ENSG00000129933

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000262815 ENSG00000129933 No_inf pgKDN_inf MAU2 protein_coding protein_coding 24.28902 29.50781 21.56251 1.369412 0.7795305 -0.452392 9.164279 8.395114 11.650538 1.3881645 1.3020409 0.4722950 0.39090000 0.284175 0.544475 0.260300 0.1520880750 0.0003496036 FALSE  
ENST00000587638 ENSG00000129933 No_inf pgKDN_inf MAU2 protein_coding retained_intron 24.28902 29.50781 21.56251 1.369412 0.7795305 -0.452392 1.937064 3.293684 0.515976 0.4852991 0.4257216 -2.6510069 0.07725833 0.112425 0.022300 -0.090125 0.1508956316 0.0003496036 FALSE  
ENST00000589637 ENSG00000129933 No_inf pgKDN_inf MAU2 protein_coding retained_intron 24.28902 29.50781 21.56251 1.369412 0.7795305 -0.452392 4.881936 6.130643 4.832035 0.9475615 1.2855508 -0.3427763 0.19545000 0.205600 0.219750 0.014150 1.0000000000 0.0003496036 FALSE  
ENST00000590882 ENSG00000129933 No_inf pgKDN_inf MAU2 protein_coding retained_intron 24.28902 29.50781 21.56251 1.369412 0.7795305 -0.452392 1.128237 2.604552 0.000000 0.5247167 0.0000000 -8.0304199 0.04182500 0.088300 0.000000 -0.088300 0.0003496036 0.0003496036    
MSTRG.14818.2 ENSG00000129933 No_inf pgKDN_inf MAU2 protein_coding   24.28902 29.50781 21.56251 1.369412 0.7795305 -0.452392 1.994057 1.345415 1.456690 0.9555520 0.7109670 0.1138293 0.09262500 0.047825 0.068925 0.021100 0.8357670937 0.0003496036 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000129933 E001 0.9641252 0.0182181036 7.531748e-02 0.2801691969 19 19320829 19320853 25 + 0.422 0.158 -1.906
ENSG00000129933 E002 8.3926230 0.0025546042 8.972008e-03 0.0747792090 19 19320854 19320985 132 + 1.087 0.853 -0.871
ENSG00000129933 E003 9.9062134 0.0027892286 1.384740e-01 0.3958621162 19 19320986 19321135 150 + 1.097 0.980 -0.428
ENSG00000129933 E004 0.6253605 0.1464855018 3.340817e-01 0.6259885613 19 19321525 19321903 379 + 0.105 0.273 1.678
ENSG00000129933 E005 1.6256800 0.0082032259 1.279108e-01 0.3790594875 19 19334173 19334602 430 + 0.260 0.504 1.416
ENSG00000129933 E006 4.9511146 0.0031939485 2.787917e-01 0.5720288901 19 19335718 19335735 18 + 0.684 0.826 0.572
ENSG00000129933 E007 6.2116138 0.0044759950 6.128497e-02 0.2486155520 19 19336122 19336187 66 + 0.951 0.765 -0.720
ENSG00000129933 E008 4.9797742 0.0030263056 2.640972e-02 0.1506770230 19 19337170 19337205 36 + 0.894 0.654 -0.965
ENSG00000129933 E009 6.9806254 0.0125936807 4.347650e-01 0.7118575142 19 19337206 19337265 60 + 0.937 0.866 -0.270
ENSG00000129933 E010 9.8844303 0.0014212995 2.772869e-01 0.5706527178 19 19338845 19338939 95 + 0.964 1.077 0.416
ENSG00000129933 E011 0.2545247 0.2291271851 3.988497e-01   19 19339667 19339704 38 + 0.000 0.158 11.587
ENSG00000129933 E012 5.9253055 0.0024623004 5.857105e-01 0.8161140863 19 19340846 19340873 28 + 0.792 0.866 0.289
ENSG00000129933 E013 0.0000000       19 19340874 19340876 3 +      
ENSG00000129933 E014 13.1033636 0.0010601180 2.119584e-01 0.4970332354 19 19341252 19341407 156 + 1.190 1.108 -0.294
ENSG00000129933 E015 10.4119749 0.0013921241 2.771188e-01 0.5705073981 19 19342535 19342617 83 + 1.097 1.018 -0.287
ENSG00000129933 E016 9.1709038 0.0327759337 2.639923e-01 0.5571206137 19 19342618 19342681 64 + 1.067 0.949 -0.437
