ENSG00000129566

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000262715 ENSG00000129566 No_inf pgKDN_inf TEP1 protein_coding protein_coding 33.1885 29.93313 22.89036 0.4686376 2.157683 -0.3868544 1.4083251 3.5702449 0.000000 0.3792573 0.0000000 -8.4839145 0.04394167 0.119125 0.000000 -0.119125 6.283356e-06 6.283356e-06 FALSE TRUE
ENST00000553365 ENSG00000129566 No_inf pgKDN_inf TEP1 protein_coding nonsense_mediated_decay 33.1885 29.93313 22.89036 0.4686376 2.157683 -0.3868544 4.0049336 6.3046027 4.020039 0.7412651 1.4018194 -0.6478980 0.14413333 0.210425 0.167925 -0.042500 8.463668e-01 6.283356e-06 TRUE TRUE
ENST00000553984 ENSG00000129566 No_inf pgKDN_inf TEP1 protein_coding protein_coding 33.1885 29.93313 22.89036 0.4686376 2.157683 -0.3868544 0.8968725 0.0000000 2.690617 0.0000000 1.7048461 8.0771455 0.03570000 0.000000 0.107100 0.107100 4.037740e-01 6.283356e-06 FALSE FALSE
ENST00000555727 ENSG00000129566 No_inf pgKDN_inf TEP1 protein_coding nonsense_mediated_decay 33.1885 29.93313 22.89036 0.4686376 2.157683 -0.3868544 1.1959812 0.0000000 1.224089 0.0000000 1.2240891 6.9473028 0.04357500 0.000000 0.057500 0.057500 8.335542e-01 6.283356e-06 TRUE TRUE
ENST00000557314 ENSG00000129566 No_inf pgKDN_inf TEP1 protein_coding nonsense_mediated_decay 33.1885 29.93313 22.89036 0.4686376 2.157683 -0.3868544 3.6604282 6.2663190 2.554832 0.1766973 1.5653894 -1.2910543 0.12014167 0.209650 0.099550 -0.110100 4.933055e-01 6.283356e-06 FALSE TRUE
MSTRG.8143.1 ENSG00000129566 No_inf pgKDN_inf TEP1 protein_coding   33.1885 29.93313 22.89036 0.4686376 2.157683 -0.3868544 1.4217090 0.6036374 1.180768 0.2805703 0.8598095 0.9564337 0.05152500 0.020500 0.058875 0.038375 9.898394e-01 6.283356e-06 TRUE TRUE
MSTRG.8143.10 ENSG00000129566 No_inf pgKDN_inf TEP1 protein_coding   33.1885 29.93313 22.89036 0.4686376 2.157683 -0.3868544 1.6587815 0.0000000 2.254244 0.0000000 1.3951649 7.8228859 0.06773333 0.000000 0.108950 0.108950 4.507280e-01 6.283356e-06 FALSE TRUE
MSTRG.8143.18 ENSG00000129566 No_inf pgKDN_inf TEP1 protein_coding   33.1885 29.93313 22.89036 0.4686376 2.157683 -0.3868544 8.3402703 0.0000000 0.000000 0.0000000 0.0000000 0.0000000 0.11708333 0.000000 0.000000 0.000000   6.283356e-06   FALSE
MSTRG.8143.4 ENSG00000129566 No_inf pgKDN_inf TEP1 protein_coding   33.1885 29.93313 22.89036 0.4686376 2.157683 -0.3868544 1.1597729 1.0910262 2.388292 0.3809262 0.8624427 1.1231588 0.04653333 0.036475 0.103125 0.066650 7.519687e-01 6.283356e-06 TRUE TRUE
MSTRG.8143.5 ENSG00000129566 No_inf pgKDN_inf TEP1 protein_coding   33.1885 29.93313 22.89036 0.4686376 2.157683 -0.3868544 7.7443799 10.4347085 5.058200 0.8174031 0.9779821 -1.0432268 0.27035000 0.348500 0.236150 -0.112350 6.304650e-01 6.283356e-06 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000129566 E001 0.1272623 0.0123550556 8.397626e-01   14 20365644 20365666 23 - 0.000 0.078 8.219
ENSG00000129566 E002 0.3625236 0.1628311985 3.925750e-01   14 20365667 20365677 11 - 0.206 0.078 -1.617
