ENSG00000129071

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000249910 ENSG00000129071 No_inf pgKDN_inf MBD4 protein_coding protein_coding 20.53426 23.87727 17.39352 0.579155 0.7234362 -0.4568623 1.3304046 2.275260 0.2236094 1.5195790 0.2236094 -3.2901879 0.06346667 0.097325 0.012025 -0.085300 8.195332e-01 4.263102e-05 FALSE TRUE
ENST00000503197 ENSG00000129071 No_inf pgKDN_inf MBD4 protein_coding protein_coding 20.53426 23.87727 17.39352 0.579155 0.7234362 -0.4568623 1.5169940 1.029484 2.1599086 1.0294837 1.6895187 1.0617671 0.07438333 0.040200 0.121275 0.081075 8.015404e-01 4.263102e-05 FALSE TRUE
ENST00000509587 ENSG00000129071 No_inf pgKDN_inf MBD4 protein_coding protein_coding_CDS_not_defined 20.53426 23.87727 17.39352 0.579155 0.7234362 -0.4568623 0.4565603 1.369681 0.0000000 0.5281005 0.0000000 -7.1081907 0.01925000 0.057750 0.000000 -0.057750 1.276632e-01 4.263102e-05   TRUE
ENST00000515266 ENSG00000129071 No_inf pgKDN_inf MBD4 protein_coding retained_intron 20.53426 23.87727 17.39352 0.579155 0.7234362 -0.4568623 2.0113003 4.251527 0.0000000 1.0547254 0.0000000 -8.7352267 0.08669167 0.176000 0.000000 -0.176000 4.263102e-05 4.263102e-05 FALSE FALSE
MSTRG.20777.4 ENSG00000129071 No_inf pgKDN_inf MBD4 protein_coding   20.53426 23.87727 17.39352 0.579155 0.7234362 -0.4568623 9.8102404 8.935026 10.2933649 1.5740631 0.3922108 0.2039579 0.49321667 0.376750 0.594550 0.217800 2.805668e-01 4.263102e-05 FALSE TRUE
MSTRG.20777.8 ENSG00000129071 No_inf pgKDN_inf MBD4 protein_coding   20.53426 23.87727 17.39352 0.579155 0.7234362 -0.4568623 3.1294935 3.726118 3.2177867 0.4468619 1.1118447 -0.2109946 0.15508333 0.156975 0.189800 0.032825 1.000000e+00 4.263102e-05 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000129071 E001 0.000000       3 129430947 129430949 3 -      
ENSG00000129071 E002 0.000000       3 129430950 129430951 2 -      
ENSG00000129071 E003 1.133623 0.0113319502 0.039877412 0.19353451 3 129430952 129431141 190 - 0.108 0.431 2.588
ENSG00000129071 E004 2.476543 0.0058322372 0.484658024 0.74874813 3 129431142 129431265 124 - 0.474 0.575 0.481
ENSG00000129071 E005 16.073836 0.0012626326 0.121070454 0.36822489 3 129431266 129431454 189 - 1.154 1.270 0.408
ENSG00000129071 E006 21.219112 0.0008134150 0.202745251 0.48526060 3 129431455 129431578 124 - 1.383 1.308 -0.262
ENSG00000129071 E007 7.660965 0.0173904499 0.413585181 0.69427318 3 129431991 129432175 185 - 0.875 0.967 0.350
ENSG00000129071 E008 8.489383 0.0358812573 0.942919146 0.98412031 3 129432176 129432502 327 - 0.976 0.967 -0.034
ENSG00000129071 E009 8.069881 0.0018111682 0.150148078 0.41262651 3 129432503 129432532 30 - 1.025 0.891 -0.500
ENSG00000129071 E010 6.009214 0.0050073620 0.558557650 0.80014897 3 129432533 129432555 23 - 0.875 0.814 -0.236
ENSG00000129071 E011 4.658355 0.0035184909 0.566130608 0.80455556 3 129432556 129432576 21 - 0.784 0.720 -0.260
ENSG00000129071 E012 3.082303 0.0087087368 0.787596921 0.91856787 3 129432577 129432606 30 - 0.582 0.621 0.172
ENSG00000129071 E013 1.569212 0.0124380432 0.057764275 0.24046453 3 129433098 129433247 150 - 0.549 0.267 -1.582
ENSG00000129071 E014 1.115399 0.0130540998 0.569510967 0.80642692 3 129433248 129433553 306 - 0.267 0.357 0.587
ENSG00000129071 E015 3.286813 0.0046704461 0.087691722 0.30691534 3 129433850 129433858 9 - 0.742 0.523 -0.953
ENSG00000129071 E016 16.747029 0.0008118092 0.983768318 0.99869026 3 129433859 129433984 126 - 1.240 1.244 0.015
ENSG00000129071 E017 1.268942 0.0104479624 0.002028353 0.02581339 3 129433985 129434061 77 - 0.000 0.494 11.341
ENSG00000129071 E018 15.240554 0.0010158114 0.578113097 0.81148077 3 129434062 129434133 72 - 1.226 1.188 -0.132
ENSG00000129071 E019 7.495245 0.0019522073 0.616646247 0.83385440 3 129434134 129434136 3 - 0.950 0.903 -0.175
ENSG00000129071 E020 1.842906 0.0199727494 0.762750801 0.90742831 3 129436443 129436460 18 - 0.474 0.431 -0.220
ENSG00000129071 E021 56.773213 0.0003789625 0.999805113 1.00000000 3 129436461 129437046 586 - 1.753 1.756 0.010
ENSG00000129071 E022 24.677278 0.0005729645 0.335085257 0.62688571 3 129437047 129437308 262 - 1.368 1.426 0.203
ENSG00000129071 E023 10.043009 0.0015539682 0.081660026 0.29387148 3 129437720 129437807 88 - 0.936 1.095 0.587
ENSG00000129071 E024 15.856043 0.0120056452 0.548395117 0.79346933 3 129437808 129437950 143 - 1.247 1.200 -0.166
ENSG00000129071 E025 0.000000       3 129438809 129438852 44 -      
ENSG00000129071 E026 15.018015 0.0035358217 0.881704678 0.96026870 3 129439730 129440179 450 - 1.203 1.194 -0.032

Help

Please Click HERE to learn more details about the results from DEXseq.