ENSG00000129933 E017 11.8646746 0.0233460494 2.199112e-01 0.5065640648 19 19342776 19342866 91 + 1.167 1.053 -0.410
ENSG00000129933 E018 0.0000000       19 19342867 19342875 9 +      
ENSG00000129933 E019 10.6598719 0.0288415194 4.168330e-01 0.6966559754 19 19343837 19343940 104 + 1.106 1.027 -0.288
ENSG00000129933 E020 0.8695306 0.0124950128 4.192039e-01 0.6987591637 19 19343941 19344159 219 + 0.190 0.321 1.001
ENSG00000129933 E021 0.6345490 0.0151109452 4.109349e-02 0.1967104033 19 19344252 19344848 597 + 0.000 0.321 13.255
ENSG00000129933 E022 9.7036014 0.0016633257 7.146675e-01 0.8850514335 19 19344849 19344926 78 + 1.035 1.018 -0.065
ENSG00000129933 E023 1.3776372 0.0094438397 7.757819e-02 0.2850315502 19 19344927 19345303 377 + 0.190 0.473 1.849
ENSG00000129933 E024 10.1504340 0.0013512414 1.313717e-01 0.3845281273 19 19345304 19345369 66 + 1.106 0.989 -0.425
ENSG00000129933 E025 2.0141370 0.0080867012 7.749323e-03 0.0676626173 19 19346877 19347018 142 + 0.190 0.609 2.486
ENSG00000129933 E026 3.2764390 0.0048498763 4.308038e-04 0.0077553304 19 19347019 19347279 261 + 0.260 0.781 2.618
ENSG00000129933 E027 11.2004678 0.0011958912 6.913065e-03 0.0625901051 19 19347280 19347363 84 + 1.190 0.980 -0.764
ENSG00000129933 E028 4.3865710 0.0034376084 1.519252e-01 0.4156087907 19 19347364 19347366 3 + 0.811 0.654 -0.643
ENSG00000129933 E029 1.3563963 0.0756205591 6.583387e-01 0.8571677962 19 19347367 19347389 23 + 0.321 0.404 0.487
ENSG00000129933 E030 8.1364440 0.0017252746 7.106644e-05 0.0017786067 19 19347650 19348714 1065 + 0.659 1.093 1.679
ENSG00000129933 E031 1.6413206 0.0083279281 4.375510e-03 0.0451855560 19 19348715 19348888 174 + 0.105 0.560 3.264
ENSG00000129933 E032 5.6133421 0.0071528073 1.545240e-01 0.4199739282 19 19348889 19348897 9 + 0.894 0.748 -0.572
ENSG00000129933 E033 8.1987389 0.0026739209 2.417069e-01 0.5313755527 19 19348898 19348938 41 + 1.013 0.915 -0.364
ENSG00000129933 E034 1.7759492 0.0116993710 1.712892e-04 0.0036850058 19 19348939 19349154 216 + 0.000 0.609 14.551
ENSG00000129933 E035 12.9878075 0.0011496808 2.532584e-01 0.5448004279 19 19349155 19349232 78 + 1.183 1.108 -0.267
ENSG00000129933 E036 16.1332106 0.0008431827 4.332243e-02 0.2029650114 19 19349325 19349436 112 + 1.298 1.170 -0.452
ENSG00000129933 E037 1.0074295 0.0118514170 6.052170e-02 0.2469307524 19 19352270 19352395 126 + 0.105 0.404 2.486
ENSG00000129933 E038 11.2744915 0.0171619517 1.675262e-05 0.0005302441 19 19352398 19354203 1806 + 0.752 1.230 1.782
ENSG00000129933 E039 14.8609630 0.0034199702 6.805501e-01 0.8681671485 19 19354355 19354445 91 + 1.205 1.189 -0.058
ENSG00000129933 E040 1.1329963 0.0113139653 3.607193e-02 0.1823339918 19 19354446 19354610 165 + 0.105 0.440 2.679
ENSG00000129933 E041 1.1246216 0.1211012928 2.359435e-01 0.5252886246 19 19355143 19355263 121 + 0.190 0.404 1.486
ENSG00000129933 E042 22.7724911 0.0008828294 9.413009e-01 0.9834269230 19 19355264 19355391 128 + 1.360 1.380 0.071
ENSG00000129933 E043 356.2835417 0.0043286088 2.326994e-01 0.5213045896 19 19355708 19358774 3067 + 2.527 2.564 0.122

Help

Please Click HERE to learn more details about the results from DEXseq.