ENSG00000129566 E003 1.0972703 0.0135249800 3.381121e-01 0.6299481202 14 20365678 20365696 19 - 0.401 0.253 -0.939
ENSG00000129566 E004 135.3560552 0.0001457561 5.033376e-06 0.0001894312 14 20365697 20367103 1407 - 2.046 2.162 0.388
ENSG00000129566 E005 38.1931942 0.0003773779 4.768241e-01 0.7431809236 14 20367104 20367630 527 - 1.558 1.593 0.117
ENSG00000129566 E006 10.0907000 0.0060133364 2.635819e-02 0.1504818889 14 20367631 20367907 277 - 0.885 1.102 0.806
ENSG00000129566 E007 42.2409868 0.0003747531 3.641374e-04 0.0068050549 14 20367908 20368393 486 - 1.508 1.680 0.585
ENSG00000129566 E008 23.9211734 0.0005544759 9.460396e-02 0.3200182011 14 20368394 20368559 166 - 1.316 1.420 0.360
ENSG00000129566 E009 14.9992598 0.0009177108 1.447421e-01 0.4049444728 14 20368798 20368880 83 - 1.118 1.231 0.400
ENSG00000129566 E010 10.7609274 0.0012799929 4.616075e-01 0.7322333536 14 20368881 20368902 22 - 1.017 1.082 0.236
ENSG00000129566 E011 10.3683141 0.0022560374 7.965000e-01 0.9229378274 14 20369344 20369366 23 - 1.029 1.052 0.083
ENSG00000129566 E012 24.5212245 0.0007981623 6.229335e-01 0.8376498264 14 20369367 20369554 188 - 1.413 1.382 -0.105
ENSG00000129566 E013 8.6997315 0.0443302858 1.521161e-01 0.4158460783 14 20369555 20369576 22 - 0.849 1.037 0.705
ENSG00000129566 E014 19.0062925 0.0007596880 8.928491e-01 0.9645019754 14 20369674 20369779 106 - 1.283 1.292 0.030
ENSG00000129566 E015 19.2602969 0.0009076184 3.662062e-02 0.1841067072 14 20371218 20371314 97 - 1.375 1.236 -0.489
ENSG00000129566 E016 10.8552660 0.0012555166 9.579332e-01 0.9899059421 14 20371489 20371517 29 - 1.065 1.060 -0.019
ENSG00000129566 E017 16.7685587 0.0022774118 8.260836e-01 0.9370212864 14 20371518 20371607 90 - 1.247 1.231 -0.059
ENSG00000129566 E018 9.5011808 0.0278542677 9.340297e-01 0.9810138460 14 20371608 20371632 25 - 1.004 1.012 0.030
ENSG00000129566 E019 14.1941109 0.0339348377 9.254493e-01 0.9775781044 14 20372733 20372857 125 - 1.166 1.171 0.020
ENSG00000129566 E020 18.1283264 0.0009645096 9.924403e-01 1.0000000000 14 20373011 20373147 137 - 1.269 1.269 0.000
ENSG00000129566 E021 18.2523075 0.0015684607 2.100760e-02 0.1308877101 14 20373270 20373402 133 - 1.364 1.205 -0.559
ENSG00000129566 E022 8.8235208 0.0324103817 2.238412e-01 0.5114230846 14 20373507 20373583 77 - 1.065 0.920 -0.537
ENSG00000129566 E023 12.5888757 0.0011128412 9.539147e-01 0.9886619428 14 20373678 20373783 106 - 1.118 1.122 0.015
ENSG00000129566 E024 7.8323181 0.0018294778 5.331553e-02 0.2298224403 14 20373784 20373810 27 - 1.042 0.853 -0.708
ENSG00000129566 E025 10.6452347 0.0012850474 2.209962e-02 0.1350771752 14 20374429 20374536 108 - 1.166 0.968 -0.717
ENSG00000129566 E026 13.0741721 0.0012260797 8.226207e-01 0.9356232070 14 20375755 20375868 114 - 1.147 1.129 -0.067
ENSG00000129566 E027 15.1080340 0.0009615086 1.762263e-01 0.4503828018 14 20376104 20376264 161 - 1.255 1.153 -0.359
ENSG00000129566 E028 8.6668331 0.0016945675 3.725477e-01 0.6604322094 14 20377280 20377358 79 - 0.918 1.004 0.321
ENSG00000129566 E029 9.1830178 0.0020459893 2.135918e-01 0.4987384783 14 20377359 20377424 66 - 0.918 1.037 0.441
