ENSG00000128829

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000263791 ENSG00000128829 No_inf pgKDN_inf EIF2AK4 protein_coding protein_coding 16.02302 17.02001 17.24776 1.44366 0.9688478 0.01916614 9.1641034 7.464747 11.3509083 0.2704753 0.9712411 0.6039816 0.58238333 0.451425 0.654800 0.203375 0.23410115 0.01393678 FALSE TRUE
ENST00000558557 ENSG00000128829 No_inf pgKDN_inf EIF2AK4 protein_coding retained_intron 16.02302 17.02001 17.24776 1.44366 0.9688478 0.01916614 2.9401423 3.546153 2.7304784 0.5745946 0.9144446 -0.3758894 0.18013333 0.220625 0.151500 -0.069125 0.83616134 0.01393678 FALSE TRUE
ENST00000558823 ENSG00000128829 No_inf pgKDN_inf EIF2AK4 protein_coding protein_coding 16.02302 17.02001 17.24776 1.44366 0.9688478 0.01916614 1.6324161 4.740457 0.0000000 1.8395560 0.0000000 -8.8919224 0.08933333 0.255150 0.000000 -0.255150 0.01393678 0.01393678   FALSE
ENST00000560855 ENSG00000128829 No_inf pgKDN_inf EIF2AK4 protein_coding protein_coding 16.02302 17.02001 17.24776 1.44366 0.9688478 0.01916614 0.7367167 0.000000 0.7917547 0.0000000 0.7917547 6.3250889 0.05290000 0.000000 0.053975 0.053975 0.84732851 0.01393678 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000128829 E001 0.0000000       15 39934115 39934145 31 +      
ENSG00000128829 E002 0.8449476 0.0138559603 4.124889e-01 0.693754078 15 39934146 39934175 30 + 0.318 0.192 -0.961
ENSG00000128829 E003 4.1184469 0.0037314530 3.168938e-01 0.609705329 15 39934176 39934339 164 + 0.760 0.636 -0.513
ENSG00000128829 E004 7.3099696 0.0022324446 9.402106e-01 0.983035673 15 39939505 39939617 113 + 0.921 0.914 -0.026
ENSG00000128829 E005 7.6937818 0.0017299651 7.254916e-01 0.889823352 15 39943383 39943485 103 + 0.921 0.956 0.132
ENSG00000128829 E006 0.0000000       15 39946589 39946895 307 +      
ENSG00000128829 E007 9.8304274 0.0014300542 3.128059e-01 0.606169576 15 39949116 39949268 153 + 1.072 0.982 -0.329
ENSG00000128829 E008 7.8966760 0.0059919228 5.449302e-01 0.791082024 15 39953904 39953974 71 + 0.974 0.914 -0.224
ENSG00000128829 E009 5.8691357 0.0025660012 5.720598e-01 0.808170399 15 39953975 39953984 10 + 0.806 0.868 0.241
ENSG00000128829 E010 11.6254752 0.0190592929 4.503017e-01 0.723726752 15 39955620 39955768 149 + 1.064 1.139 0.270
ENSG00000128829 E011 8.0714456 0.0276286018 2.773820e-02 0.155399636 15 39961784 39961899 116 + 1.056 0.797 -0.976
ENSG00000128829 E012 12.3801453 0.0013255186 1.803529e-01 0.455844234 15 39965686 39965843 158 + 1.171 1.062 -0.391
ENSG00000128829 E013 25.2100189 0.0005654927 7.021395e-01 0.878840590 15 39967344 39967879 536 + 1.427 1.405 -0.074
ENSG00000128829 E014 6.5330089 0.0182790998 2.359336e-01 0.525288625 15 39972908 39973014 107 + 0.932 0.797 -0.520
ENSG00000128829 E015 8.8358292 0.0016083858 9.709176e-02 0.324521754 15 39973592 39973749 158 + 1.056 0.900 -0.580
ENSG00000128829 E016 1.2340051 0.0162691097 3.123752e-01 0.605812513 15 39973750 39975429 1680 + 0.270 0.426 0.946
ENSG00000128829 E017 17.0878792 0.0008303361 4.286272e-02 0.201829762 15 39976414 39976844 431 + 1.315 1.172 -0.503
ENSG00000128829 E018 4.2083554 0.0033710391 2.786775e-02 0.155883674 15 39976979 39978077 1099 + 0.821 0.544 -1.170
ENSG00000128829 E019 5.3494390 0.0026462279 6.990229e-01 0.877395975 15 39978078 39978147 70 + 0.821 0.778 -0.170
ENSG00000128829 E020 0.1265070 0.0122283133 4.183312e-01   15 39978148 39978292 145 + 0.000 0.106 11.109
ENSG00000128829 E021 7.7960614 0.0043841232 9.931461e-01 1.000000000 15 39985805 39985888 84 + 0.943 0.943 -0.002
ENSG00000128829 E022 8.8107618 0.0037825405 4.216114e-01 0.700788647 15 39987983 39988105 123 + 0.954 1.030 0.281
