ENSG00000130479

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000324096 ENSG00000130479 No_inf pgKDN_inf MAP1S protein_coding protein_coding 84.98582 62.42603 98.73408 1.72703 8.532451 0.6613154 47.197541 30.808109 60.473107 0.8640281 1.050948 0.97275394 0.55875000 0.495575 0.631750 0.136175 0.514450490 0.003143513 FALSE TRUE
ENST00000597000 ENSG00000130479 No_inf pgKDN_inf MAP1S protein_coding protein_coding 84.98582 62.42603 98.73408 1.72703 8.532451 0.6613154 8.162258 0.000000 17.805673 0.0000000 5.981960 10.79893127 0.07494167 0.000000 0.166375 0.166375 0.003143513 0.003143513 FALSE FALSE
ENST00000597681 ENSG00000130479 No_inf pgKDN_inf MAP1S protein_coding protein_coding_CDS_not_defined 84.98582 62.42603 98.73408 1.72703 8.532451 0.6613154 10.941610 8.933074 8.549318 1.0843206 3.664132 -0.06327497 0.12797500 0.142550 0.080100 -0.062450 0.659972140 0.003143513 FALSE FALSE
ENST00000601097 ENSG00000130479 No_inf pgKDN_inf MAP1S protein_coding retained_intron 84.98582 62.42603 98.73408 1.72703 8.532451 0.6613154 10.656404 16.175614 3.900778 2.0230056 2.131375 -2.04918443 0.14182500 0.257025 0.038900 -0.218125 0.016890689 0.003143513   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000130479 E001 0.1176306 1.176916e-02 8.789951e-01   19 17719242 17719375 134 + 0.077 0.000 -10.241
ENSG00000130479 E002 0.0000000       19 17719480 17719483 4 +      
ENSG00000130479 E003 0.3625236 1.837394e-01 9.593467e-01   19 17719484 17719485 2 + 0.143 0.117 -0.334
ENSG00000130479 E004 5.3520553 2.805945e-03 7.767538e-01 9.142271e-01 19 17719486 17719496 11 + 0.782 0.816 0.135
ENSG00000130479 E005 28.6268760 4.807871e-04 5.416667e-01 7.892699e-01 19 17719497 17719620 124 + 1.477 1.444 -0.111
ENSG00000130479 E006 0.3816610 4.158245e-02 4.304021e-02   19 17719771 17719780 10 + 0.000 0.284 13.614
ENSG00000130479 E007 0.5085150 1.606529e-02 1.416063e-02 1.010104e-01 19 17719781 17719875 95 + 0.000 0.349 14.198
ENSG00000130479 E008 0.3642603 2.087101e-01 9.704756e-01   19 17719876 17719966 91 + 0.143 0.117 -0.336
ENSG00000130479 E009 0.3712766 2.240618e-01 3.947189e-01   19 17720086 17720135 50 + 0.077 0.209 1.666
ENSG00000130479 E010 0.2441403 1.625959e-02 7.227638e-01   19 17720136 17720153 18 + 0.077 0.117 0.665
ENSG00000130479 E011 0.1170040 1.170627e-02 8.789857e-01   19 17720156 17720160 5 + 0.077 0.000 -12.265
ENSG00000130479 E012 0.0000000       19 17720161 17720163 3 +      
ENSG00000130479 E013 0.0000000       19 17720164 17720190 27 +      
ENSG00000130479 E014 0.0000000       19 17720191 17720200 10 +      
ENSG00000130479 E015 0.4904501 1.587121e-02 6.513144e-01   19 17720201 17720343 143 + 0.143 0.209 0.665
ENSG00000130479 E016 0.2455571 1.639652e-02 7.230580e-01   19 17720344 17720430 87 + 0.077 0.117 0.665
