ENSG00000130202

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000252483 ENSG00000130202 No_inf pgKDN_inf NECTIN2 protein_coding protein_coding 106.7085 76.58205 115.2205 3.248265 1.437365 0.5892556 32.944996 23.126160 33.657362 2.842485 2.478220 0.5412012 0.30883333 0.305650 0.292825 -0.012825 0.99114512 0.01464719 FALSE TRUE
ENST00000252485 ENSG00000130202 No_inf pgKDN_inf NECTIN2 protein_coding protein_coding 106.7085 76.58205 115.2205 3.248265 1.437365 0.5892556 39.257179 21.871917 43.591505 1.832157 1.750287 0.9946388 0.35731667 0.285025 0.378450 0.093425 0.30358749 0.01464719 FALSE TRUE
ENST00000585601 ENSG00000130202 No_inf pgKDN_inf NECTIN2 protein_coding protein_coding 106.7085 76.58205 115.2205 3.248265 1.437365 0.5892556 11.303283 9.687567 17.177918 3.555598 4.315875 0.8257000 0.11017500 0.126250 0.150225 0.023975 0.86423132 0.01464719   FALSE
ENST00000591581 ENSG00000130202 No_inf pgKDN_inf NECTIN2 protein_coding protein_coding 106.7085 76.58205 115.2205 3.248265 1.437365 0.5892556 12.148461 15.055904 6.160403 2.688890 6.160403 -1.2878506 0.12339167 0.198050 0.053350 -0.144700 0.01464719 0.01464719 FALSE FALSE
MSTRG.15299.2 ENSG00000130202 No_inf pgKDN_inf NECTIN2 protein_coding   106.7085 76.58205 115.2205 3.248265 1.437365 0.5892556 6.963778 0.000000 11.070870 0.000000 6.404468 10.1138555 0.05690833 0.000000 0.095150 0.095150 0.80123931 0.01464719 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000130202 E001 0.5002381 0.0262138575 1.678067e-01 4.386839e-01 19 44846175 44846284 110 + 0.080 0.277 2.149
ENSG00000130202 E002 1.0983402 0.0526309060 8.025251e-01 9.264424e-01 19 44846285 44846296 12 + 0.302 0.341 0.243
ENSG00000130202 E003 101.0620187 0.0004056747 2.152412e-03 2.698851e-02 19 44846297 44846613 317 + 2.041 1.946 -0.320
ENSG00000130202 E004 138.5556701 0.0027579672 1.131400e-03 1.647207e-02 19 44865271 44865660 390 + 2.181 2.075 -0.353
ENSG00000130202 E005 147.3278514 0.0001141641 2.394634e-01 5.285498e-01 19 44871853 44872149 297 + 2.178 2.148 -0.101
ENSG00000130202 E006 48.3812550 0.0047119920 8.637310e-01 9.528704e-01 19 44873916 44873941 26 + 1.693 1.682 -0.039
ENSG00000130202 E007 80.2043336 0.0017628657 9.917492e-02 3.288595e-01 19 44873942 44874033 92 + 1.879 1.937 0.194
ENSG00000130202 E008 57.4752166 0.0030641877 4.827518e-02 2.162429e-01 19 44874330 44874378 49 + 1.724 1.809 0.288
ENSG00000130202 E009 49.9188547 0.0003027615 4.690872e-01 7.370862e-01 19 44874379 44874462 84 + 1.689 1.718 0.096
ENSG00000130202 E010 20.9890262 0.0007211817 3.875850e-01 6.733455e-01 19 44874463 44874478 16 + 1.361 1.302 -0.204
ENSG00000130202 E011 1.9902485 0.1106003360 5.056596e-02 2.222315e-01 19 44874479 44874689 211 + 0.303 0.631 1.701
ENSG00000130202 E012 35.2611256 0.0003924476 9.401526e-01 9.830357e-01 19 44878223 44878372 150 + 1.557 1.551 -0.020
ENSG00000130202 E013 59.0007499 0.0008110005 4.383029e-01 7.145060e-01 19 44878373 44878552 180 + 1.787 1.753 -0.112
ENSG00000130202 E014 99.1958147 0.0001717540 7.576922e-01 9.048218e-01 19 44878553 44878941 389 + 2.000 1.989 -0.038
ENSG00000130202 E015 0.0000000       19 44882211 44882337 127 +      
ENSG00000130202 E016 4.4967438 0.0040283190 9.690437e-01 9.936412e-01 19 44882338 44882364 27 + 0.735 0.738 0.012
ENSG00000130202 E017 12.1865723 0.0162494438 5.206742e-01 7.748515e-01 19 44885937 44886000 64 + 1.089 1.149 0.217
ENSG00000130202 E018 19.8385616 0.0096357491 6.392284e-01 8.465336e-01 19 44886133 44886219 87 + 1.299 1.333 0.119
ENSG00000130202 E019 148.4317536 0.0001617593 1.007375e-06 4.691861e-05 19 44888110 44889223 1114 + 2.118 2.231 0.377

Help

Please Click HERE to learn more details about the results from DEXseq.