ENSG00000130052

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000374597 ENSG00000130052 No_inf pgKDN_inf STARD8 protein_coding protein_coding 17.01721 13.78177 19.62156 0.3703907 0.2975152 0.5093676 7.4107935 4.936631 12.320366 1.6960687 2.3050050 1.31769726 0.42856667 0.361725 0.62945 0.267725 0.63555342 0.01153327 FALSE TRUE
ENST00000488088 ENSG00000130052 No_inf pgKDN_inf STARD8 protein_coding protein_coding_CDS_not_defined 17.01721 13.78177 19.62156 0.3703907 0.2975152 0.5093676 0.9714179 1.072325 1.097425 0.6692634 0.2852249 0.03307545 0.05739167 0.074125 0.05620 -0.017925 0.94903697 0.01153327   FALSE
MSTRG.30077.4 ENSG00000130052 No_inf pgKDN_inf STARD8 protein_coding   17.01721 13.78177 19.62156 0.3703907 0.2975152 0.5093676 2.5353772 3.953912 0.000000 1.4204137 0.0000000 -8.63078131 0.15854167 0.281375 0.00000 -0.281375 0.01153327 0.01153327 FALSE TRUE
MSTRG.30077.5 ENSG00000130052 No_inf pgKDN_inf STARD8 protein_coding   17.01721 13.78177 19.62156 0.3703907 0.2975152 0.5093676 1.7625083 2.233251 0.000000 1.3593954 0.0000000 -7.80944709 0.11110000 0.169550 0.00000 -0.169550 0.45860693 0.01153327 FALSE TRUE
MSTRG.30077.7 ENSG00000130052 No_inf pgKDN_inf STARD8 protein_coding   17.01721 13.78177 19.62156 0.3703907 0.2975152 0.5093676 4.3105088 1.505848 6.203772 1.5058475 2.3568508 2.03534470 0.24239167 0.107200 0.31435 0.207150 0.18748906 0.01153327 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000130052 E001 0.0000000       X 68647666 68647668 3 +      
ENSG00000130052 E002 0.0000000       X 68647669 68647927 259 +      
ENSG00000130052 E003 0.0000000       X 68656119 68656551 433 +      
ENSG00000130052 E004 0.0000000       X 68665499 68665532 34 +      
ENSG00000130052 E005 0.0000000       X 68685952 68685991 40 +      
ENSG00000130052 E006 0.8685892 0.2906053211 0.28512069 0.5787835 X 68693651 68693652 2 + 0.151 0.387 1.793
ENSG00000130052 E007 5.0919553 0.0027390261 0.35718262 0.6468311 X 68693653 68693826 174 + 0.820 0.726 -0.376
ENSG00000130052 E008 4.7275719 0.0469483769 0.32315099 0.6158517 X 68712914 68712985 72 + 0.807 0.676 -0.529
ENSG00000130052 E009 7.2596698 0.0022558009 0.13831843 0.3956965 X 68715294 68715375 82 + 0.969 0.830 -0.528
ENSG00000130052 E010 7.8651270 0.0021617441 0.14565183 0.4062674 X 68716368 68716431 64 + 0.997 0.866 -0.495
ENSG00000130052 E011 2.5505478 0.0066814231 0.67211285 0.8641091 X 68717200 68717211 12 + 0.568 0.519 -0.229
ENSG00000130052 E012 72.0931782 0.0005513124 0.01827589 0.1194199 X 68717212 68718629 1418 + 1.888 1.822 -0.221
ENSG00000130052 E013 14.8978471 0.0010175253 0.07787333 0.2854826 X 68719225 68719398 174 + 1.246 1.127 -0.424
ENSG00000130052 E014 15.6549453 0.0009165636 0.20003360 0.4819357 X 68720264 68720423 160 + 1.251 1.171 -0.283
ENSG00000130052 E015 23.8323055 0.0100298726 0.66159111 0.8587567 X 68720924 68721122 199 + 1.400 1.381 -0.064
ENSG00000130052 E016 27.7753365 0.0112181245 0.98645593 0.9993426 X 68721536 68721746 211 + 1.451 1.462 0.038
ENSG00000130052 E017 16.1987941 0.0127640735 0.90314128 0.9688647 X 68722047 68722161 115 + 1.231 1.234 0.012
ENSG00000130052 E018 21.6008055 0.0009613965 0.16440831 0.4336886 X 68722422 68722646 225 + 1.382 1.308 -0.257
ENSG00000130052 E019 25.0596928 0.0008246656 0.10500307 0.3388927 X 68723626 68723843 218 + 1.362 1.470 0.373
ENSG00000130052 E020 28.7527353 0.0005269547 0.98357956 0.9986903 X 68723945 68724121 177 + 1.463 1.479 0.053
ENSG00000130052 E021 175.8501115 0.0042481368 0.00221484 0.0275878 X 68724305 68725858 1554 + 2.202 2.293 0.305

Help

Please Click HERE to learn more details about the results from DEXseq.