ENSG00000130313

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000252603 ENSG00000130313 No_inf pgKDN_inf PGLS protein_coding protein_coding 56.85294 66.34226 51.76643 1.154612 1.462175 -0.3578501 50.934524 57.81625 49.111175 1.2321325 1.5978762 -0.2353795 0.89848333 0.871600 0.948425 0.076825 0.005562288 0.005562288 FALSE  
ENST00000598811 ENSG00000130313 No_inf pgKDN_inf PGLS protein_coding retained_intron 56.85294 66.34226 51.76643 1.154612 1.462175 -0.3578501 3.358133 6.06403 1.818446 0.7602745 0.2252455 -1.7320363 0.05610833 0.091475 0.035375 -0.056100 0.185478335 0.005562288    
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000130313 E001 0.0000000       19 17511636 17511643 8 +      
ENSG00000130313 E002 0.0000000       19 17511644 17511648 5 +      
ENSG00000130313 E003 0.0000000       19 17511649 17511669 21 +      
ENSG00000130313 E004 0.0000000       19 17511670 17511864 195 +      
ENSG00000130313 E005 14.8081280 0.0011347790 8.810943e-01 9.600391e-01 19 17511865 17511960 96 + 1.192 1.182 -0.036
ENSG00000130313 E006 7.0538436 0.0021719762 1.686556e-06 7.323891e-05 19 17511961 17512944 984 + 0.450 1.036 2.438
ENSG00000130313 E007 0.9985879 0.0120191561 3.962564e-01 6.809723e-01 19 17512945 17512968 24 + 0.206 0.339 0.964
ENSG00000130313 E008 2.7236730 0.0097996035 7.764821e-01 9.141524e-01 19 17512969 17513244 276 + 0.535 0.576 0.186
ENSG00000130313 E009 6.6114377 0.0021637289 2.312326e-02 1.387007e-01 19 17515742 17516172 431 + 0.694 0.949 1.000
ENSG00000130313 E010 44.2609544 0.0003586172 4.358192e-01 7.122678e-01 19 17516173 17516280 108 + 1.662 1.630 -0.110
ENSG00000130313 E011 1.1258190 0.0145131688 2.819648e-01 5.753873e-01 19 17516371 17516474 104 + 0.206 0.377 1.186
ENSG00000130313 E012 58.6159924 0.0004110877 8.224775e-01 9.355712e-01 19 17517288 17517389 102 + 1.766 1.759 -0.024
ENSG00000130313 E013 81.0576097 0.0002392793 4.614046e-01 7.321819e-01 19 17517710 17517850 141 + 1.886 1.909 0.078
ENSG00000130313 E014 98.1317771 0.0002643238 2.891708e-02 1.594045e-01 19 17520944 17521288 345 + 2.017 1.961 -0.187

Help

Please Click HERE to learn more details about the results from DEXseq.