ENSG00000129173

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000250024 ENSG00000129173 No_inf pgKDN_inf E2F8 protein_coding protein_coding 2.987746 2.983865 2.97622 0.2747528 0.1369621 -0.003688625 1.529099 0.3000637 2.97622 0.1000807 0.1369621 3.267684 0.5070167 0.103625 1 0.896375 3.649727e-08 3.649727e-08 FALSE TRUE
ENST00000527884 ENSG00000129173 No_inf pgKDN_inf E2F8 protein_coding protein_coding 2.987746 2.983865 2.97622 0.2747528 0.1369621 -0.003688625 1.381128 2.6838015 0.00000 0.2921450 0.0000000 -8.073500 0.4706833 0.896375 0 -0.896375 6.464626e-08 3.649727e-08 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000129173 E001 0.0000000       11 19224063 19224065 3 -      
ENSG00000129173 E002 10.9327968 0.001404141 0.445387147 0.71976213 11 19224066 19224840 775 - 1.044 1.104 0.215
ENSG00000129173 E003 5.7162212 0.002675038 0.006067684 0.05695344 11 19225221 19225519 299 - 0.648 0.944 1.180
ENSG00000129173 E004 3.8044912 0.003937774 0.869868306 0.95521195 11 19225520 19225615 96 - 0.671 0.690 0.081
ENSG00000129173 E005 4.9183538 0.031194681 0.561706980 0.80186084 11 19225732 19225864 133 - 0.734 0.804 0.277
ENSG00000129173 E006 0.0000000       11 19225865 19226078 214 -      
ENSG00000129173 E007 9.3753114 0.002398629 0.095382243 0.32154172 11 19229454 19229988 535 - 0.936 1.078 0.525
ENSG00000129173 E008 2.5981083 0.006102108 0.277010692 0.57043621 11 19230241 19230328 88 - 0.472 0.620 0.688
ENSG00000129173 E009 5.0424971 0.004129373 0.649139001 0.85212603 11 19230631 19230834 204 - 0.754 0.804 0.199
ENSG00000129173 E010 2.9197962 0.006216501 0.399775206 0.68348720 11 19232234 19232371 138 - 0.648 0.536 -0.498
ENSG00000129173 E011 4.5042132 0.034261402 0.434796406 0.71186659 11 19234360 19234521 162 - 0.790 0.690 -0.404
ENSG00000129173 E012 5.2089936 0.003317326 0.037935160 0.18793009 11 19234744 19235058 315 - 0.897 0.668 -0.913
ENSG00000129173 E013 0.8443224 0.012946947 0.247420079 0.53805712 11 19237314 19237346 33 - 0.348 0.172 -1.334
ENSG00000129173 E014 1.9485825 0.008927097 0.606514582 0.82871222 11 19237347 19237470 124 - 0.507 0.432 -0.375
ENSG00000129173 E015 3.8746972 0.004612250 0.067703420 0.26262344 11 19237854 19238132 279 - 0.790 0.566 -0.945
ENSG00000129173 E016 2.0596309 0.030723700 0.243272188 0.53327273 11 19240107 19240230 124 - 0.569 0.391 -0.887
ENSG00000129173 E017 1.7976235 0.007576852 0.015556867 0.10776239 11 19240548 19240945 398 - 0.597 0.238 -2.012
ENSG00000129173 E018 0.0000000       11 19241407 19241496 90 -      
ENSG00000129173 E019 0.1271363 0.012593754 0.542059190   11 19241497 19241620 124 - 0.000 0.095 8.851

Help

Please Click HERE to learn more details about the results from DEXseq.