ENSG00000130309

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000252599 ENSG00000130309 No_inf pgKDN_inf COLGALT1 protein_coding protein_coding 91.1092 75.03433 96.96274 1.140252 2.012584 0.3698363 19.54953 11.32159 22.050125 1.269745 2.1461689 0.9610911 0.2092917 0.151025 0.227700 0.076675 0.448232974 0.002091737 FALSE TRUE
ENST00000593832 ENSG00000130309 No_inf pgKDN_inf COLGALT1 protein_coding retained_intron 91.1092 75.03433 96.96274 1.140252 2.012584 0.3698363 13.29356 18.48478 9.752878 1.198667 0.8223673 -0.9217399 0.1538833 0.245975 0.100775 -0.145200 0.002091737 0.002091737 FALSE TRUE
MSTRG.14750.8 ENSG00000130309 No_inf pgKDN_inf COLGALT1 protein_coding   91.1092 75.03433 96.96274 1.140252 2.012584 0.3698363 56.04130 42.06551 63.485121 1.722342 3.3576163 0.5936650 0.6110917 0.561225 0.654300 0.093075 0.430567387 0.002091737 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000130309 E001 7.1727390 0.0021273933 4.839042e-01 7.483123e-01 19 17555649 17555713 65 + 0.944 0.873 -0.269
ENSG00000130309 E002 10.3167427 0.0016522989 2.367924e-01 5.256921e-01 19 17555714 17555800 87 + 1.099 0.995 -0.381
ENSG00000130309 E003 16.3573419 0.0059634988 5.174239e-02 2.258010e-01 19 17555801 17555973 173 + 1.304 1.152 -0.536
ENSG00000130309 E004 0.7358776 0.0135071870 8.181108e-01 9.337997e-01 19 17556561 17556679 119 + 0.222 0.257 0.275
ENSG00000130309 E005 0.6245427 0.0469558402 1.243182e-01 3.736197e-01 19 17557418 17557444 27 + 0.087 0.317 2.276
ENSG00000130309 E006 42.5670781 0.0003670830 9.162621e-01 9.737077e-01 19 17559311 17559421 111 + 1.641 1.636 -0.015
ENSG00000130309 E007 61.0017601 0.0051753791 9.244847e-01 9.771507e-01 19 17560348 17560465 118 + 1.790 1.793 0.009
ENSG00000130309 E008 0.5074773 0.0156944628 2.857499e-02 1.583279e-01 19 17566033 17566183 151 + 0.000 0.317 12.304
ENSG00000130309 E009 62.3423413 0.0007325894 2.321489e-01 5.208252e-01 19 17567406 17567540 135 + 1.822 1.776 -0.156
ENSG00000130309 E010 76.5096205 0.0009222632 3.872854e-02 1.904089e-01 19 17568509 17568709 201 + 1.922 1.848 -0.249
ENSG00000130309 E011 14.9270001 0.0013876462 5.463641e-02 2.328350e-01 19 17568710 17568713 4 + 1.264 1.118 -0.518
ENSG00000130309 E012 1.8471560 0.0077762187 2.590983e-01 5.516426e-01 19 17571870 17571987 118 + 0.368 0.534 0.860
ENSG00000130309 E013 0.7514889 0.0139755441 5.740621e-02 2.395735e-01 19 17571988 17571991 4 + 0.087 0.370 2.597
ENSG00000130309 E014 51.5985546 0.0002808698 9.668474e-02 3.238275e-01 19 17572483 17572602 120 + 1.751 1.682 -0.233
ENSG00000130309 E015 1.4952354 0.0102164479 3.905871e-02 1.913519e-01 19 17572603 17573798 1196 + 0.222 0.534 1.860
ENSG00000130309 E016 0.1268540 0.0122978104 4.448050e-01   19 17577075 17577194 120 + 0.000 0.104 10.382
ENSG00000130309 E017 37.8990532 0.0003954231 5.108173e-01 7.682130e-01 19 17577195 17577271 77 + 1.604 1.572 -0.107
ENSG00000130309 E018 52.3718348 0.0069135368 3.770374e-01 6.641424e-01 19 17577361 17577467 107 + 1.748 1.701 -0.157
ENSG00000130309 E019 48.2272852 0.0014894614 3.207190e-01 6.136404e-01 19 17577957 17578089 133 + 1.712 1.668 -0.150
ENSG00000130309 E020 56.3691660 0.0024322915 4.478575e-04 8.016842e-03 19 17579482 17579609 128 + 1.825 1.668 -0.533
ENSG00000130309 E021 35.9668332 0.0003906523 2.234113e-14 3.640321e-12 19 17579951 17580698 748 + 1.341 1.731 1.336
ENSG00000130309 E022 127.2275877 0.0001426230 5.964018e-01 8.226053e-01 19 17580699 17580905 207 + 2.100 2.115 0.048
ENSG00000130309 E023 922.0500766 0.0001707519 1.792248e-02 1.179969e-01 19 17581177 17583162 1986 + 2.956 2.973 0.057

Help

Please Click HERE to learn more details about the results from DEXseq.