ENSG00000128989

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000249822 ENSG00000128989 No_inf pgKDN_inf ARPP19 protein_coding protein_coding 33.35055 26.95558 42.28084 1.923427 1.65026 0.649226 22.812389 17.6909653 24.110392 3.0807159 1.3193651 0.4464253 0.6962250 0.646700 0.573175 -0.073525 0.82580159 0.02128121 FALSE FALSE
ENST00000564163 ENSG00000128989 No_inf pgKDN_inf ARPP19 protein_coding protein_coding 33.35055 26.95558 42.28084 1.923427 1.65026 0.649226 1.571726 0.1786684 3.451136 0.1786684 0.3877955 4.1973208 0.0415500 0.006850 0.082525 0.075675 0.02128121 0.02128121 FALSE TRUE
ENST00000566423 ENSG00000128989 No_inf pgKDN_inf ARPP19 protein_coding protein_coding 33.35055 26.95558 42.28084 1.923427 1.65026 0.649226 5.872274 5.7578175 10.795786 2.6503053 1.6496020 0.9057065 0.1733667 0.232775 0.255400 0.022625 0.85320303 0.02128121 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000128989 E001 430.2458444 0.0001025555 3.034106e-08 1.962128e-06 15 52547045 52549526 2482 - 2.604 2.664 0.200
ENSG00000128989 E002 191.0761483 0.0001099672 2.129054e-03 2.679148e-02 15 52549527 52551260 1734 - 2.306 2.245 -0.204
ENSG00000128989 E003 18.9904804 0.0008994071 9.795948e-01 9.975919e-01 15 52551261 52551366 106 - 1.299 1.297 -0.004
ENSG00000128989 E004 31.3222641 0.0005546228 1.872985e-01 4.653472e-01 15 52551367 52551593 227 - 1.536 1.466 -0.240
ENSG00000128989 E005 16.2193497 0.0013139660 5.341723e-01 7.843635e-01 15 52551594 52551648 55 - 1.213 1.258 0.160
ENSG00000128989 E006 16.0500648 0.0008811388 7.277092e-01 8.913193e-01 15 52551649 52551671 23 - 1.240 1.215 -0.087
ENSG00000128989 E007 20.1932355 0.0007124281 7.071684e-01 8.811693e-01 15 52551672 52551734 63 - 1.334 1.310 -0.084
ENSG00000128989 E008 14.7345098 0.0042649570 8.200664e-01 9.346424e-01 15 52551735 52551768 34 - 1.202 1.184 -0.063
ENSG00000128989 E009 15.2599059 0.0009039541 4.731455e-01 7.401853e-01 15 52551769 52551808 40 - 1.184 1.237 0.189
ENSG00000128989 E010 26.6528184 0.0005781008 8.674306e-02 3.052790e-01 15 52551809 52551919 111 - 1.393 1.491 0.337
ENSG00000128989 E011 24.2763772 0.0006507290 2.617885e-01 5.545462e-01 15 52551920 52552008 89 - 1.428 1.361 -0.232
ENSG00000128989 E012 28.8172575 0.0005009815 1.186365e-02 8.986711e-02 15 52552009 52552104 96 - 1.528 1.387 -0.484
ENSG00000128989 E013 0.0000000       15 52556997 52557099 103 -      
ENSG00000128989 E014 25.9424491 0.0012223008 4.264130e-02 2.012792e-01 15 52557100 52557222 123 - 1.477 1.356 -0.417
ENSG00000128989 E015 1.6300522 0.0715091362 4.742911e-03 4.770686e-02 15 52557223 52557744 522 - 0.152 0.617 2.903
ENSG00000128989 E016 1.6787267 0.0080566598 1.017826e-01 3.332246e-01 15 52564190 52564246 57 - 0.520 0.269 -1.431
ENSG00000128989 E017 0.8557142 0.0775513381 9.774483e-01 9.965915e-01 15 52568289 52568847 559 - 0.265 0.269 0.028
ENSG00000128989 E018 8.5614384 0.0017345703 1.390850e-02 9.956743e-02 15 52568848 52568900 53 - 1.068 0.827 -0.907
ENSG00000128989 E019 4.9158498 0.0062547712 2.446546e-03 2.963083e-02 15 52568901 52568902 2 - 0.899 0.516 -1.601
ENSG00000128989 E020 7.8695020 0.0017832205 1.613465e-01 4.294030e-01 15 52568903 52569030 128 - 1.001 0.862 -0.523
ENSG00000128989 E021 0.1186381 0.0117955242 7.307343e-01   15 52569112 52569115 4 - 0.083 0.000 -8.956
ENSG00000128989 E022 3.8596439 0.0124282427 1.099808e-01 3.480759e-01 15 52569116 52569221 106 - 0.766 0.553 -0.910
ENSG00000128989 E023 0.1170040 0.0116776638 7.307103e-01   15 52569222 52569239 18 - 0.083 0.000 -8.958
ENSG00000128989 E024 0.0000000       15 52569722 52569883 162 -      

Help

Please Click HERE to learn more details about the results from DEXseq.