ENSG00000128829 E023 6.2563324 0.0068990893 3.222792e-01 0.615328662 15 39990273 39990377 105 + 0.806 0.914 0.417
ENSG00000128829 E024 0.2444846 0.0162396500 8.468767e-01   15 39991166 39992174 1009 + 0.085 0.106 0.361
ENSG00000128829 E025 5.1973818 0.0076980868 7.690530e-02 0.283552792 15 39992175 39992229 55 + 0.874 0.663 -0.846
ENSG00000128829 E026 0.1187032 0.0118734923 6.884727e-01   15 39992230 39992768 539 + 0.085 0.000 -11.308
ENSG00000128829 E027 7.0268568 0.0021509187 1.506776e-01 0.413338267 15 39992769 39992848 80 + 0.964 0.816 -0.565
ENSG00000128829 E028 10.0841626 0.0018947916 3.336692e-01 0.625659408 15 39996964 39997065 102 + 1.080 0.995 -0.311
ENSG00000128829 E029 8.5621508 0.0218645327 6.399512e-01 0.846992567 15 39998731 39998784 54 + 0.954 1.007 0.195
ENSG00000128829 E030 17.8873140 0.0032860897 4.739575e-01 0.740789512 15 40000988 40001224 237 + 1.296 1.247 -0.175
ENSG00000128829 E031 0.0000000       15 40002391 40002510 120 +      
ENSG00000128829 E032 0.1272623 0.0123215352 4.182705e-01   15 40002511 40002712 202 + 0.000 0.106 11.109
ENSG00000128829 E033 8.3571653 0.0072413315 1.449718e-01 0.405334933 15 40002713 40002788 76 + 1.030 0.884 -0.546
ENSG00000128829 E034 12.7532947 0.0011887237 3.234672e-01 0.616157404 15 40003193 40003314 122 + 1.171 1.092 -0.281
ENSG00000128829 E035 10.1062820 0.0023430719 7.685700e-01 0.910533815 15 40007016 40007065 50 + 1.056 1.030 -0.095
ENSG00000128829 E036 21.4746266 0.0007065915 7.722443e-01 0.912292682 15 40008027 40008195 169 + 1.341 1.360 0.065
ENSG00000128829 E037 16.7779741 0.0009833044 1.715287e-01 0.444094289 15 40009614 40009730 117 + 1.201 1.298 0.340
ENSG00000128829 E038 12.9465797 0.0014166697 6.210960e-01 0.836392821 15 40011281 40011346 66 + 1.124 1.164 0.143
ENSG00000128829 E039 19.9096132 0.0006957291 5.695257e-01 0.806426922 15 40016502 40016672 171 + 1.301 1.339 0.130
ENSG00000128829 E040 18.0359786 0.0008208935 7.597395e-01 0.905762517 15 40017108 40017242 135 + 1.287 1.267 -0.071
ENSG00000128829 E041 14.7718700 0.0010280521 7.155679e-01 0.885325876 15 40019093 40019200 108 + 1.183 1.211 0.098
ENSG00000128829 E042 0.6167661 0.0147381104 4.711725e-01 0.738640863 15 40020526 40020898 373 + 0.156 0.263 0.946
ENSG00000128829 E043 16.9234561 0.0027530512 6.328434e-01 0.842777535 15 40020899 40021027 129 + 1.267 1.233 -0.121
ENSG00000128829 E044 0.0000000       15 40021543 40022518 976 +      
ENSG00000128829 E045 12.4629092 0.0437884939 6.654489e-01 0.860821878 15 40022519 40022605 87 + 1.102 1.156 0.191
ENSG00000128829 E046 16.0445692 0.0009482005 3.021774e-01 0.595359551 15 40025977 40026089 113 + 1.262 1.188 -0.261
ENSG00000128829 E047 13.3630111 0.0009960006 3.153453e-01 0.608259474 15 40029406 40029464 59 + 1.190 1.112 -0.279
ENSG00000128829 E048 8.8104797 0.0147159740 3.477399e-01 0.638348833 15 40030359 40030392 34 + 0.943 1.041 0.361
ENSG00000128829 E049 12.2081297 0.0100464017 5.597765e-01 0.800651955 15 40030393 40030456 64 + 1.095 1.147 0.188
ENSG00000128829 E050 11.5341760 0.0020516022 7.234759e-02 0.272859715 15 40032169 40032237 69 + 1.021 1.172 0.545
ENSG00000128829 E051 11.3820609 0.0202314017 3.931784e-01 0.678177161 15 40032757 40032801 45 + 1.047 1.139 0.330
ENSG00000128829 E052 20.5675557 0.0007932742 1.057750e-01 0.340406200 15 40034326 40034444 119 + 1.282 1.386 0.361
ENSG00000128829 E053 46.2890687 0.0003443599 8.652855e-05 0.002109779 15 40035027 40035660 634 + 1.589 1.756 0.568

Help

Please Click HERE to learn more details about the results from DEXseq.