e-01 0.82054323 4 56448418 56448597 180 + 1.753 1.732 -0.072
ENSG00000128050 E015 0.0000000       4 56448699 56448709 11 +      
ENSG00000128050 E016 42.9202593 0.0061711001 5.053082e-02 0.22214135 4 56448710 56448823 114 + 1.627 1.510 -0.400
ENSG00000128050 E017 39.8197600 0.0003762787 4.498410e-02 0.20731967 4 56450619 56450702 84 + 1.592 1.487 -0.359
ENSG00000128050 E018 1.3600729 0.0180284180 1.236494e-02 0.09211201 4 56450703 56451191 489 + 0.201 0.585 2.275
ENSG00000128050 E019 62.2787571 0.0002634378 2.895476e-01 0.58318253 4 56451872 56452052 181 + 1.766 1.725 -0.140
ENSG00000128050 E020 58.4501920 0.0009020869 6.463952e-01 0.85038601 4 56453603 56453761 159 + 1.721 1.745 0.078
ENSG00000128050 E021 476.3260294 0.0004632340 4.274155e-05 0.00116957 4 56459372 56464578 5207 + 2.618 2.667 0.163

Help

Please Click HERE to learn more details about the results from DEXseq.