ENSG00000130300

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000252590 ENSG00000130300 No_inf pgKDN_inf PLVAP protein_coding protein_coding 26.52218 30.27075 28.69039 5.553253 1.148101 -0.07733052 21.587059 17.398059 26.7577 1.483975 0.9007265 0.6207378 0.8625667 0.648125 0.939575 0.29145 0.372143294 0.007421546 FALSE TRUE
ENST00000595816 ENSG00000130300 No_inf pgKDN_inf PLVAP protein_coding protein_coding 26.52218 30.27075 28.69039 5.553253 1.148101 -0.07733052 3.273334 9.820001 0.0000 5.501129 0.0000000 -9.9410477 0.0883000 0.264900 0.000000 -0.26490 0.007421546 0.007421546   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000130300 E001 0.000000       19 17351450 17351454 5 -      
ENSG00000130300 E002 2.974074 0.0051524338 0.024120935 0.14226473 19 17351455 17351483 29 - 0.432 0.740 1.398
ENSG00000130300 E003 17.460171 0.0010590315 0.006139601 0.05745848 19 17351484 17351642 159 - 1.166 1.360 0.683
ENSG00000130300 E004 116.273802 0.0033795495 0.009515960 0.07786888 19 17351643 17352368 726 - 2.029 2.109 0.267
ENSG00000130300 E005 16.041872 0.0118795101 0.387428807 0.67331267 19 17360528 17360609 82 - 1.257 1.193 -0.224
ENSG00000130300 E006 16.128841 0.0009299162 0.111548299 0.35071971 19 17360772 17360832 61 - 1.277 1.169 -0.380
ENSG00000130300 E007 26.494969 0.0006967225 0.329755729 0.62221858 19 17365286 17365415 130 - 1.458 1.410 -0.165
ENSG00000130300 E008 14.583171 0.0011214416 0.427969612 0.70647995 19 17365416 17365465 50 - 1.214 1.161 -0.187
ENSG00000130300 E009 51.523496 0.0004511533 0.732180403 0.89358748 19 17365466 17365948 483 - 1.721 1.715 -0.022
ENSG00000130300 E010 9.288498 0.0033479411 0.028350002 0.15755065 19 17365949 17365972 24 - 1.090 0.889 -0.745
ENSG00000130300 E011 8.351937 0.0018406024 0.138129364 0.39551227 19 17365973 17365998 26 - 1.025 0.889 -0.509
ENSG00000130300 E012 14.824559 0.0016561221 0.448944566 0.72288824 19 17366099 17366195 97 - 1.219 1.169 -0.178
ENSG00000130300 E013 42.892531 0.0003629015 0.146762097 0.40781634 19 17376920 17377342 423 - 1.665 1.609 -0.191

Help

Please Click HERE to learn more details about the results from DEXseq.