ENSG00000128294

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000398110 ENSG00000128294 No_inf pgKDN_inf TPST2 protein_coding protein_coding 133.4665 94.33104 158.5013 1.408587 1.571422 0.748628 99.473180 68.590477 120.874931 1.223497 1.6978913 0.8173439 0.74281667 0.727250 0.762775 0.035525 0.680481003 0.001335219 FALSE  
ENST00000450022 ENSG00000128294 No_inf pgKDN_inf TPST2 protein_coding protein_coding 133.4665 94.33104 158.5013 1.408587 1.571422 0.748628 17.968530 8.103270 22.994226 1.429636 1.2602931 1.5035436 0.12839167 0.085775 0.144950 0.059175 0.311408297 0.001335219    
MSTRG.19180.5 ENSG00000128294 No_inf pgKDN_inf TPST2 protein_coding   133.4665 94.33104 158.5013 1.408587 1.571422 0.748628 6.426719 8.858767 4.208863 0.334197 0.2565497 -1.0718792 0.05424167 0.093975 0.026600 -0.067375 0.001335219 0.001335219 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000128294 E001 39.9201703 0.0081639548 4.360313e-06 1.671422e-04 22 26521996 26524081 2086 - 1.467 1.739 0.925
ENSG00000128294 E002 55.7533458 0.0002933484 2.075504e-02 1.298098e-01 22 26524082 26525745 1664 - 1.710 1.798 0.295
ENSG00000128294 E003 13.1182904 0.0233767946 4.651308e-01 7.343486e-01 22 26525746 26525813 68 - 1.181 1.101 -0.287
ENSG00000128294 E004 340.5087905 0.0019489254 6.121931e-01 8.312665e-01 22 26525814 26526267 454 - 2.529 2.534 0.017
ENSG00000128294 E005 68.0971860 0.0002428205 5.308847e-39 4.473865e-36 22 26526268 26528213 1946 - 1.555 2.039 1.636
ENSG00000128294 E006 82.1649299 0.0022319414 6.452829e-01 8.498610e-01 22 26528214 26528262 49 - 1.927 1.905 -0.075
ENSG00000128294 E007 87.2416932 0.0001933071 7.554894e-01 9.036081e-01 22 26532695 26532745 51 - 1.941 1.946 0.016
ENSG00000128294 E008 3.0975062 0.0112025896 1.256745e-02 9.317621e-02 22 26532746 26533077 332 - 0.430 0.765 1.509
ENSG00000128294 E009 3.4652771 0.0058058465 2.255931e-02 1.366633e-01 22 26535895 26536287 393 - 0.493 0.785 1.269
ENSG00000128294 E010 146.0833339 0.0001987104 3.242001e-01 6.166822e-01 22 26536288 26536486 199 - 2.156 2.175 0.063
ENSG00000128294 E011 290.2899860 0.0034135825 3.075638e-03 3.514438e-02 22 26540789 26541205 417 - 2.496 2.414 -0.274
ENSG00000128294 E012 135.2163252 0.0001226965 1.566655e-02 1.082588e-01 22 26541206 26541438 233 - 2.160 2.093 -0.224
ENSG00000128294 E013 51.2124142 0.0002739060 5.719471e-02 2.390164e-01 22 26541439 26541484 46 - 1.751 1.666 -0.290
ENSG00000128294 E014 37.6953046 0.0003788723 2.809869e-02 1.566855e-01 22 26541485 26541489 5 - 1.632 1.519 -0.388
ENSG00000128294 E015 88.3829634 0.0014123889 6.693372e-05 1.691660e-03 22 26541490 26541718 229 - 2.008 1.861 -0.493
ENSG00000128294 E016 0.6082980 0.0209812978 9.129658e-01 9.723616e-01 22 26543108 26543277 170 - 0.213 0.195 -0.164
ENSG00000128294 E017 40.1507339 0.0003698048 5.028610e-02 2.215793e-01 22 26544604 26544675 72 - 1.653 1.554 -0.337
ENSG00000128294 E018 0.9736308 0.0155778342 7.792915e-01 9.149984e-01 22 26547500 26547618 119 - 0.313 0.267 -0.316
ENSG00000128294 E019 0.0000000       22 26550592 26550653 62 -      
ENSG00000128294 E020 0.1186381 0.0118395441 7.291357e-01   22 26565224 26565368 145 - 0.083 0.000 -8.693
ENSG00000128294 E021 0.6155403 0.0143128961 4.346215e-01 7.118179e-01 22 26565447 26565726 280 - 0.153 0.267 1.006
ENSG00000128294 E022 27.2902687 0.0005019433 9.067877e-02 3.127426e-01 22 26590053 26590132 80 - 1.492 1.389 -0.353
ENSG00000128294 E023 0.0000000       22 26596627 26596717 91 -      

Help

Please Click HERE to learn more details about the results from DEXseq.