ENSG00000130175

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000586486 ENSG00000130175 No_inf pgKDN_inf PRKCSH protein_coding nonsense_mediated_decay 241.6622 270.61 223.0983 3.316534 4.28452 -0.2785244 19.81182 21.797424 16.404317 2.831112 1.337457 -0.4098647 0.08188333 0.080325 0.073625 -0.006700 0.93267638 0.04094482 TRUE TRUE
ENST00000591462 ENSG00000130175 No_inf pgKDN_inf PRKCSH protein_coding protein_coding 241.6622 270.61 223.0983 3.316534 4.28452 -0.2785244 12.02611 9.374008 18.046115 3.803627 6.100446 0.9442113 0.05089167 0.035075 0.079400 0.044325 0.86438923 0.04094482 FALSE TRUE
ENST00000592741 ENSG00000130175 No_inf pgKDN_inf PRKCSH protein_coding protein_coding 241.6622 270.61 223.0983 3.316534 4.28452 -0.2785244 13.12255 17.348059 8.986296 2.998618 3.750910 -0.9482026 0.05348333 0.064400 0.039875 -0.024525 0.77730156 0.04094482 FALSE TRUE
ENST00000676823 ENSG00000130175 No_inf pgKDN_inf PRKCSH protein_coding protein_coding 241.6622 270.61 223.0983 3.316534 4.28452 -0.2785244 14.26750 13.600163 22.814692 4.819085 3.688888 0.7459111 0.06006667 0.050325 0.101950 0.051625 0.65841103 0.04094482 FALSE FALSE
ENST00000677123 ENSG00000130175 No_inf pgKDN_inf PRKCSH protein_coding protein_coding 241.6622 270.61 223.0983 3.316534 4.28452 -0.2785244 38.10089 50.165800 9.181847 9.313358 9.181847 -2.4485650 0.15365833 0.184300 0.041025 -0.143275 0.04094482 0.04094482 FALSE TRUE
MSTRG.14545.5 ENSG00000130175 No_inf pgKDN_inf PRKCSH protein_coding   241.6622 270.61 223.0983 3.316534 4.28452 -0.2785244 99.28414 120.728036 92.058242 6.247112 5.249129 -0.3911047 0.40915833 0.446900 0.413050 -0.033850 0.83437237 0.04094482 FALSE TRUE
MSTRG.14545.6 ENSG00000130175 No_inf pgKDN_inf PRKCSH protein_coding   241.6622 270.61 223.0983 3.316534 4.28452 -0.2785244 14.67952 0.000000 30.384830 0.000000 13.494843 11.5696102 0.06630833 0.000000 0.138325 0.138325 0.05775796 0.04094482 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000130175 E001 0.0000000       19 11435284 11435400 117 +      
ENSG00000130175 E002 0.0000000       19 11435401 11435442 42 +      
ENSG00000130175 E003 0.0000000       19 11435443 11435443 1 +      
ENSG00000130175 E004 0.0000000       19 11435444 11435618 175 +      
ENSG00000130175 E005 0.0000000       19 11435619 11435623 5 +      
ENSG00000130175 E006 0.0000000       19 11435624 11435626 3 +      
ENSG00000130175 E007 0.0000000       19 11435627 11435629 3 +      
ENSG00000130175 E008 0.0000000       19 11435630 11435631 2 +      
ENSG00000130175 E009 0.0000000       19 11435632 11435634 3 +      
ENSG00000130175 E010 0.0000000       19 11435635 11435644 10 +      
ENSG00000130175 E011 0.0000000       19 11435645 11435672 28 +      
ENSG00000130175 E012 0.0000000       19 11435673 11435706 34 +      
ENSG00000130175 E013 0.0000000       19 11435707 11435710 4 +      
ENSG00000130175 E014 0.0000000       19 11435740 11435744 5 +      
ENSG00000130175 E015 0.0000000       19 11435745 11435808 64 +      
ENSG00000130175 E016 0.0000000       19 11435809 11436040 232 +      
ENSG00000130175 E017 21.2005636 4.813395e-03 0.0677762994 0.262717777 19 11436041 11436085 45 + 1.409 1.283 -0.439
ENSG00000130175 E018 42.3256424 4.626907e-04 0.0285112934 0.158097840 19 11436086 11436117 32 + 1.686 1.585 -0.346
ENSG00000130175 E019 130.5828551 2.382968e-03 0.0615826572 0.249373004 19 11436118 11436196 79 + 2.147 2.085 -0.208
ENSG00000130175 E020 0.1176306 1.179760e-02 0.3897768582   19 11436197 11436388 192 + 0.109 0.000 -10.771
ENSG00000130175 E021 206.3911025 1.522607e-03 0.5071820287 0.765670815 19 11436389 11436505 117 + 2.319 2.302 -0.059
ENSG00000130175 E022 0.2541163 1.604196e-02 0.3706302376   19 11436534 11436723 190 + 0.000 0.152 10.755
ENSG00000130175 E023 172.5377178 1.351325e-04 0.1569138208 0.423264773 19 11437876 11437971 96 + 2.251 2.218 -0.110
ENSG00000130175 E024 129.4492379 2.787054e-04 0.1004174007 0.330898970 19 11438067 11438124 58 + 2.133 2.089 -0.150
ENSG00000130175 E025 0.7258129 3.117596e-02 0.2381441245 0.527070502 19 11441069 11441239 171 + 0.332 0.152 -1.455
