ENSG00000130511

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000270061 ENSG00000130511 No_inf pgKDN_inf SSBP4 protein_coding protein_coding 141.6865 187.9207 129.6524 15.93818 20.44755 -0.5354408 20.790759 21.34137 24.523242 4.042920 3.382211 0.2004091 0.16472500 0.118400 0.210900 0.092500 0.55635791 0.01599756 FALSE TRUE
ENST00000348495 ENSG00000130511 No_inf pgKDN_inf SSBP4 protein_coding protein_coding 141.6865 187.9207 129.6524 15.93818 20.44755 -0.5354408 19.335904 12.53096 28.892606 4.482758 4.873630 1.2045512 0.14482500 0.063350 0.223050 0.159700 0.25215249 0.01599756 FALSE TRUE
ENST00000601444 ENSG00000130511 No_inf pgKDN_inf SSBP4 protein_coding retained_intron 141.6865 187.9207 129.6524 15.93818 20.44755 -0.5354408 14.111680 32.25017 2.183463 8.577406 1.307810 -3.8784717 0.08512500 0.167325 0.017525 -0.149800 0.01678339 0.01599756 FALSE FALSE
ENST00000625926 ENSG00000130511 No_inf pgKDN_inf SSBP4 protein_coding protein_coding 141.6865 187.9207 129.6524 15.93818 20.44755 -0.5354408 22.461418 31.32979 25.225080 11.413858 17.839133 -0.3125649 0.13465833 0.163025 0.149050 -0.013975 0.81209854 0.01599756   FALSE
MSTRG.14791.4 ENSG00000130511 No_inf pgKDN_inf SSBP4 protein_coding   141.6865 187.9207 129.6524 15.93818 20.44755 -0.5354408 8.365163 10.19007 0.000000 6.142983 0.000000 -9.9943633 0.06982500 0.063500 0.000000 -0.063500 0.82258322 0.01599756 FALSE TRUE
MSTRG.14791.6 ENSG00000130511 No_inf pgKDN_inf SSBP4 protein_coding   141.6865 187.9207 129.6524 15.93818 20.44755 -0.5354408 13.158701 10.16962 18.073482 4.058304 1.376123 0.8289893 0.09912500 0.051075 0.149525 0.098450 0.40783468 0.01599756 FALSE TRUE
MSTRG.14791.8 ENSG00000130511 No_inf pgKDN_inf SSBP4 protein_coding   141.6865 187.9207 129.6524 15.93818 20.44755 -0.5354408 10.293152 16.44050 8.742249 6.143570 5.058913 -0.9104062 0.08061667 0.093975 0.089825 -0.004150 0.85461544 0.01599756 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000130511 E001 0.9802438 0.0603798291 7.755920e-01 9.138060e-01 19 18418864 18419149 286 + 0.321 0.273 -0.326
ENSG00000130511 E002 0.7373580 0.0510572752 7.863739e-01 9.176781e-01 19 18419214 18419335 122 + 0.261 0.219 -0.326
ENSG00000130511 E003 3.4231437 0.0041558327 3.320756e-01 6.242147e-01 19 18419336 18419397 62 + 0.708 0.585 -0.532
ENSG00000130511 E004 7.0570089 0.0024431508 3.148456e-02 1.674974e-01 19 18419398 18419425 28 + 1.014 0.796 -0.828
ENSG00000130511 E005 7.4282855 0.0028586406 4.488364e-02 2.070791e-01 19 18419426 18419429 4 + 1.025 0.825 -0.754
ENSG00000130511 E006 45.4339159 0.0003155630 2.531716e-04 5.072272e-03 19 18419430 18419605 176 + 1.747 1.587 -0.543
ENSG00000130511 E007 22.9414172 0.0005776551 4.169729e-03 4.375295e-02 19 18419606 18419615 10 + 1.466 1.292 -0.603
ENSG00000130511 E008 23.0536004 0.0005958617 2.067097e-03 2.621457e-02 19 18419616 18419623 8 + 1.474 1.287 -0.647
ENSG00000130511 E009 32.5837264 0.0004823134 4.613866e-04 8.209971e-03 19 18419624 18419648 25 + 1.616 1.435 -0.618
ENSG00000130511 E010 55.5777991 0.0002575774 1.223063e-01 3.699582e-01 19 18419649 18419707 59 + 1.781 1.721 -0.204
ENSG00000130511 E011 0.9888329 0.0119595819 7.000520e-01 8.777136e-01 19 18420103 18420124 22 + 0.261 0.321 0.411
ENSG00000130511 E012 16.1465202 0.0009455159 1.107666e-08 7.829734e-07 19 18422470 18423294 825 + 0.910 1.371 1.661
ENSG00000130511 E013 4.5052528 0.0031946994 1.899637e-03 2.460614e-02 19 18425909 18426039 131 + 0.465 0.866 1.725
ENSG00000130511 E014 1.7585429 0.0076673838 1.709431e-02 1.143025e-01 19 18426040 18426083 44 + 0.190 0.559 2.260
