ENSG00000130021

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000381077 ENSG00000130021 No_inf pgKDN_inf PUDP protein_coding protein_coding 10.68943 9.06167 11.89184 0.7770861 0.5265528 0.3917449 7.348172 8.045451 6.700835 0.2708898 1.620416 -0.2634732 0.7235917 0.90035 0.571225 -0.329125 0.46147775 0.01919237 FALSE TRUE
MSTRG.29689.4 ENSG00000130021 No_inf pgKDN_inf PUDP protein_coding   10.68943 9.06167 11.89184 0.7770861 0.5265528 0.3917449 2.607264 0.000000 5.191007 0.0000000 1.812434 9.0226473 0.2105667 0.00000 0.428775 0.428775 0.01919237 0.01919237 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000130021 E001 0.0000000       X 6667865 6668129 265 -      
ENSG00000130021 E002 0.0000000       X 6706343 6706466 124 -      
ENSG00000130021 E003 0.1271363 0.0124228168 0.41212018   X 6721417 6721544 128 - 0.000 0.106 10.736
ENSG00000130021 E004 0.1271363 0.0124228168 0.41212018   X 6977133 6977242 110 - 0.000 0.106 10.736
ENSG00000130021 E005 0.0000000       X 6978165 6978343 179 -      
ENSG00000130021 E006 0.1268540 0.0125665467 0.41188172   X 7048920 7048929 10 - 0.000 0.106 10.736
ENSG00000130021 E007 35.8527420 0.0006286302 0.01377884 0.09895447 X 7048930 7049517 588 - 1.521 1.612 0.312
ENSG00000130021 E008 20.5356194 0.0181140456 0.19925170 0.48089796 X 7049518 7049762 245 - 1.294 1.373 0.274
ENSG00000130021 E009 37.1103395 0.0176965159 0.01253018 0.09299613 X 7049763 7050472 710 - 1.640 1.496 -0.491
ENSG00000130021 E010 0.0000000       X 7057707 7057823 117 -      
ENSG00000130021 E011 12.1305793 0.0018097130 0.17047631 0.44265897 X 7077220 7077449 230 - 1.167 1.049 -0.426
ENSG00000130021 E012 0.1268540 0.0125665467 0.41188172   X 7084751 7085471 721 - 0.000 0.106 10.736
ENSG00000130021 E013 6.1992679 0.0064460981 0.74633482 0.89967291 X 7105620 7105748 129 - 0.876 0.832 -0.173
ENSG00000130021 E014 2.4571349 0.0205037977 0.31758099 0.61031223 X 7105749 7105838 90 - 0.471 0.605 0.632
ENSG00000130021 E015 0.0000000       X 7116966 7117034 69 -      
ENSG00000130021 E016 0.1187032 0.0119801348 0.69761769   X 7142017 7142046 30 - 0.085 0.000 -10.158
ENSG00000130021 E017 0.0000000       X 7148053 7148158 106 -      

Help

Please Click HERE to learn more details about the results from DEXseq.