ENSG00000130175 E026 190.1412651 1.226541e-04 0.8476796854 0.946009687 19 11441240 11441357 118 + 2.276 2.271 -0.015
ENSG00000130175 E027 88.3961772 2.515102e-03 0.6225157064 0.837359390 19 11442386 11442406 21 + 1.932 1.950 0.061
ENSG00000130175 E028 213.8804566 5.119419e-04 0.7053212093 0.880247920 19 11442407 11442515 109 + 2.319 2.327 0.028
ENSG00000130175 E029 182.9991674 7.865618e-04 0.2313183674 0.519851862 19 11445389 11445473 85 + 2.239 2.269 0.100
ENSG00000130175 E030 3.6382778 4.511086e-03 0.0045724883 0.046513124 19 11445474 11445846 373 + 0.386 0.779 1.808
ENSG00000130175 E031 118.1682666 2.524694e-04 0.2402230529 0.529429149 19 11446272 11446315 44 + 2.048 2.081 0.112
ENSG00000130175 E032 118.6216632 1.162730e-03 0.1042563189 0.337444757 19 11446316 11446350 35 + 2.039 2.089 0.170
ENSG00000130175 E033 0.7522145 3.778218e-02 0.1963019842 0.476957227 19 11447065 11447073 9 + 0.109 0.311 1.866
ENSG00000130175 E034 103.9769664 3.867288e-04 0.9448544984 0.984798063 19 11447074 11447120 47 + 2.012 2.014 0.007
ENSG00000130175 E035 94.8588034 1.620558e-04 0.9889671968 1.000000000 19 11447121 11447160 40 + 1.974 1.973 -0.002
ENSG00000130175 E036 98.8606326 8.038793e-04 0.6708386219 0.863281960 19 11447439 11447564 126 + 1.983 1.997 0.046
ENSG00000130175 E037 75.9224511 5.867792e-03 0.2827245047 0.576361827 19 11447565 11447597 33 + 1.846 1.899 0.179
ENSG00000130175 E038 44.9386784 6.881368e-03 0.6687820943 0.862137135 19 11447598 11447618 21 + 1.668 1.644 -0.082
ENSG00000130175 E039 1.3711205 9.345838e-03 0.3102167218 0.603473311 19 11447619 11447692 74 + 0.269 0.427 0.960
ENSG00000130175 E040 69.1524886 4.918579e-03 0.2324924618 0.521165770 19 11447693 11447695 3 + 1.803 1.860 0.194
ENSG00000130175 E041 89.8770843 3.871311e-04 0.1034543399 0.336203404 19 11447696 11447722 27 + 1.917 1.971 0.181
ENSG00000130175 E042 147.1822570 1.298566e-04 0.3340950186 0.625988561 19 11447723 11447789 67 + 2.177 2.153 -0.082
ENSG00000130175 E043 2.5150086 1.585600e-01 0.0430772727 0.202403171 19 11447790 11447933 144 + 0.270 0.658 2.047
ENSG00000130175 E044 1.3783623 9.805538e-03 0.0933418692 0.317601437 19 11447934 11447997 64 + 0.197 0.460 1.715
ENSG00000130175 E045 1.9616419 6.783769e-02 0.5979304980 0.823660600 19 11447998 11448221 224 + 0.518 0.427 -0.456
ENSG00000130175 E046 133.5868954 3.773909e-03 0.3145418784 0.607567535 19 11448222 11448291 70 + 2.143 2.105 -0.125
ENSG00000130175 E047 5.7682182 2.828988e-03 0.0003844495 0.007074342 19 11448292 11448536 245 + 0.518 0.952 1.793
ENSG00000130175 E048 1.3608929 2.341291e-02 0.7005587500 0.877981541 19 11448537 11448539 3 + 0.332 0.392 0.352
ENSG00000130175 E049 198.5421022 1.112304e-04 0.8781559084 0.958605058 19 11448540 11448629 90 + 2.294 2.290 -0.011
ENSG00000130175 E050 190.4204568 3.157464e-04 0.9963078546 1.000000000 19 11448914 11448988 75 + 2.274 2.274 0.000
ENSG00000130175 E051 0.9882650 1.587633e-02 0.7903162255 0.919664104 19 11448989 11449075 87 + 0.269 0.311 0.282
ENSG00000130175 E052 199.3282515 1.088493e-04 0.7200921460 0.887266565 19 11449076 11449175 100 + 2.298 2.290 -0.026
ENSG00000130175 E053 268.4654365 1.506143e-04 0.3905347923 0.676120780 19 11449266 11449428 163 + 2.413 2.429 0.053
ENSG00000130175 E054 77.1265621 1.990295e-04 0.8684867507 0.954837109 19 11449429 11449778 350 + 1.881 1.887 0.019
ENSG00000130175 E055 24.1127357 7.848238e-04 0.6372292477 0.845160627 19 11449779 11449882 104 + 1.409 1.380 -0.100
ENSG00000130175 E056 18.7444558 8.353619e-04 0.8552631418 0.949109770 19 11449883 11449987 105 + 1.280 1.292 0.043
ENSG00000130175 E057 41.5776077 1.480689e-03 0.0483779393 0.216532430 19 11449988 11450428 441 + 1.676 1.580 -0.328
ENSG00000130175 E058 48.4317900 2.949021e-04 0.7780001645 0.914866436 19 11450429 11450585 157 + 1.679 1.691 0.042
ENSG00000130175 E059 34.1158259 4.153744e-04 0.8895746465 0.963259416 19 11450586 11450645 60 + 1.542 1.534 -0.025
ENSG00000130175 E060 278.9985122 8.336508e-05 0.4880965890 0.751520210 19 11450646 11450968 323 + 2.432 2.444 0.042

Help

Please Click HERE to learn more details about the results from DEXseq.