ENSG00000130560

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000371756 ENSG00000130560 No_inf pgKDN_inf UBAC1 protein_coding protein_coding 41.93484 38.82366 43.64308 0.8375528 1.063924 0.1687756 33.450620 24.952142 39.270002 1.5324209 1.6633839 0.6540532 0.7933333 0.645750 0.899250 0.253500 4.819559e-04 5.520794e-07 FALSE TRUE
MSTRG.29492.1 ENSG00000130560 No_inf pgKDN_inf UBAC1 protein_coding   41.93484 38.82366 43.64308 0.8375528 1.063924 0.1687756 2.840973 6.344962 0.000000 1.9534155 0.0000000 -9.3117396 0.0701500 0.160825 0.000000 -0.160825 5.520794e-07 5.520794e-07 FALSE TRUE
MSTRG.29492.4 ENSG00000130560 No_inf pgKDN_inf UBAC1 protein_coding   41.93484 38.82366 43.64308 0.8375528 1.063924 0.1687756 4.077505 5.367593 2.728445 0.9362605 0.2480953 -0.9736037 0.0986000 0.137775 0.062775 -0.075000 3.605801e-01 5.520794e-07 TRUE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000130560 E001 0.126507 0.0122686476 5.028106e-01   9 135932966 135932968 3 - 0.000 0.098 9.897
ENSG00000130560 E002 11.241799 0.0012556917 7.667892e-01 0.9095904503 9 135932969 135933041 73 - 1.099 1.076 -0.085
ENSG00000130560 E003 107.460377 0.0001759088 5.750099e-01 0.8096645647 9 135933042 135933515 474 - 2.042 2.029 -0.044
ENSG00000130560 E004 39.397480 0.0077143409 1.658390e-01 0.4357422846 9 135938222 135938339 118 - 1.564 1.645 0.275
ENSG00000130560 E005 18.947265 0.0034540805 7.184685e-02 0.2718717285 9 135938340 135938360 21 - 1.232 1.358 0.442
ENSG00000130560 E006 26.323121 0.0005422605 2.984821e-02 0.1625437821 9 135939673 135939731 59 - 1.370 1.494 0.429
ENSG00000130560 E007 16.065018 0.0234585272 4.902872e-01 0.7529155543 9 135939732 135939759 28 - 1.201 1.261 0.214
ENSG00000130560 E008 0.726971 0.0139064081 4.624105e-01 0.7327972644 9 135942100 135942161 62 - 0.289 0.178 -0.896
ENSG00000130560 E009 1.218523 0.2477718409 6.916620e-01 0.8736743933 9 135942162 135942289 128 - 0.383 0.304 -0.482
ENSG00000130560 E010 48.336251 0.0035630984 2.343951e-02 0.1399055317 9 135945028 135945250 223 - 1.743 1.637 -0.358
ENSG00000130560 E011 18.771620 0.0190560243 1.098778e-05 0.0003713125 9 135945251 135945888 638 - 1.056 1.449 1.386
ENSG00000130560 E012 40.099207 0.0064982341 1.316191e-01 0.3848808819 9 135945889 135945997 109 - 1.652 1.572 -0.275
ENSG00000130560 E013 31.835704 0.0088015445 3.041994e-01 0.5976416544 9 135946269 135946371 103 - 1.547 1.483 -0.218
ENSG00000130560 E014 1.236085 0.0452207626 4.793942e-01 0.7451624142 9 135946372 135946410 39 - 0.289 0.402 0.688
ENSG00000130560 E015 2.273856 0.0086539558 2.471535e-05 0.0007393222 9 135946944 135947220 277 - 0.092 0.725 4.191
ENSG00000130560 E016 2.619199 0.0071709931 1.010319e-02 0.0808465209 9 135947516 135947797 282 - 0.339 0.704 1.782
ENSG00000130560 E017 24.693424 0.0223907870 9.238612e-02 0.3156159372 9 135947798 135947876 79 - 1.471 1.339 -0.458
ENSG00000130560 E018 15.293351 0.0010343149 9.482506e-01 0.9865400855 9 135947877 135947905 29 - 1.213 1.210 -0.012
ENSG00000130560 E019 0.000000       9 135947906 135948044 139 -      
ENSG00000130560 E020 21.933036 0.0006449760 1.781829e-01 0.4529442642 9 135953680 135953753 74 - 1.399 1.318 -0.283
ENSG00000130560 E021 0.126854 0.0123002657 5.027932e-01   9 135953754 135953893 140 - 0.000 0.098 12.094
ENSG00000130560 E022 29.751551 0.0007944076 2.030457e-01 0.4856516541 9 135955295 135955415 121 - 1.520 1.453 -0.229
ENSG00000130560 E023 35.198947 0.0010478429 8.969755e-01 0.9660425312 9 135961025 135961373 349 - 1.561 1.556 -0.016

Help

Please Click HERE to learn more details about the results from DEXseq.