ENSG00000130023

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000366771 ENSG00000130023 No_inf pgKDN_inf ERMARD protein_coding retained_intron 22.61385 30.03378 18.39057 3.384296 1.485549 -0.707316 1.450940 2.326531 1.3010312 0.5213019 0.3196430 -0.833666240 0.06228333 0.081300 0.069225 -0.012075 9.513062e-01 2.767676e-05 FALSE TRUE
ENST00000366773 ENSG00000130023 No_inf pgKDN_inf ERMARD protein_coding protein_coding 22.61385 30.03378 18.39057 3.384296 1.485549 -0.707316 4.716304 1.813232 6.6394687 1.8132323 1.7358207 1.866740714 0.24525000 0.071825 0.377650 0.305825 3.390833e-02 2.767676e-05 FALSE TRUE
ENST00000392095 ENSG00000130023 No_inf pgKDN_inf ERMARD protein_coding protein_coding 22.61385 30.03378 18.39057 3.384296 1.485549 -0.707316 4.298085 5.541696 4.2118887 1.8532551 2.5206726 -0.395039908 0.19130000 0.179900 0.215475 0.035575 8.882338e-01 2.767676e-05 FALSE TRUE
ENST00000492738 ENSG00000130023 No_inf pgKDN_inf ERMARD protein_coding retained_intron 22.61385 30.03378 18.39057 3.384296 1.485549 -0.707316 1.645299 3.676896 0.1885247 1.3809655 0.1885247 -4.215015959 0.05796667 0.113425 0.008275 -0.105150 3.107841e-02 2.767676e-05   FALSE
ENST00000588451 ENSG00000130023 No_inf pgKDN_inf ERMARD protein_coding protein_coding 22.61385 30.03378 18.39057 3.384296 1.485549 -0.707316 1.137775 1.042614 0.7518879 0.7757738 0.5059207 -0.466325832 0.05402500 0.035450 0.044725 0.009275 9.528825e-01 2.767676e-05 FALSE TRUE
MSTRG.25675.13 ENSG00000130023 No_inf pgKDN_inf ERMARD protein_coding   22.61385 30.03378 18.39057 3.384296 1.485549 -0.707316 1.571543 3.839827 0.0000000 0.6271651 0.0000000 -8.588649758 0.05874167 0.129125 0.000000 -0.129125 2.767676e-05 2.767676e-05 FALSE TRUE
MSTRG.25675.14 ENSG00000130023 No_inf pgKDN_inf ERMARD protein_coding   22.61385 30.03378 18.39057 3.384296 1.485549 -0.707316 1.911086 2.079898 2.0853206 0.7395017 0.1256592 0.003738133 0.09085000 0.077075 0.116475 0.039400 7.836228e-01 2.767676e-05 TRUE TRUE
MSTRG.25675.15 ENSG00000130023 No_inf pgKDN_inf ERMARD protein_coding   22.61385 30.03378 18.39057 3.384296 1.485549 -0.707316 1.522781 3.479714 0.5183497 1.0375983 0.1762808 -2.723543526 0.05862500 0.115675 0.030725 -0.084950 5.037994e-01 2.767676e-05 FALSE TRUE
MSTRG.25675.17 ENSG00000130023 No_inf pgKDN_inf ERMARD protein_coding   22.61385 30.03378 18.39057 3.384296 1.485549 -0.707316 1.437309 2.671682 0.6578363 0.4639873 0.1748876 -2.005571572 0.05925833 0.090425 0.036075 -0.054350 5.300209e-01 2.767676e-05 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000130023 E001 0.0000000       6 169751622 169751624 3 +      
ENSG00000130023 E002 0.3527111 0.0231487629 3.623615e-02   6 169751625 169751637 13 + 0.289 0.000 -14.373
ENSG00000130023 E003 0.7086905 0.0141278320 1.406433e-03 0.019474794 6 169751638 169751647 10 + 0.461 0.000 -15.377
ENSG00000130023 E004 1.4527226 0.0191750497 4.409373e-02 0.205260749 6 169751648 169751663 16 + 0.547 0.245 -1.734
ENSG00000130023 E005 1.9739828 0.0087247063 9.835488e-01 0.998690264 6 169751797 169751937 141 + 0.461 0.462 0.003
ENSG00000130023 E006 12.5694787 0.0011413448 4.219690e-02 0.200004181 6 169752463 169753037 575 + 0.993 1.172 0.649
ENSG00000130023 E007 4.1359618 0.0035813380 1.766962e-02 0.116860021 6 169753038 169753181 144 + 0.461 0.787 1.436
ENSG00000130023 E008 2.5379783 0.0057531505 3.892915e-05 0.001074955 6 169753182 169753286 105 + 0.000 0.681 15.541
ENSG00000130023 E009 1.3939381 0.1479612350 1.182074e-02 0.089717016 6 169753287 169753316 30 + 0.000 0.490 14.678
ENSG00000130023 E010 1.2681864 0.0177904963 5.791359e-03 0.055020712 6 169753317 169753372 56 + 0.000 0.462 14.541