ENSG00000130511 E015 8.4093163 0.0124710209 7.735208e-06 2.737472e-04 19 18427078 18427350 273 + 0.604 1.122 2.023
ENSG00000130511 E016 73.0562385 0.0002056130 9.444254e-01 9.845722e-01 19 18427351 18427423 73 + 1.865 1.864 -0.004
ENSG00000130511 E017 60.1577007 0.0114392528 5.431871e-01 7.901845e-01 19 18427752 18427813 62 + 1.801 1.767 -0.113
ENSG00000130511 E018 71.3802867 0.0043143930 6.091854e-01 8.299567e-01 19 18427898 18427982 85 + 1.867 1.846 -0.072
ENSG00000130511 E019 73.6936097 0.0065632751 8.465350e-01 9.455866e-01 19 18430841 18430930 90 + 1.864 1.872 0.028
ENSG00000130511 E020 25.5445363 0.0005275966 1.635671e-02 1.111642e-01 19 18431353 18431418 66 + 1.493 1.355 -0.477
ENSG00000130511 E021 1.0147640 0.0113287730 5.351163e-03 5.204862e-02 19 18431645 18431646 2 + 0.000 0.439 12.647
ENSG00000130511 E022 44.3956370 0.0046413943 8.675453e-01 9.544537e-01 19 18431647 18431671 25 + 1.646 1.657 0.036
ENSG00000130511 E023 51.9957304 0.0003147382 8.741120e-01 9.569878e-01 19 18431672 18431706 35 + 1.723 1.717 -0.017
ENSG00000130511 E024 1.0153319 0.0743760477 8.399705e-03 7.147833e-02 19 18431707 18431792 86 + 0.000 0.439 12.647
ENSG00000130511 E025 45.9054250 0.0003072869 7.355494e-01 8.951505e-01 19 18431793 18431812 20 + 1.657 1.673 0.056
ENSG00000130511 E026 60.0562316 0.0002876290 8.424642e-01 9.435696e-01 19 18431813 18431862 50 + 1.776 1.785 0.031
ENSG00000130511 E027 68.0959483 0.0024733531 6.093106e-01 8.300618e-01 19 18432000 18432066 67 + 1.845 1.826 -0.064
ENSG00000130511 E028 41.1613618 0.0018053725 6.261711e-01 8.393457e-01 19 18432067 18432070 4 + 1.633 1.611 -0.075
ENSG00000130511 E029 68.6555176 0.0002659159 8.527818e-01 9.480549e-01 19 18432147 18432199 53 + 1.833 1.842 0.028
ENSG00000130511 E030 46.1760055 0.0006834340 6.025836e-01 8.265757e-01 19 18432200 18432214 15 + 1.654 1.679 0.085
ENSG00000130511 E031 65.6134039 0.0053007237 7.519894e-01 9.023873e-01 19 18432559 18432604 46 + 1.808 1.826 0.061
ENSG00000130511 E032 1.4786188 0.0085854582 8.563771e-01 9.495498e-01 19 18432605 18432699 95 + 0.375 0.403 0.160
ENSG00000130511 E033 68.2462669 0.0054666654 5.058394e-01 7.646127e-01 19 18432700 18432735 36 + 1.816 1.850 0.115
ENSG00000130511 E034 82.0681103 0.0006825561 8.522417e-01 9.477921e-01 19 18432829 18432883 55 + 1.910 1.918 0.027
ENSG00000130511 E035 86.6231118 0.0002676126 7.098869e-01 8.826576e-01 19 18432973 18433043 71 + 1.930 1.944 0.045
ENSG00000130511 E036 2.5651244 0.0367708429 4.951664e-01 7.564454e-01 19 18433044 18433100 57 + 0.604 0.503 -0.463
ENSG00000130511 E037 78.9715317 0.0001850459 1.988542e-01 4.803386e-01 19 18433135 18433213 79 + 1.872 1.917 0.151
ENSG00000130511 E038 6.7173873 0.0027329150 1.373182e-02 9.876141e-02 19 18433275 18433584 310 + 0.708 0.979 1.053
ENSG00000130511 E039 56.0319768 0.0002924409 5.729015e-01 8.085958e-01 19 18433585 18433613 29 + 1.763 1.742 -0.072
ENSG00000130511 E040 2.1145545 0.0067005144 2.129319e-01 4.981250e-01 19 18433614 18433652 39 + 0.375 0.559 0.937
ENSG00000130511 E041 80.9710846 0.0011254658 7.982265e-02 2.899875e-01 19 18433710 18433817 108 + 1.942 1.882 -0.203
ENSG00000130511 E042 45.3661469 0.0013130969 2.245653e-01 5.120786e-01 19 18433818 18433932 115 + 1.627 1.685 0.198
ENSG00000130511 E043 59.3562712 0.0004425023 3.391885e-06 1.341187e-04 19 18433933 18434216 284 + 1.657 1.847 0.643
ENSG00000130511 E044 82.4770239 0.0016043375 1.424764e-01 4.016685e-01 19 18434217 18434562 346 + 1.884 1.939 0.184

Help

Please Click HERE to learn more details about the results from DEXseq.