ENSG00000130559

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000312405 ENSG00000130559 No_inf pgKDN_inf CAMSAP1 protein_coding protein_coding 10.65652 8.287071 12.76572 0.5472085 1.24373 0.6227306 4.533894 1.269032 6.1744925 0.5134178 0.8836697 2.273603 0.3998583 0.14985 0.48705 0.3372 0.150398082 0.004148328 FALSE TRUE
ENST00000389532 ENSG00000130559 No_inf pgKDN_inf CAMSAP1 protein_coding protein_coding 10.65652 8.287071 12.76572 0.5472085 1.24373 0.6227306 3.149065 1.416105 4.8433825 0.5316234 1.1326467 1.766911 0.2863833 0.17845 0.38815 0.2097 0.497431992 0.004148328 FALSE TRUE
MSTRG.29494.1 ENSG00000130559 No_inf pgKDN_inf CAMSAP1 protein_coding   10.65652 8.287071 12.76572 0.5472085 1.24373 0.6227306 2.329316 5.070984 0.6985209 0.5376860 0.6985209 -2.842226 0.2637000 0.61795 0.06105 -0.5569 0.004148328 0.004148328 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000130559 E001 0.1265070 0.0122325281 4.277224e-01   9 135808475 135808486 12 - 0.000 0.106 8.762
ENSG00000130559 E002 41.9261099 0.0047649974 5.703767e-07 2.804257e-05 9 135808487 135809580 1094 - 1.492 1.753 0.886
ENSG00000130559 E003 57.3141264 0.0002745642 8.891171e-01 9.630018e-01 9 135809581 135810422 842 - 1.766 1.763 -0.009
ENSG00000130559 E004 9.0258424 0.0049999411 8.521178e-01 9.477464e-01 9 135810423 135810489 67 - 1.006 0.991 -0.055
ENSG00000130559 E005 20.7237264 0.0007415169 6.042635e-02 2.466570e-01 9 135810490 135810680 191 - 1.276 1.397 0.422
ENSG00000130559 E006 44.7553986 0.0003852419 8.892138e-01 9.630293e-01 9 135810681 135811095 415 - 1.655 1.664 0.029
ENSG00000130559 E007 38.1834958 0.0004486648 6.649335e-02 2.597981e-01 9 135811096 135811512 417 - 1.549 1.637 0.300
ENSG00000130559 E008 5.0537981 0.0032166589 7.131392e-02 2.705549e-01 9 135811513 135811514 2 - 0.672 0.881 0.834
ENSG00000130559 E009 13.6934191 0.0010250491 4.100958e-01 6.921467e-01 9 135811515 135811611 97 - 1.135 1.200 0.234
ENSG00000130559 E010 13.2533944 0.0029270045 5.263209e-01 7.787346e-01 9 135815097 135815215 119 - 1.174 1.126 -0.171
ENSG00000130559 E011 10.5098515 0.0157523839 4.646038e-01 7.340405e-01 9 135815890 135816005 116 - 1.024 1.099 0.270
ENSG00000130559 E012 0.3727544 0.0168187310 4.524684e-01   9 135817788 135817847 60 - 0.086 0.190 1.337
ENSG00000130559 E013 6.9047879 0.0627165535 4.178573e-01 6.976627e-01 9 135817977 135818079 103 - 0.946 0.831 -0.439
ENSG00000130559 E014 0.0000000       9 135818080 135818171 92 -      
ENSG00000130559 E015 12.6995237 0.0018788873 5.709881e-01 8.072471e-01 9 135818408 135818616 209 - 1.113 1.161 0.170
ENSG00000130559 E016 0.1268540 0.0122875599 4.276092e-01   9 135818617 135818647 31 - 0.000 0.106 11.133
ENSG00000130559 E017 7.6800347 0.0047166786 9.836191e-01 9.986903e-01 9 135819010 135819146 137 - 0.936 0.940 0.015
ENSG00000130559 E018 92.8982508 0.0001922982 3.186237e-04 6.102505e-03 9 135820839 135823260 2422 - 2.014 1.915 -0.335
ENSG00000130559 E019 6.1347859 0.0024930342 5.656011e-03 5.412550e-02 9 135823950 135824034 85 - 0.967 0.660 -1.211
ENSG00000130559 E020 6.2386386 0.0026355350 6.998875e-01 8.776315e-01 9 135824789 135824880 92 - 0.838 0.881 0.167
ENSG00000130559 E021 0.0000000       9 135826125 135826409 285 -      
ENSG00000130559 E022 9.0355998 0.0015956975 7.836972e-01 9.167836e-01 9 135827407 135827584 178 - 0.987 1.015 0.102
ENSG00000130559 E023 0.0000000       9 135849857 135850136 280 -      
ENSG00000130559 E024 5.0811254 0.0028637880 1.488381e-01 4.109258e-01 9 135850137 135850233 97 - 0.851 0.686 -0.663
ENSG00000130559 E025 6.7853904 0.0019615731 1.917679e-01 4.714778e-01 9 135850322 135850461 140 - 0.946 0.813 -0.511
ENSG00000130559 E026 6.4160718 0.0024357944 1.266467e-01 3.772750e-01 9 135862467 135862608 142 - 0.936 0.775 -0.622
ENSG00000130559 E027 0.0000000       9 135865248 135865331 84 -      
ENSG00000130559 E028 0.0000000       9 135865332 135865364 33 -      
ENSG00000130559 E029 0.0000000       9 135866379 135866455 77 -      
ENSG00000130559 E030 3.9761810 0.0086663402 4.871646e-02 2.174701e-01 9 135866456 135866536 81 - 0.794 0.541 -1.078
ENSG00000130559 E031 4.9408104 0.0304017460 8.058991e-02 2.916942e-01 9 135881633 135881794 162 - 0.864 0.634 -0.936
ENSG00000130559 E032 3.0817842 0.0049801009 3.854795e-05 1.066724e-03 9 135882816 135882937 122 - 0.794 0.190 -3.248
ENSG00000130559 E033 2.5410294 0.0058962108 3.097439e-01 6.030473e-01 9 135882938 135883078 141 - 0.607 0.466 -0.663
ENSG00000130559 E034 3.9121159 0.0037693082 7.757878e-01 9.138656e-01 9 135907000 135907546 547 - 0.672 0.710 0.156

Help

Please Click HERE to learn more details about the results from DEXseq.