ENSG00000129566 E030 10.3802957 0.0019781082 7.946929e-01 0.9218006626 14 20377425 20377492 68 - 1.029 1.052 0.083
ENSG00000129566 E031 8.1290749 0.0017971132 6.306176e-01 0.8414996292 14 20377600 20377662 63 - 0.977 0.930 -0.177
ENSG00000129566 E032 8.3210616 0.0017555142 4.809845e-02 0.2158187859 14 20377663 20377753 91 - 1.065 0.876 -0.703
ENSG00000129566 E033 11.5976202 0.0012651958 5.608531e-03 0.0538335099 14 20378024 20378236 213 - 1.216 0.987 -0.831
ENSG00000129566 E034 10.8240263 0.0020596546 4.880864e-01 0.7515202099 14 20378380 20378535 156 - 1.098 1.037 -0.222
ENSG00000129566 E035 9.1981817 0.0080284657 2.358386e-01 0.5251742832 14 20378754 20378853 100 - 1.065 0.950 -0.425
ENSG00000129566 E036 11.8434312 0.0013180467 5.400383e-03 0.0523479973 14 20378981 20379105 125 - 1.224 0.995 -0.826
ENSG00000129566 E037 11.6468067 0.0017172413 8.192321e-02 0.2944862366 14 20379930 20380053 124 - 1.175 1.029 -0.526
ENSG00000129566 E038 15.0568943 0.0077834064 8.393076e-01 0.9423601997 14 20380235 20380475 241 - 1.183 1.199 0.057
ENSG00000129566 E039 8.7916687 0.0015724203 4.606412e-01 0.7319790207 14 20380931 20381045 115 - 0.933 1.004 0.262
ENSG00000129566 E040 7.9595901 0.0017410229 5.915256e-02 0.2441055652 14 20381313 20381401 89 - 0.810 1.004 0.736
ENSG00000129566 E041 4.0990486 0.0254753194 3.192873e-01 0.6119995196 14 20381553 20381686 134 - 0.606 0.744 0.584
ENSG00000129566 E042 3.0716652 0.0333558703 6.670676e-01 0.8615258763 14 20381913 20381916 4 - 0.637 0.576 -0.270
ENSG00000129566 E043 9.5511133 0.0101156140 2.376385e-01 0.5265732293 14 20381917 20382063 147 - 0.933 1.052 0.439
ENSG00000129566 E044 4.8854312 0.1157034200 5.533925e-02 0.2344040684 14 20382224 20382286 63 - 0.535 0.853 1.335
ENSG00000129566 E045 5.2247939 0.0028500120 1.433910e-01 0.4032982679 14 20382287 20382356 70 - 0.666 0.841 0.704
ENSG00000129566 E046 6.1745686 0.0107073744 8.405914e-01 0.9428145622 14 20382623 20382694 72 - 0.830 0.853 0.089
ENSG00000129566 E047 4.2091563 0.0127783744 6.328604e-01 0.8427775347 14 20382695 20382715 21 - 0.666 0.728 0.257
ENSG00000129566 E048 9.3724610 0.0030751736 8.193522e-01 0.9342779273 14 20383174 20383353 180 - 1.017 0.995 -0.080
ENSG00000129566 E049 8.7790713 0.0016302750 6.435359e-03 0.0593814613 14 20383488 20383644 157 - 1.118 0.865 -0.940
ENSG00000129566 E050 9.1655471 0.0077341779 2.234297e-02 0.1359424634 14 20383743 20383918 176 - 1.118 0.899 -0.810
ENSG00000129566 E051 9.3887535 0.0431678987 1.997060e-02 0.1269110927 14 20384038 20384232 195 - 1.157 0.876 -1.033
ENSG00000129566 E052 6.1870714 0.0023940591 6.153863e-01 0.8330948153 14 20384391 20384508 118 - 0.810 0.865 0.212
ENSG00000129566 E053 6.1334094 0.0022918008 2.277803e-01 0.5162096090 14 20384600 20384713 114 - 0.918 0.788 -0.502
ENSG00000129566 E054 6.1257966 0.0026597376 1.378414e-01 0.3950504633 14 20384985 20385109 125 - 0.933 0.774 -0.618
ENSG00000129566 E055 8.2333796 0.0188197682 3.238836e-01 0.6164945406 14 20386075 20386195 121 - 1.017 0.909 -0.402
