ENSG00000130254

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000252542 ENSG00000130254 No_inf pgKDN_inf SAFB2 protein_coding protein_coding 38.28588 42.63801 31.94147 2.213235 1.648868 -0.416596 14.346138 10.853450 17.0740083 2.5825326 1.7898995 0.6531641 0.39124167 0.248425 0.540300 0.291875 0.04505717 0.04505717 FALSE TRUE
ENST00000587802 ENSG00000130254 No_inf pgKDN_inf SAFB2 protein_coding protein_coding_CDS_not_defined 38.28588 42.63801 31.94147 2.213235 1.648868 -0.416596 2.639042 3.133558 0.7655517 0.6542042 0.5195536 -2.0191034 0.06664167 0.072400 0.023200 -0.049200 0.38573384 0.04505717   FALSE
ENST00000590000 ENSG00000130254 No_inf pgKDN_inf SAFB2 protein_coding retained_intron 38.28588 42.63801 31.94147 2.213235 1.648868 -0.416596 2.767635 2.827818 2.5629386 0.1772813 0.9809082 -0.1413652 0.07182500 0.066725 0.077175 0.010450 0.99772410 0.04505717 FALSE FALSE
ENST00000592599 ENSG00000130254 No_inf pgKDN_inf SAFB2 protein_coding retained_intron 38.28588 42.63801 31.94147 2.213235 1.648868 -0.416596 3.107671 4.683931 2.0523335 0.6544159 0.7518337 -1.1865191 0.07804167 0.111525 0.061000 -0.050525 0.72735466 0.04505717   FALSE
MSTRG.14360.1 ENSG00000130254 No_inf pgKDN_inf SAFB2 protein_coding   38.28588 42.63801 31.94147 2.213235 1.648868 -0.416596 6.679151 11.411819 3.9428320 2.3099625 1.6090875 -1.5308339 0.17123333 0.275350 0.122275 -0.153075 0.53834697 0.04505717 FALSE TRUE
MSTRG.14360.5 ENSG00000130254 No_inf pgKDN_inf SAFB2 protein_coding   38.28588 42.63801 31.94147 2.213235 1.648868 -0.416596 2.770496 3.475127 1.7858831 0.7459605 0.1870817 -0.9565178 0.07118333 0.081850 0.055800 -0.026050 0.83089076 0.04505717 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000130254 E001 0.1186381 0.0117941092 0.4126678920   19 5586999 5587005 7 - 0.107 0.000 -10.354
ENSG00000130254 E002 0.6270271 0.0148670756 0.2796186795 0.572853979 19 5587006 5587011 6 - 0.107 0.268 1.609
ENSG00000130254 E003 7.3930632 0.0110522436 0.7858793333 0.917487334 19 5587012 5587109 98 - 0.903 0.928 0.095
ENSG00000130254 E004 34.9160494 0.0071251706 0.3524476820 0.642453470 19 5587110 5587399 290 - 1.518 1.570 0.177
ENSG00000130254 E005 8.7894318 0.0018728491 0.1582085136 0.425110501 19 5587400 5587700 301 - 0.903 1.035 0.489
ENSG00000130254 E006 14.3063590 0.0113480055 0.6951803327 0.875545449 19 5587701 5587767 67 - 1.160 1.191 0.112
ENSG00000130254 E007 20.5540131 0.0012826244 0.9558362720 0.989315549 19 5587868 5587980 113 - 1.332 1.324 -0.026
ENSG00000130254 E008 4.2696163 0.0033885145 0.0003468997 0.006546428 19 5588908 5589020 113 - 0.380 0.857 2.145
ENSG00000130254 E009 22.0181776 0.0343727670 0.9213206634 0.975460883 19 5590278 5590408 131 - 1.370 1.346 -0.084
ENSG00000130254 E010 4.0742546 0.0129085104 0.6431178958 0.848695462 19 5591296 5591747 452 - 0.667 0.722 0.231
ENSG00000130254 E011 15.9402831 0.0078808436 0.2378071307 0.526795490 19 5591748 5591793 46 - 1.277 1.179 -0.347
ENSG00000130254 E012 30.0816947 0.0031050136 0.3124657712 0.605835601 19 5592747 5592887 141 - 1.522 1.459 -0.214
ENSG00000130254 E013 2.2395534 0.0070444794 0.1733714740 0.446628634 19 5593631 5593890 260 - 0.380 0.577 0.988
