ENSG00000128191

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000351989 ENSG00000128191 No_inf pgKDN_inf DGCR8 protein_coding protein_coding 17.11609 20.64636 13.13825 1.034775 0.6129388 -0.6517159 1.8640998 1.460485 1.8909690 1.4604847 1.8909690 0.37044322 0.12603333 0.073350 0.162250 0.088900 0.983247812 0.002855807 FALSE TRUE
ENST00000407755 ENSG00000128191 No_inf pgKDN_inf DGCR8 protein_coding protein_coding 17.11609 20.64636 13.13825 1.034775 0.6129388 -0.6517159 0.7165879 1.898671 0.0000000 1.1756582 0.0000000 -7.57642427 0.03825833 0.098500 0.000000 -0.098500 0.607285069 0.002855807 FALSE TRUE
ENST00000457069 ENSG00000128191 No_inf pgKDN_inf DGCR8 protein_coding protein_coding 17.11609 20.64636 13.13825 1.034775 0.6129388 -0.6517159 1.2110836 2.533666 0.0000000 1.5336673 0.0000000 -7.99076522 0.05989167 0.113150 0.000000 -0.113150 0.563316113 0.002855807 FALSE TRUE
ENST00000485802 ENSG00000128191 No_inf pgKDN_inf DGCR8 protein_coding retained_intron 17.11609 20.64636 13.13825 1.034775 0.6129388 -0.6517159 1.4837392 1.948886 0.0000000 0.7257891 0.0000000 -7.61388964 0.07012500 0.092525 0.000000 -0.092525 0.010160444 0.002855807 FALSE TRUE
ENST00000491892 ENSG00000128191 No_inf pgKDN_inf DGCR8 protein_coding retained_intron 17.11609 20.64636 13.13825 1.034775 0.6129388 -0.6517159 0.8494406 1.001901 0.8630294 0.4349104 0.3511087 -0.21296581 0.05111667 0.046650 0.062825 0.016175 0.939060914 0.002855807 FALSE FALSE
ENST00000498171 ENSG00000128191 No_inf pgKDN_inf DGCR8 protein_coding retained_intron 17.11609 20.64636 13.13825 1.034775 0.6129388 -0.6517159 2.6044937 3.872957 1.2001860 0.6992648 0.7320126 -1.68192690 0.14483333 0.188550 0.096150 -0.092400 0.584461438 0.002855807 FALSE TRUE
ENST00000704821 ENSG00000128191 No_inf pgKDN_inf DGCR8 protein_coding protein_coding 17.11609 20.64636 13.13825 1.034775 0.6129388 -0.6517159 1.2837944 1.563066 1.5609604 0.9464856 0.6567170 -0.00193256 0.08030833 0.075225 0.118550 0.043325 0.833651877 0.002855807 FALSE TRUE
MSTRG.19066.2 ENSG00000128191 No_inf pgKDN_inf DGCR8 protein_coding   17.11609 20.64636 13.13825 1.034775 0.6129388 -0.6517159 3.7361881 0.000000 7.0207811 0.0000000 2.3838424 9.45754117 0.24764167 0.000000 0.513925 0.513925 0.002855807 0.002855807 TRUE TRUE
MSTRG.19066.8 ENSG00000128191 No_inf pgKDN_inf DGCR8 protein_coding   17.11609 20.64636 13.13825 1.034775 0.6129388 -0.6517159 1.9236660 4.346209 0.2823987 0.4529860 0.1345186 -3.89706457 0.10094167 0.214350 0.023075 -0.191275 0.003759116 0.002855807 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000128191 E001 0.0000000       22 20080221 20080240 20 +      
ENSG00000128191 E002 0.3611417 0.0165466979 3.500756e-01   22 20080241 20080281 41 + 0.204 0.079 -1.593
ENSG00000128191 E003 0.3611417 0.0165466979 3.500756e-01   22 20080282 20080288 7 + 0.204 0.079 -1.593
ENSG00000128191 E004 2.1929122 0.0071438799 1.699919e-01 4.420747e-01 22 20080289 20080383 95 + 0.603 0.414 -0.915
ENSG00000128191 E005 0.4983826 0.0236025996 5.722821e-01   22 20080569 20080685 117 + 0.114 0.204 0.992
ENSG00000128191 E006 1.7048515 0.0080800633 1.835931e-01 4.604421e-01 22 20085687 20085695 9 + 0.532 0.342 -1.008
ENSG00000128191 E007 2.8023839 0.0052259892 1.002450e-01 3.307809e-01 22 20085696 20085745 50 + 0.691 0.476 -0.971
ENSG00000128191 E008 3.9240784 0.0320574944 2.806274e-01 5.739317e-01 22 20085746 20085819 74 + 0.764 0.622 -0.593
