ENSG00000129625

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000379638 ENSG00000129625 No_inf pgKDN_inf REEP5 protein_coding protein_coding 137.5054 63.73206 165.2701 0.3932213 6.812092 1.374596 35.44333 28.076649 41.39531 1.862646 1.4698220 0.5599312 0.2975750 0.440925 0.250850 -0.190075 0.001924213 0.001924213 FALSE TRUE
ENST00000474542 ENSG00000129625 No_inf pgKDN_inf REEP5 protein_coding protein_coding_CDS_not_defined 137.5054 63.73206 165.2701 0.3932213 6.812092 1.374596 17.12844 5.911074 18.66563 2.060175 4.3862667 1.6572259 0.1169917 0.092625 0.111125 0.018500 0.859240284 0.001924213 FALSE FALSE
ENST00000504247 ENSG00000129625 No_inf pgKDN_inf REEP5 protein_coding protein_coding 137.5054 63.73206 165.2701 0.3932213 6.812092 1.374596 38.52527 15.130372 46.89379 1.263695 6.2584335 1.6313039 0.2697500 0.237750 0.281025 0.043275 0.812851907 0.001924213 FALSE FALSE
ENST00000511865 ENSG00000129625 No_inf pgKDN_inf REEP5 protein_coding nonsense_mediated_decay 137.5054 63.73206 165.2701 0.3932213 6.812092 1.374596 25.73913 8.767441 31.01689 1.510479 4.2158766 1.8216469 0.1778167 0.137850 0.191300 0.053450 0.751877372 0.001924213 TRUE TRUE
ENST00000513339 ENSG00000129625 No_inf pgKDN_inf REEP5 protein_coding protein_coding 137.5054 63.73206 165.2701 0.3932213 6.812092 1.374596 19.81652 5.510826 26.20922 3.633231 0.6475464 2.2476687 0.1319583 0.085550 0.159225 0.073675 0.449581926 0.001924213 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000129625 E001 227.1848943 0.0001843325 1.434547e-16 2.844517e-14 5 112876385 112878084 1700 - 2.283 2.432 0.495
ENSG00000129625 E002 75.6711478 0.0029511657 4.518299e-02 2.077939e-01 5 112878085 112878576 492 - 1.842 1.919 0.259
ENSG00000129625 E003 159.3807764 0.0023964114 1.078333e-02 8.441045e-02 5 112878577 112878832 256 - 2.221 2.144 -0.257
ENSG00000129625 E004 47.8300906 0.0003204805 4.239764e-01 7.031787e-01 5 112878833 112878835 3 - 1.691 1.653 -0.129
ENSG00000129625 E005 152.7333741 0.0007756185 5.503641e-02 2.337087e-01 5 112887015 112887183 169 - 2.194 2.142 -0.173
ENSG00000129625 E006 0.0000000       5 112892450 112892817 368 -      
ENSG00000129625 E007 134.9940000 0.0001469271 1.875638e-01 4.656846e-01 5 112902380 112902518 139 - 2.135 2.099 -0.122
ENSG00000129625 E008 93.3394534 0.0013852262 4.403813e-03 4.537063e-02 5 112921163 112921256 94 - 1.999 1.898 -0.341
ENSG00000129625 E009 0.3637832 0.1913340150 1.000000e+00   5 112921257 112921514 258 - 0.138 0.121 -0.217
ENSG00000129625 E010 0.5982308 0.0148601681 4.390321e-01 7.150462e-01 5 112921720 112922072 353 - 0.242 0.121 -1.216
ENSG00000129625 E011 86.1716291 0.0001900400 9.808051e-03 7.928382e-02 5 112922073 112922289 217 - 1.960 1.873 -0.295

Help

Please Click HERE to learn more details about the results from DEXseq.