ENSG00000130254 E014 53.7196318 0.0234009043 0.2633029552 0.556225043 19 5593891 5594178 288 - 1.775 1.698 -0.259
ENSG00000130254 E015 39.6393984 0.0030658581 0.8219645907 0.935407240 19 5595361 5595497 137 - 1.599 1.606 0.024
ENSG00000130254 E016 1.5933246 0.0817440308 0.8454163983 0.945082473 19 5598485 5598792 308 - 0.428 0.397 -0.168
ENSG00000130254 E017 20.8475447 0.0017798091 0.2242752600 0.511807645 19 5598793 5598831 39 - 1.380 1.297 -0.289
ENSG00000130254 E018 27.0445241 0.0005180046 0.7529201320 0.902734946 19 5598832 5598884 53 - 1.454 1.433 -0.075
ENSG00000130254 E019 24.9188361 0.0005732800 0.3245146150 0.616886459 19 5600130 5600199 70 - 1.375 1.429 0.188
ENSG00000130254 E020 12.7380549 0.0010741506 0.1740027593 0.447485448 19 5600200 5600213 14 - 1.066 1.173 0.384
ENSG00000130254 E021 12.6278781 0.0010467443 0.0919527674 0.314877123 19 5600214 5600225 12 - 1.045 1.179 0.484
ENSG00000130254 E022 15.0659022 0.0012268915 0.3540126161 0.643739597 19 5600226 5600260 35 - 1.160 1.226 0.234
ENSG00000130254 E023 27.5540627 0.0051243034 0.1759642070 0.450061817 19 5604583 5604695 113 - 1.400 1.481 0.281
ENSG00000130254 E024 24.3906591 0.0070401336 0.7844666766 0.916838543 19 5604787 5604936 150 - 1.390 1.404 0.050
ENSG00000130254 E025 17.3684489 0.0117066013 0.0744044391 0.278100133 19 5609995 5610095 101 - 1.337 1.191 -0.513
ENSG00000130254 E026 1.3602329 0.0090828769 0.6336867704 0.843362425 19 5610096 5610235 140 - 0.327 0.397 0.417
ENSG00000130254 E027 1.8850472 0.0072178518 0.0122975968 0.091876795 19 5610289 5610638 350 - 0.193 0.577 2.310
ENSG00000130254 E028 11.8231608 0.0162443284 0.9220326410 0.975784559 19 5610639 5610688 50 - 1.097 1.106 0.033
ENSG00000130254 E029 7.0028909 0.0057927885 0.0007742448 0.012314397 19 5610689 5611119 431 - 0.640 1.017 1.484
ENSG00000130254 E030 7.0737055 0.0023133576 0.0429491052 0.202098526 19 5611120 5611630 511 - 1.011 0.802 -0.791
ENSG00000130254 E031 1.2515084 0.0099577079 0.1206690679 0.367443852 19 5611631 5611875 245 - 0.193 0.433 1.609
ENSG00000130254 E032 12.1439508 0.0357737930 0.1121000644 0.351859679 19 5611876 5612519 644 - 0.999 1.179 0.653
ENSG00000130254 E033 1.6316862 0.0081467352 0.0313876894 0.167179897 19 5612520 5612539 20 - 0.193 0.525 2.069
ENSG00000130254 E034 10.8261508 0.0012737136 0.8779115362 0.958506868 19 5612540 5612567 28 - 1.077 1.060 -0.061
ENSG00000130254 E035 14.8243014 0.0009475097 0.2510718341 0.542259663 19 5613465 5613527 63 - 1.143 1.226 0.295
ENSG00000130254 E036 0.6353043 0.0148320558 0.0411639120 0.196898990 19 5616128 5616131 4 - 0.000 0.316 11.791
ENSG00000130254 E037 31.4638885 0.0004582608 0.6427511655 0.848599524 19 5616132 5616335 204 - 1.522 1.493 -0.097
ENSG00000130254 E038 17.7998687 0.0291298802 0.0255652455 0.147532201 19 5616422 5616486 65 - 1.380 1.167 -0.748
ENSG00000130254 E039 20.8906481 0.0006886835 0.0104860636 0.082828845 19 5621309 5621396 88 - 1.423 1.258 -0.577
ENSG00000130254 E040 27.5731383 0.0005125780 0.1011024959 0.332062050 19 5622530 5622791 262 - 1.503 1.408 -0.327
ENSG00000130254 E041 0.0000000       19 5623951 5624046 96 -      

Help

Please Click HERE to learn more details about the results from DEXseq.