ENSG00000130227

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000252512 ENSG00000130227 No_inf pgKDN_inf XPO7 protein_coding protein_coding 31.8223 31.69954 33.10663 1.158984 0.3347928 0.06263895 23.0873638 12.668701 32.491376 2.5516870 0.4508824 1.358094 0.72519167 0.404500 0.981375 0.576875 1.877742e-12 1.877742e-12 FALSE TRUE
ENST00000433566 ENSG00000130227 No_inf pgKDN_inf XPO7 protein_coding protein_coding 31.8223 31.69954 33.10663 1.158984 0.3347928 0.06263895 2.0874368 6.262311 0.000000 4.0262643 0.0000000 -9.292853 0.06640000 0.199200 0.000000 -0.199200 5.058467e-01 1.877742e-12 FALSE TRUE
ENST00000517551 ENSG00000130227 No_inf pgKDN_inf XPO7 protein_coding protein_coding 31.8223 31.69954 33.10663 1.158984 0.3347928 0.06263895 0.6049618 1.814885 0.000000 1.0561327 0.0000000 -7.511662 0.01819167 0.054575 0.000000 -0.054575 4.731956e-01 1.877742e-12 FALSE FALSE
MSTRG.27357.2 ENSG00000130227 No_inf pgKDN_inf XPO7 protein_coding   31.8223 31.69954 33.10663 1.158984 0.3347928 0.06263895 2.5303641 3.228046 0.000000 2.0326124 0.0000000 -8.338980 0.07941667 0.099750 0.000000 -0.099750 4.886614e-01 1.877742e-12 FALSE TRUE
MSTRG.27357.8 ENSG00000130227 No_inf pgKDN_inf XPO7 protein_coding   31.8223 31.69954 33.10663 1.158984 0.3347928 0.06263895 3.1108738 7.263044 0.156974 0.9864436 0.1569740 -5.444864 0.09822500 0.227550 0.004600 -0.222950 1.322057e-07 1.877742e-12 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000130227 E001 1.8105897 0.0092386810 2.592431e-01 5.518202e-01 8 21919662 21919756 95 + 0.525 0.357 -0.883
ENSG00000130227 E002 1.6935857 0.0085260771 3.617277e-01 6.511052e-01 8 21919757 21919759 3 + 0.494 0.357 -0.731
ENSG00000130227 E003 4.7316706 0.0520555070 3.037625e-01 5.971834e-01 8 21919760 21919788 29 + 0.822 0.683 -0.561
ENSG00000130227 E004 0.0000000       8 21921414 21921455 42 +      
ENSG00000130227 E005 0.0000000       8 21921456 21921626 171 +      
ENSG00000130227 E006 0.0000000       8 21964149 21964325 177 +      
ENSG00000130227 E007 0.0000000       8 21966238 21966313 76 +      
ENSG00000130227 E008 15.9114386 0.0056795495 7.816770e-02 2.861190e-01 8 21966857 21967003 147 + 1.292 1.154 -0.486
ENSG00000130227 E009 13.7310911 0.0017628627 8.744833e-02 3.065601e-01 8 21969483 21969576 94 + 1.230 1.096 -0.479
ENSG00000130227 E010 0.4998298 0.0324003826 2.860231e-01   8 21969577 21969896 320 + 0.092 0.247 1.702
ENSG00000130227 E011 18.0912195 0.0007199972 1.743414e-02 1.157617e-01 8 21970144 21970310 167 + 1.355 1.191 -0.574
ENSG00000130227 E012 11.9847381 0.0032541857 7.869821e-03 6.838262e-02 8 21971876 21971941 66 + 1.212 0.985 -0.818
ENSG00000130227 E013 0.3805619 0.5385741220 2.660710e-01   8 21971942 21971968 27 + 0.000 0.247 10.710
ENSG00000130227 E014 16.2479412 0.0029289100 6.211393e-03 5.787928e-02 8 21974670 21974774 105 + 1.327 1.122 -0.725
ENSG00000130227 E015 18.5456089 0.0007354611 4.766715e-03 4.787487e-02 8 21976356 21976521 166 + 1.377 1.184 -0.676