ENSG00000130023 E011 2.2679403 0.0073165912 1.297515e-02 0.095249999 6 169753701 169753863 163 + 0.213 0.606 2.267
ENSG00000130023 E012 4.5826386 0.0555743029 8.854299e-01 0.961460361 6 169753864 169753904 41 + 0.708 0.745 0.151
ENSG00000130023 E013 4.3307856 0.0935280139 9.262254e-01 0.977848849 6 169753905 169753943 39 + 0.708 0.714 0.025
ENSG00000130023 E014 7.2837992 0.0348548209 6.614944e-01 0.858724817 6 169753944 169754032 89 + 0.933 0.883 -0.189
ENSG00000130023 E015 4.5647864 0.0036331198 6.840106e-01 0.869235516 6 169755283 169755287 5 + 0.758 0.714 -0.181
ENSG00000130023 E016 14.2816475 0.0009732845 1.932816e-01 0.473108017 6 169755288 169755422 135 + 1.225 1.131 -0.333
ENSG00000130023 E017 1.3812559 0.3234052377 3.712641e-01 0.659308067 6 169755423 169755655 233 + 0.213 0.433 1.436
ENSG00000130023 E018 12.0847340 0.0028256887 4.745522e-01 0.741243056 6 169756338 169756439 102 + 1.134 1.080 -0.197
ENSG00000130023 E019 13.6838351 0.0010084366 4.730982e-01 0.740162011 6 169756719 169756808 90 + 1.182 1.131 -0.181
ENSG00000130023 E020 17.1183460 0.0008323556 2.506456e-01 0.541751757 6 169758968 169759065 98 + 1.182 1.271 0.314
ENSG00000130023 E021 19.8854093 0.0007185122 7.387817e-01 0.896401233 6 169759838 169759974 137 + 1.313 1.297 -0.058
ENSG00000130023 E022 18.5037056 0.0007730748 5.957768e-01 0.822268023 6 169760642 169760756 115 + 1.293 1.262 -0.108
ENSG00000130023 E023 17.2387754 0.0015028667 1.731760e-01 0.446279187 6 169762429 169762531 103 + 1.300 1.209 -0.318
ENSG00000130023 E024 5.8873026 0.0024205766 7.251599e-03 0.064613867 6 169766062 169766637 576 + 0.584 0.915 1.344
ENSG00000130023 E025 10.0177434 0.0014043196 9.690712e-01 0.993641226 6 169766638 169766667 30 + 1.020 1.029 0.032
ENSG00000130023 E026 10.4173882 0.0454580479 4.992172e-01 0.759399521 6 169767015 169768102 1088 + 0.979 1.072 0.344
ENSG00000130023 E027 12.1750651 0.0011866532 1.417308e-01 0.400550647 6 169768103 169768171 69 + 1.173 1.058 -0.412
ENSG00000130023 E028 20.9205049 0.0007044653 4.191690e-01 0.698759164 6 169769540 169769713 174 + 1.286 1.344 0.203
ENSG00000130023 E029 2.7393798 0.0690281610 3.937697e-01 0.678668527 6 169773044 169773318 275 + 0.461 0.606 0.682
ENSG00000130023 E030 16.6499496 0.0008106685 6.890196e-02 0.265193630 6 169773319 169773402 84 + 1.134 1.275 0.499
ENSG00000130023 E031 18.2800961 0.0007507397 8.809159e-01 0.959979735 6 169775270 169775346 77 + 1.271 1.266 -0.017
ENSG00000130023 E032 0.2543986 0.0160805814 4.811300e-01   6 169775878 169775939 62 + 0.000 0.140 12.219
ENSG00000130023 E033 26.1597102 0.0005959919 5.619579e-01 0.802079661 6 169775940 169776065 126 + 1.434 1.406 -0.097
ENSG00000130023 E034 0.4989181 0.0342899132 6.363459e-01   6 169776334 169776354 21 + 0.119 0.196 0.851
ENSG00000130023 E035 1.0077154 0.0114366016 1.221013e-01 0.369571533 6 169776355 169776411 57 + 0.119 0.367 2.074
ENSG00000130023 E036 18.1542617 0.0025340423 8.412773e-01 0.943054284 6 169776455 169776514 60 + 1.271 1.262 -0.033
ENSG00000130023 E037 26.2930447 0.0005663163 7.022254e-01 0.878841816 6 169776515 169776669 155 + 1.429 1.413 -0.058
ENSG00000130023 E038 8.1097928 0.0186493736 3.327472e-01 0.624898920 6 169776670 169776673 4 + 1.006 0.904 -0.382
ENSG00000130023 E039 20.7775756 0.0227234521 2.735164e-01 0.567247381 6 169779182 169779295 114 + 1.381 1.284 -0.337
ENSG00000130023 E040 14.2576588 0.0010541480 9.365093e-02 0.318211372 6 169781330 169781600 271 + 1.241 1.119 -0.434

Help

Please Click HERE to learn more details about the results from DEXseq.