ENSG00000130150

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000380492 ENSG00000130150 No_inf pgKDN_inf MOSPD2 protein_coding protein_coding 12.08603 16.75957 10.49981 1.075165 0.4861979 -0.6741094 5.566645 4.980957 6.817281 0.2701997 0.9070561 0.4519946 0.5032333 0.298400 0.649975 0.351575 0.04010384 0.04010384 FALSE TRUE
ENST00000461777 ENSG00000130150 No_inf pgKDN_inf MOSPD2 protein_coding retained_intron 12.08603 16.75957 10.49981 1.075165 0.4861979 -0.6741094 1.550254 3.015311 0.899664 0.5011113 0.2634381 -1.7336779 0.1149167 0.176775 0.083300 -0.093475 0.50669396 0.04010384 FALSE FALSE
MSTRG.29727.2 ENSG00000130150 No_inf pgKDN_inf MOSPD2 protein_coding   12.08603 16.75957 10.49981 1.075165 0.4861979 -0.6741094 1.690540 3.283454 0.771633 0.5891987 0.1594751 -2.0750381 0.1219750 0.194775 0.072175 -0.122600 0.34680335 0.04010384   FALSE
MSTRG.29727.8 ENSG00000130150 No_inf pgKDN_inf MOSPD2 protein_coding   12.08603 16.75957 10.49981 1.075165 0.4861979 -0.6741094 2.610762 4.123714 1.464919 0.6864505 0.8545897 -1.4868032 0.2125417 0.247500 0.143875 -0.103625 0.65160762 0.04010384 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000130150 E001 0.1176306 0.0118228724 0.377828934   X 14873421 14873434 14 + 0.112 0.000 -9.789
ENSG00000130150 E002 0.7518973 0.0133143803 0.200070988 0.48198270 X 14873435 14873454 20 + 0.112 0.305 1.790
ENSG00000130150 E003 1.6010372 0.0092339874 0.825716176 0.93688206 X 14873455 14873490 36 + 0.393 0.420 0.146
ENSG00000130150 E004 1.7293721 0.0080438818 0.661258293 0.85865667 X 14873491 14873528 38 + 0.393 0.452 0.316
ENSG00000130150 E005 1.3484664 0.0099957577 0.793700850 0.92135878 X 14873529 14873537 9 + 0.393 0.347 -0.269
ENSG00000130150 E006 2.1992430 0.1363296273 0.665592067 0.86092627 X 14873689 14873758 70 + 0.562 0.452 -0.530
ENSG00000130150 E007 0.0000000       X 14873759 14874454 696 +      
ENSG00000130150 E008 0.0000000       X 14885291 14885457 167 +      
ENSG00000130150 E009 5.2620529 0.0027444097 0.202014451 0.48445742 X 14892723 14892878 156 + 0.874 0.722 -0.599
ENSG00000130150 E010 5.6314797 0.0027275108 0.002289880 0.02826060 X 14892879 14893382 504 + 0.562 0.921 1.468
ENSG00000130150 E011 4.5157035 0.0039297519 0.001463485 0.02006905 X 14893896 14894263 368 + 0.442 0.852 1.790
ENSG00000130150 E012 2.1291547 0.0124757690 0.039110843 0.19148549 X 14895225 14895307 83 + 0.275 0.585 1.690
ENSG00000130150 E013 7.3061164 0.0926655048 0.464961339 0.73427044 X 14895308 14895394 87 + 0.838 0.951 0.431
ENSG00000130150 E014 9.1000662 0.0023946076 0.002727884 0.03209548 X 14897084 14897238 155 + 0.799 1.086 1.080
ENSG00000130150 E015 5.3669815 0.0049496753 0.013109949 0.09588717 X 14900575 14900635 61 + 0.596 0.887 1.191
ENSG00000130150 E016 3.9714088 0.0035177161 0.235309809 0.52455978 X 14902966 14903004 39 + 0.596 0.739 0.606
ENSG00000130150 E017 4.9464874 0.0530434000 0.661389049 0.85872362 X 14908860 14908921 62 + 0.734 0.784 0.204
ENSG00000130150 E018 6.5080622 0.0615001523 0.574020470 0.80911638 X 14908922 14908984 63 + 0.922 0.826 -0.369
ENSG00000130150 E019 12.6762135 0.0010830525 0.793881332 0.92138041 X 14911237 14911413 177 + 1.145 1.114 -0.109
ENSG00000130150 E020 9.0474460 0.0041286789 0.140542567 0.39889826 X 14912249 14912361 113 + 0.907 1.040 0.498
ENSG00000130150 E021 7.0658199 0.0110364412 0.147240767 0.40846022 X 14914503 14914599 97 + 0.799 0.951 0.584
ENSG00000130150 E022 0.3635961 0.0168634049 0.392010138   X 14915434 14915665 232 + 0.201 0.080 -1.532
ENSG00000130150 E023 7.9960485 0.0019136820 0.791116885 0.91993774 X 14915668 14915764 97 + 0.966 0.931 -0.130
ENSG00000130150 E024 10.7357555 0.0019263478 0.647018269 0.85063093 X 14916197 14916326 130 + 1.042 1.071 0.109
ENSG00000130150 E025 10.7658763 0.0014652440 0.177557759 0.45220759 X 14918680 14918782 103 + 0.993 1.100 0.394
ENSG00000130150 E026 8.1443085 0.0020707790 0.732415146 0.89363131 X 14919672 14919805 134 + 0.937 0.961 0.090
ENSG00000130150 E027 11.7136293 0.0066768592 0.009762899 0.07909742 X 14919806 14920030 225 + 1.220 0.989 -0.834
ENSG00000130150 E028 74.4311069 0.0057570605 0.001114421 0.01630193 X 14920031 14921379 1349 + 1.942 1.811 -0.441
ENSG00000130150 E029 41.5778675 0.0005111657 0.355103263 0.64483147 X 14921380 14922327 948 + 1.649 1.599 -0.171

Help

Please Click HERE to learn more details about the results from DEXseq.