ENSG00000130270

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000526092 ENSG00000130270 No_inf pgKDN_inf ATP8B3 protein_coding protein_coding 4.783691 8.551445 2.434128 0.9965886 0.2126211 -1.808534 0.4217981 0.000000 1.26539442 0.0000000 0.10810879 6.994800 0.1756750 0.000000 0.527025 0.527025 6.198221e-07 6.198221e-07 FALSE TRUE
ENST00000533107 ENSG00000130270 No_inf pgKDN_inf ATP8B3 protein_coding retained_intron 4.783691 8.551445 2.434128 0.9965886 0.2126211 -1.808534 1.6496974 2.908733 0.37622175 1.2132211 0.21978146 -2.917841 0.3266417 0.311725 0.179375 -0.132350 8.369115e-01 6.198221e-07 FALSE TRUE
ENST00000587160 ENSG00000130270 No_inf pgKDN_inf ATP8B3 protein_coding protein_coding 4.783691 8.551445 2.434128 0.9965886 0.2126211 -1.808534 0.7159493 1.005900 0.36342797 0.3740098 0.27247168 -1.443856 0.1563750 0.109125 0.126025 0.016900 1.000000e+00 6.198221e-07 FALSE FALSE
MSTRG.14211.6 ENSG00000130270 No_inf pgKDN_inf ATP8B3 protein_coding   4.783691 8.551445 2.434128 0.9965886 0.2126211 -1.808534 0.8794279 1.860256 0.24673075 1.1335930 0.24673075 -2.864907 0.1785500 0.266700 0.097025 -0.169675 8.970427e-01 6.198221e-07 FALSE TRUE
MSTRG.14211.8 ENSG00000130270 No_inf pgKDN_inf ATP8B3 protein_coding   4.783691 8.551445 2.434128 0.9965886 0.2126211 -1.808534 0.8564011 2.153389 0.08391022 0.8197985 0.08391022 -4.525867 0.1161583 0.232675 0.028075 -0.204600 2.585350e-01 6.198221e-07 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000130270 E001 0.0000000       19 1782075 1782076 2 -      
ENSG00000130270 E002 2.5127050 0.0067364218 0.35556431 0.64534275 19 1782077 1783027 951 - 0.363 0.524 0.840
ENSG00000130270 E003 0.7541945 0.3309162405 0.91882700 0.97439961 19 1783028 1783270 243 - 0.157 0.227 0.659
ENSG00000130270 E004 0.3809703 0.0182049904 0.64097970   19 1784819 1784946 128 - 0.000 0.150 11.572
ENSG00000130270 E005 0.3798680 0.0181050362 0.64150972   19 1785159 1785297 139 - 0.000 0.150 11.572
ENSG00000130270 E006 0.3809057 0.0166421840 0.64041394   19 1785469 1785557 89 - 0.000 0.150 11.573
ENSG00000130270 E007 0.4995438 0.0160573807 1.00000000   19 1785558 1785708 151 - 0.157 0.150 -0.078
ENSG00000130270 E008 0.1265070 0.0123997478 1.00000000   19 1787103 1787186 84 - 0.000 0.056 10.226
ENSG00000130270 E009 0.5079806 0.0522296280 0.42079043 0.69995320 19 1788897 1789120 224 - 0.000 0.190 11.887
ENSG00000130270 E010 0.3810317 0.0249380571 0.64219685   19 1789361 1789614 254 - 0.000 0.150 11.569
ENSG00000130270 E011 0.2537694 0.0166390087 1.00000000   19 1789615 1789727 113 - 0.000 0.106 11.090
ENSG00000130270 E012 0.0000000       19 1789890 1789989 100 -      
ENSG00000130270 E013 0.0000000       19 1790757 1790832 76 -      
ENSG00000130270 E014 0.0000000       19 1791750 1791861 112 -      
ENSG00000130270 E015 0.0000000       19 1791971 1792000 30 -      
ENSG00000130270 E016 0.0000000       19 1792001 1792135 135 -      
