ENSG00000130244

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000252530 ENSG00000130244 No_inf pgKDN_inf FAM98C protein_coding protein_coding 8.221814 12.05846 5.809409 0.6692756 0.2883356 -1.052296 3.2085921 2.6868941 3.7756054 1.1676260 0.25830883 0.4892251 0.45916667 0.237375 0.650125 0.412750 0.2321276431 0.0001006759 FALSE TRUE
ENST00000586372 ENSG00000130244 No_inf pgKDN_inf FAM98C protein_coding retained_intron 8.221814 12.05846 5.809409 0.6692756 0.2883356 -1.052296 1.4086994 2.3729065 0.8431090 0.2805010 0.05737509 -1.4819204 0.16649167 0.200925 0.146775 -0.054150 0.8487804074 0.0001006759 FALSE TRUE
ENST00000589027 ENSG00000130244 No_inf pgKDN_inf FAM98C protein_coding retained_intron 8.221814 12.05846 5.809409 0.6692756 0.2883356 -1.052296 0.2715888 0.8147664 0.0000000 0.8147664 0.00000000 -6.3659137 0.01935000 0.058050 0.000000 -0.058050 0.9576654860 0.0001006759   FALSE
ENST00000589408 ENSG00000130244 No_inf pgKDN_inf FAM98C protein_coding protein_coding 8.221814 12.05846 5.809409 0.6692756 0.2883356 -1.052296 1.3873036 3.8003243 0.0000000 0.6948124 0.00000000 -8.5737700 0.12262500 0.316125 0.000000 -0.316125 0.0001006759 0.0001006759 FALSE FALSE
MSTRG.15116.5 ENSG00000130244 No_inf pgKDN_inf FAM98C protein_coding   8.221814 12.05846 5.809409 0.6692756 0.2883356 -1.052296 0.4809340 0.0000000 0.6880988 0.0000000 0.39900629 6.1253592 0.07459167 0.000000 0.119200 0.119200 0.3229523855 0.0001006759 FALSE TRUE
MSTRG.15116.8 ENSG00000130244 No_inf pgKDN_inf FAM98C protein_coding   8.221814 12.05846 5.809409 0.6692756 0.2883356 -1.052296 0.5085909 1.3542768 0.1714960 0.8346602 0.17149601 -2.9101267 0.04567500 0.103675 0.033350 -0.070325 0.8424189974 0.0001006759 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000130244 E001 0.0000000       19 38403093 38403134 42 +      
ENSG00000130244 E002 0.1271363 0.012419006 1.000000000   19 38403135 38403153 19 + 0.000 0.072 9.430
ENSG00000130244 E003 0.2447669 0.016579606 0.620559530   19 38403154 38403168 15 + 0.124 0.072 -0.870
ENSG00000130244 E004 1.1060843 0.015035882 0.546294757 0.79210316 19 38403169 38403186 18 + 0.366 0.280 -0.548
ENSG00000130244 E005 1.8572263 0.014086431 0.917226590 0.97400470 19 38403187 38403218 32 + 0.424 0.449 0.130
ENSG00000130244 E006 0.6353043 0.015073867 0.096803823 0.32401058 19 38403219 38403244 26 + 0.000 0.280 11.753
ENSG00000130244 E007 2.1493948 0.006606759 0.004381422 0.04519901 19 38403245 38403337 93 + 0.124 0.591 3.130
ENSG00000130244 E008 7.3473173 0.002051794 0.197218837 0.47846152 19 38403338 38403486 149 + 0.799 0.944 0.557
ENSG00000130244 E009 0.1268540 0.012578879 1.000000000   19 38403487 38403559 73 + 0.000 0.072 9.431
ENSG00000130244 E010 6.6701561 0.002472609 0.512637189 0.76962121 19 38403560 38403664 105 + 0.900 0.844 -0.218
ENSG00000130244 E011 4.4167309 0.005244214 0.120960331 0.36801909 19 38403665 38403694 30 + 0.821 0.647 -0.709
ENSG00000130244 E012 0.2530140 0.265611436 0.613208604   19 38404713 38404806 94 + 0.000 0.134 10.430
ENSG00000130244 E013 3.2204256 0.006712121 0.989338500 1.00000000 19 38404908 38404922 15 + 0.600 0.610 0.048
ENSG00000130244 E014 9.4788700 0.001814557 0.122810670 0.37092853 19 38404923 38405113 191 + 1.076 0.953 -0.455
ENSG00000130244 E015 0.8710110 0.013663809 0.729499277 0.89215825 19 38405254 38405343 90 + 0.221 0.280 0.452
ENSG00000130244 E016 4.9209623 0.003544585 0.174375913 0.44808089 19 38405344 38405421 78 + 0.842 0.698 -0.580
ENSG00000130244 E017 6.2666165 0.003252973 0.063493123 0.25354939 19 38405519 38405635 117 + 0.951 0.770 -0.700
ENSG00000130244 E018 8.8252556 0.008124499 0.236263490 0.52542615 19 38405636 38406743 1108 + 0.882 1.010 0.481
ENSG00000130244 E019 2.2709891 0.137905747 0.061072970 0.24820052 19 38406744 38406909 166 + 0.221 0.591 2.130
ENSG00000130244 E020 8.5138475 0.002004846 0.425561391 0.70459641 19 38406910 38407077 168 + 0.997 0.935 -0.232
ENSG00000130244 E021 10.5776193 0.002031643 0.181077626 0.45696428 19 38407078 38408750 1673 + 0.951 1.081 0.476
ENSG00000130244 E022 6.4360945 0.021129666 0.986601728 0.99938736 19 38408751 38409088 338 + 0.842 0.855 0.048

Help

Please Click HERE to learn more details about the results from DEXseq.