ENSG00000130479 E017 0.2356421 1.566850e-02 4.431354e-01   19 17720431 17720553 123 + 0.143 0.000 -13.196
ENSG00000130479 E018 0.1186381 1.184378e-02 8.789734e-01   19 17720554 17720591 38 + 0.077 0.000 -12.263
ENSG00000130479 E019 0.7157354 2.587952e-02 2.527999e-01 5.441216e-01 19 17720724 17720751 28 + 0.295 0.117 -1.656
ENSG00000130479 E020 0.9697257 4.653543e-02 9.444448e-01 9.845722e-01 19 17720752 17720820 69 + 0.295 0.284 -0.071
ENSG00000130479 E021 0.6076104 2.356789e-02 9.564578e-01 9.896542e-01 19 17720821 17720935 115 + 0.199 0.209 0.080
ENSG00000130479 E022 17.0800374 9.065670e-04 4.168495e-01 6.966560e-01 19 17720936 17720985 50 + 1.272 1.215 -0.199
ENSG00000130479 E023 24.5912116 5.781753e-04 3.284795e-01 6.210162e-01 19 17720986 17721037 52 + 1.423 1.365 -0.198
ENSG00000130479 E024 0.6165488 1.838365e-02 3.446159e-01 6.358060e-01 19 17721251 17721463 213 + 0.143 0.284 1.250
ENSG00000130479 E025 32.1202913 5.336462e-04 4.633337e-01 7.332797e-01 19 17724126 17724208 83 + 1.527 1.490 -0.127
ENSG00000130479 E026 0.0000000       19 17725030 17725048 19 +      
ENSG00000130479 E027 23.2205408 8.727941e-03 7.179769e-01 8.865073e-01 19 17725049 17725096 48 + 1.365 1.393 0.099
ENSG00000130479 E028 32.5229830 8.159207e-03 6.732687e-01 8.646967e-01 19 17725097 17725189 93 + 1.527 1.503 -0.083
ENSG00000130479 E029 337.3643180 6.708546e-05 4.824108e-03 4.827151e-02 19 17725829 17727288 1460 + 2.536 2.499 -0.123
ENSG00000130479 E030 59.7025613 2.652539e-04 5.185587e-01 7.735140e-01 19 17727289 17727437 149 + 1.784 1.761 -0.078
ENSG00000130479 E031 38.6485902 5.244606e-03 1.380576e-01 3.953929e-01 19 17727438 17727496 59 + 1.554 1.639 0.290
ENSG00000130479 E032 136.9329659 1.259363e-04 3.419246e-02 1.764049e-01 19 17727497 17728112 616 + 2.109 2.163 0.181
ENSG00000130479 E033 38.9949169 7.357777e-04 8.641237e-01 9.529443e-01 19 17728113 17728147 35 + 1.590 1.600 0.035
ENSG00000130479 E034 30.3747510 5.085771e-04 7.916864e-01 9.203124e-01 19 17728148 17728172 25 + 1.482 1.499 0.056
ENSG00000130479 E035 1.6156051 8.305381e-03 2.835629e-02 1.575539e-01 19 17728738 17728981 244 + 0.250 0.577 1.835
ENSG00000130479 E036 3.8797677 3.684289e-03 2.381180e-06 9.848663e-05 19 17733020 17733192 173 + 0.336 0.940 2.724
ENSG00000130479 E037 28.7798697 4.673131e-04 9.925711e-01 1.000000e+00 19 17733193 17733280 88 + 1.465 1.468 0.009
ENSG00000130479 E038 60.0815220 1.084832e-02 5.836290e-01 8.147532e-01 19 17733281 17733428 148 + 1.766 1.795 0.097
ENSG00000130479 E039 1.4622245 9.133155e-02 8.842507e-01 9.610847e-01 19 17733429 17733455 27 + 0.373 0.405 0.180
ENSG00000130479 E040 54.1277776 3.898537e-04 4.102463e-01 6.921528e-01 19 17734273 17734513 241 + 1.719 1.754 0.121

Help

Please Click HERE to learn more details about the results from DEXseq.