ENSG00000129566 E056 7.9622070 0.0187279860 1.058385e-01 0.3405497985 14 20386447 20386623 177 - 1.042 0.865 -0.662
ENSG00000129566 E057 6.6678975 0.0262803605 9.312386e-01 0.9799920082 14 20387905 20388063 159 - 0.867 0.876 0.035
ENSG00000129566 E058 4.4633967 0.0043763718 4.510451e-01 0.7242254476 14 20389238 20389297 60 - 0.666 0.759 0.382
ENSG00000129566 E059 4.0669042 0.0293087263 7.646685e-01 0.9085085754 14 20389610 20389641 32 - 0.720 0.677 -0.177
ENSG00000129566 E060 5.9346713 0.0231854180 7.982162e-01 0.9240713242 14 20389642 20389740 99 - 0.810 0.841 0.119
ENSG00000129566 E061 4.2087049 0.0105607208 6.257290e-01 0.8389824142 14 20390681 20390758 78 - 0.666 0.728 0.257
ENSG00000129566 E062 8.0147953 0.0058365037 7.484043e-01 0.9006886258 14 20390938 20391096 159 - 0.963 0.930 -0.125
ENSG00000129566 E063 7.8199296 0.0411157458 3.996247e-01 0.6833813362 14 20391599 20391767 169 - 0.868 0.968 0.382
ENSG00000129566 E064 8.3805893 0.0270299804 6.702223e-01 0.8630079922 14 20395450 20395627 178 - 0.991 0.940 -0.190
ENSG00000129566 E065 5.1487632 0.0283969160 2.182690e-01 0.5047525546 14 20395859 20395949 91 - 0.867 0.712 -0.618
ENSG00000129566 E066 6.8642445 0.0029844306 1.938515e-01 0.4737021829 14 20396621 20396730 110 - 0.963 0.828 -0.515
ENSG00000129566 E067 0.1187032 0.0118098004 3.456790e-01   14 20400667 20400983 317 - 0.115 0.000 -12.564
ENSG00000129566 E068 8.4434442 0.0022628156 6.297666e-02 0.2523766971 14 20400984 20401141 158 - 1.065 0.888 -0.659
ENSG00000129566 E069 4.1500485 0.0056717000 5.922110e-02 0.2442479731 14 20401457 20401581 125 - 0.830 0.598 -0.959
ENSG00000129566 E070 4.7997386 0.0028050739 6.065761e-01 0.8287752552 14 20403377 20403448 72 - 0.789 0.728 -0.246
ENSG00000129566 E071 3.2718432 0.0043200163 1.654172e-03 0.0220613581 14 20403449 20403722 274 - 0.281 0.744 2.321
ENSG00000129566 E072 6.2916060 0.0023808555 9.683162e-01 0.9936412263 14 20403723 20403884 162 - 0.849 0.853 0.015
ENSG00000129566 E073 7.6715752 0.0079353042 5.357004e-01 0.7853253079 14 20404611 20404772 162 - 0.885 0.950 0.245
ENSG00000129566 E074 5.0246801 0.0027741474 2.337477e-01 0.5227044282 14 20405451 20405585 135 - 0.849 0.712 -0.547
ENSG00000129566 E075 2.9583685 0.0049634401 8.309643e-01 0.9388755893 14 20406233 20406285 53 - 0.606 0.576 -0.132
ENSG00000129566 E076 5.8291960 0.0062801762 2.945826e-01 0.5879575237 14 20406286 20406400 115 - 0.744 0.865 0.475
ENSG00000129566 E077 2.5954979 0.0054174274 8.965090e-01 0.9659630911 14 20407873 20407941 69 - 0.535 0.553 0.083
ENSG00000129566 E078 8.7352431 0.0016764913 4.784735e-01 0.7444822551 14 20407942 20408463 522 - 1.017 0.950 -0.250
ENSG00000129566 E079 0.2451451 0.0163365550 7.401386e-01   14 20412724 20412746 23 - 0.115 0.078 -0.618
ENSG00000129566 E080 1.2334439 0.0101526629 9.739349e-01 0.9953877330 14 20413371 20413404 34 - 0.345 0.340 -0.033
ENSG00000129566 E081 1.3588784 0.0097304184 8.331604e-01 0.9397962528 14 20413405 20413501 97 - 0.345 0.377 0.190

Help

Please Click HERE to learn more details about the results from DEXseq.