ENSG00000130227 E016 12.0753856 0.0459326472 6.665000e-01 8.613391e-01 8 21977770 21977843 74 + 1.136 1.096 -0.146
ENSG00000130227 E017 15.1234323 0.0147574191 4.035248e-01 6.864715e-01 8 21980084 21980203 120 + 1.242 1.169 -0.258
ENSG00000130227 E018 21.2513615 0.0007086213 6.012194e-01 8.255344e-01 8 21981731 21981877 147 + 1.364 1.330 -0.116
ENSG00000130227 E019 24.7357062 0.0026084166 2.086120e-01 4.926841e-01 8 21982640 21982812 173 + 1.448 1.370 -0.269
ENSG00000130227 E020 26.8090995 0.0005898837 1.990412e-01 4.805537e-01 8 21984646 21984839 194 + 1.479 1.406 -0.252
ENSG00000130227 E021 21.5903366 0.0011627718 3.805942e-01 6.670661e-01 8 21985586 21985691 106 + 1.381 1.325 -0.194
ENSG00000130227 E022 26.2952714 0.0146673506 9.404640e-01 9.830606e-01 8 21987141 21987276 136 + 1.433 1.439 0.023
ENSG00000130227 E023 20.3738918 0.0008921981 5.292037e-01 7.805845e-01 8 21987784 21987857 74 + 1.350 1.309 -0.143
ENSG00000130227 E024 1.6216826 0.0084710893 3.466033e-02 1.779166e-01 8 21988348 21989002 655 + 0.232 0.550 1.854
ENSG00000130227 E025 23.3515189 0.0010462337 6.084981e-02 2.475952e-01 8 21989003 21989083 81 + 1.440 1.325 -0.399
ENSG00000130227 E026 16.6395361 0.0012979246 4.708756e-02 2.131627e-01 8 21990344 21990407 64 + 1.312 1.169 -0.503
ENSG00000130227 E027 0.3813786 0.0276679224 8.998513e-02   8 21990408 21990611 204 + 0.000 0.247 11.695
ENSG00000130227 E028 23.0354757 0.0019723174 1.685574e-03 2.236952e-02 8 21990811 21990919 109 + 1.469 1.269 -0.693
ENSG00000130227 E029 1.1335318 0.0135876339 1.040139e-02 8.239442e-02 8 21991726 21991867 142 + 0.092 0.483 3.117
ENSG00000130227 E030 22.7884598 0.0007677338 4.845713e-01 7.486971e-01 8 21991868 21991974 107 + 1.355 1.397 0.148
ENSG00000130227 E031 24.7254726 0.0005684134 6.607819e-01 8.584514e-01 8 21994363 21994451 89 + 1.398 1.423 0.088
ENSG00000130227 E032 28.8097176 0.0060571838 4.682542e-01 7.364854e-01 8 21995492 21995599 108 + 1.496 1.451 -0.153
ENSG00000130227 E033 27.3869700 0.0060235624 8.541480e-01 9.485068e-01 8 21998755 21998837 83 + 1.458 1.447 -0.038
ENSG00000130227 E034 50.7740780 0.0016878272 7.818144e-01 9.160998e-01 8 21999091 21999305 215 + 1.708 1.720 0.040
ENSG00000130227 E035 42.5960910 0.0003450466 3.101579e-01 6.034652e-01 8 21999536 21999674 139 + 1.662 1.616 -0.157
ENSG00000130227 E036 43.1187299 0.0003462819 5.683677e-01 8.058874e-01 8 22002112 22002272 161 + 1.657 1.631 -0.088
ENSG00000130227 E037 0.3724075 0.0166553158 5.345659e-01   8 22002985 22003218 234 + 0.092 0.179 1.117
ENSG00000130227 E038 25.9916599 0.0032357613 4.179530e-01 6.976906e-01 8 22003219 22003317 99 + 1.406 1.455 0.171
ENSG00000130227 E039 30.5854864 0.0004812243 6.430237e-02 2.553629e-01 8 22003903 22004030 128 + 1.448 1.546 0.337
ENSG00000130227 E040 339.4416229 0.0000768306 1.033712e-12 1.347039e-10 8 22004995 22006585 1591 + 2.481 2.578 0.321

Help

Please Click HERE to learn more details about the results from DEXseq.