ENSG00000130270 E017 0.0000000       19 1795875 1795987 113 -      
ENSG00000130270 E018 0.0000000       19 1796077 1796265 189 -      
ENSG00000130270 E019 0.0000000       19 1796711 1796879 169 -      
ENSG00000130270 E020 0.0000000       19 1796974 1797005 32 -      
ENSG00000130270 E021 0.1271363 0.0125748278 1.00000000   19 1798761 1798763 3 - 0.000 0.056 10.226
ENSG00000130270 E022 19.8557222 0.0008168424 0.99521281 1.00000000 19 1798764 1799946 1183 - 1.233 1.250 0.059
ENSG00000130270 E023 6.3319230 0.0112820731 0.18773713 0.46592187 19 1799947 1800155 209 - 0.901 0.765 -0.533
ENSG00000130270 E024 7.7092425 0.0018202689 0.27660386 0.57010900 19 1800259 1800449 191 - 0.946 0.848 -0.373
ENSG00000130270 E025 1.4885641 0.0102626535 0.43085564 0.70861148 19 1801956 1801958 3 - 0.438 0.322 -0.663
ENSG00000130270 E026 3.4821520 0.0047062605 0.51337681 0.77021517 19 1801959 1802044 86 - 0.652 0.574 -0.341
ENSG00000130270 E027 0.0000000       19 1802045 1802062 18 -      
ENSG00000130270 E028 4.2453799 0.0707397240 0.94444746 0.98457223 19 1802487 1802645 159 - 0.652 0.660 0.037
ENSG00000130270 E029 0.0000000       19 1805190 1805279 90 -      
ENSG00000130270 E030 1.7400024 0.0203996830 0.65076071 0.85297288 19 1805374 1805456 83 - 0.438 0.376 -0.341
ENSG00000130270 E031 2.3494714 0.0059784273 0.18257125 0.45899398 19 1805888 1805958 71 - 0.607 0.423 -0.885
ENSG00000130270 E032 2.0016095 0.0103322815 0.66155776 0.85875608 19 1805959 1806096 138 - 0.363 0.445 0.453
ENSG00000130270 E033 3.2476138 0.0053042680 0.97994372 0.99770971 19 1806097 1806169 73 - 0.558 0.574 0.074
ENSG00000130270 E034 1.3897234 0.0305881614 0.23415554 0.52319765 19 1806170 1806508 339 - 0.157 0.376 1.659
ENSG00000130270 E035 2.7642466 0.0057122109 0.25293146 0.54427088 19 1806628 1806689 62 - 0.363 0.558 1.000
ENSG00000130270 E036 3.1357086 0.0065196776 0.36643858 0.65515808 19 1807168 1807266 99 - 0.438 0.590 0.730
ENSG00000130270 E037 1.9965451 0.1743960701 0.80840314 0.92926991 19 1808222 1808335 114 - 0.438 0.423 -0.078
ENSG00000130270 E038 0.5078857 0.0164629079 0.41144237 0.69311907 19 1808336 1808391 56 - 0.000 0.190 11.905
ENSG00000130270 E039 2.1315504 0.0074905268 0.56975003 0.80661744 19 1809643 1809734 92 - 0.363 0.466 0.560
ENSG00000130270 E040 2.3765711 0.0066994781 0.81367040 0.93184905 19 1810622 1810683 62 - 0.438 0.486 0.244
ENSG00000130270 E041 1.2149968 0.0108115398 0.01334957 0.09698581 19 1811489 1811600 112 - 0.558 0.190 -2.248
ENSG00000130270 E042 2.7459260 0.0053904349 0.94970588 0.98690655 19 1811601 1811666 66 - 0.502 0.524 0.103
ENSG00000130270 E043 3.5045036 0.0297418938 0.50139188 0.76140527 19 1811667 1811884 218 - 0.502 0.619 0.539
ENSG00000130270 E044 0.0000000       19 1812068 1812185 118 -      
ENSG00000130270 E045 1.5041759 0.0585311012 0.60483017 0.82775281 19 1812186 1812276 91 - 0.272 0.376 0.659

Help

Please Click HERE to learn more details about the results from DEXseq.