ENSG00000128191 E009 13.3002366 0.0044345140 5.049070e-01 7.638639e-01 22 20085820 20086057 238 + 1.171 1.126 -0.162
ENSG00000128191 E010 5.0185952 0.0055524759 1.309921e-01 3.839634e-01 22 20086058 20086104 47 + 0.864 0.698 -0.663
ENSG00000128191 E011 18.7176218 0.0011041135 3.387441e-03 3.785707e-02 22 20086105 20086533 429 + 1.388 1.203 -0.649
ENSG00000128191 E012 15.3850617 0.0009284462 4.822673e-01 7.471950e-01 22 20086534 20086683 150 + 1.229 1.186 -0.151
ENSG00000128191 E013 6.5541103 0.0022574074 1.458487e-06 6.437155e-05 22 20086684 20087035 352 + 0.398 1.016 2.640
ENSG00000128191 E014 2.6640156 0.0085206840 1.266446e-05 4.187890e-04 22 20087036 20087161 126 + 0.000 0.715 14.174
ENSG00000128191 E015 21.4957621 0.0013315789 7.021889e-01 8.788406e-01 22 20087162 20087321 160 + 1.319 1.353 0.118
ENSG00000128191 E016 13.5062171 0.0020603792 1.382621e-01 3.956295e-01 22 20089669 20089811 143 + 1.213 1.106 -0.382
ENSG00000128191 E017 2.7315742 0.0056616205 4.689283e-01 7.370187e-01 22 20089812 20089975 164 + 0.492 0.601 0.507
ENSG00000128191 E018 23.2014527 0.0054981170 8.843354e-01 9.610847e-01 22 20089976 20090258 283 + 1.372 1.371 -0.001
ENSG00000128191 E019 21.3198069 0.0024455092 5.466678e-01 7.923487e-01 22 20091435 20091632 198 + 1.355 1.325 -0.104
ENSG00000128191 E020 13.8061573 0.0013094478 7.074112e-01 8.812835e-01 22 20091869 20091970 102 + 1.171 1.151 -0.072
ENSG00000128191 E021 13.1634698 0.0012032288 4.413325e-01 7.168375e-01 22 20092809 20092907 99 + 1.171 1.119 -0.185
ENSG00000128191 E022 0.0000000       22 20094712 20094712 1 +      
ENSG00000128191 E023 13.7841473 0.0183771214 6.608609e-01 8.584714e-01 22 20094713 20094795 83 + 1.180 1.145 -0.125
ENSG00000128191 E024 6.1479340 0.0040884671 5.096044e-01 7.674374e-01 22 20106177 20106181 5 + 0.882 0.818 -0.245
ENSG00000128191 E025 11.6357613 0.0014651298 3.970947e-01 6.814558e-01 22 20106182 20106277 96 + 1.038 1.119 0.294
ENSG00000128191 E026 0.0000000       22 20106567 20106591 25 +      
ENSG00000128191 E027 13.1420639 0.0011988531 1.762945e-01 4.504366e-01 22 20106592 20106685 94 + 1.061 1.180 0.428
ENSG00000128191 E028 7.7805224 0.0031572012 8.404933e-01 9.427691e-01 22 20106686 20106698 13 + 0.915 0.943 0.108
ENSG00000128191 E029 1.4784615 0.0099813558 8.706109e-01 9.554109e-01 22 20106699 20107036 338 + 0.398 0.379 -0.107
ENSG00000128191 E030 18.3445961 0.0011582154 4.608832e-01 7.319790e-01 22 20107271 20107398 128 + 1.300 1.259 -0.144
ENSG00000128191 E031 0.6347396 0.0148456273 6.246129e-02 2.511390e-01 22 20107399 20107571 173 + 0.000 0.300 12.435
ENSG00000128191 E032 5.2646856 0.0032575917 1.524123e-03 2.073192e-02 22 20107572 20108889 1318 + 0.492 0.902 1.729
ENSG00000128191 E033 16.5432728 0.0014529091 9.023066e-01 9.687547e-01 22 20108890 20109003 114 + 1.221 1.239 0.064
ENSG00000128191 E034 0.7614676 0.0138093151 3.476544e-02 1.781848e-01 22 20109004 20109184 181 + 0.000 0.342 12.669
ENSG00000128191 E035 93.7094728 0.0032071906 1.931563e-01 4.729759e-01 22 20110025 20111726 1702 + 1.930 1.984 0.179
ENSG00000128191 E036 1.7424631 0.0081761221 4.053745e-01 6.881581e-01 22 20111727 20111877 151 + 0.343 0.476 0.729
ENSG00000128191 E037 0.2356421 0.0156359357 1.262145e-01   22 20137872 20137929 58 + 0.204 0.000 -12.807

Help

Please Click HERE to learn more details about the results from DEXseq.