ENSG00000130695

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000252992 ENSG00000130695 No_inf pgKDN_inf CEP85 protein_coding protein_coding 11.76937 9.525092 14.01056 0.5040452 0.4939184 0.5562249 0.6236062 1.870819 0.0000000 1.09157624 0.0000000 -7.5552169 0.06877500 0.206325 0.000000 -0.206325 4.556230e-01 8.320646e-09 FALSE TRUE
ENST00000451429 ENSG00000130695 No_inf pgKDN_inf CEP85 protein_coding protein_coding 11.76937 9.525092 14.01056 0.5040452 0.4939184 0.5562249 5.9760092 1.702828 8.2340817 1.06706694 0.3745542 2.2669785 0.48741667 0.178725 0.587300 0.408575 1.559493e-01 8.320646e-09 FALSE TRUE
ENST00000453146 ENSG00000130695 No_inf pgKDN_inf CEP85 protein_coding protein_coding 11.76937 9.525092 14.01056 0.5040452 0.4939184 0.5562249 1.4454895 3.500826 0.0000000 0.44558146 0.0000000 -8.4556665 0.14196667 0.363850 0.000000 -0.363850 8.320646e-09 8.320646e-09 FALSE TRUE
ENST00000468163 ENSG00000130695 No_inf pgKDN_inf CEP85 protein_coding protein_coding_CDS_not_defined 11.76937 9.525092 14.01056 0.5040452 0.4939184 0.5562249 0.4587365 1.123041 0.2531687 0.53357578 0.2531687 -2.1061400 0.04299167 0.111450 0.017525 -0.093925 4.064485e-01 8.320646e-09   FALSE
ENST00000469609 ENSG00000130695 No_inf pgKDN_inf CEP85 protein_coding protein_coding_CDS_not_defined 11.76937 9.525092 14.01056 0.5040452 0.4939184 0.5562249 2.3074461 0.000000 4.7649554 0.00000000 0.5051705 8.8993435 0.17274167 0.000000 0.341100 0.341100 8.877987e-08 8.320646e-09 FALSE TRUE
ENST00000491670 ENSG00000130695 No_inf pgKDN_inf CEP85 protein_coding protein_coding_CDS_not_defined 11.76937 9.525092 14.01056 0.5040452 0.4939184 0.5562249 0.9580867 1.327579 0.7583505 0.07680592 0.1770726 -0.7997874 0.08610000 0.139700 0.054025 -0.085675 4.087083e-01 8.320646e-09 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000130695 E001 0.1186381 0.0117915402 0.8731095765   1 26234200 26234201 2 + 0.077 0.000 -7.575
ENSG00000130695 E002 2.5243428 0.0059151701 0.1460634592 0.407056624 1 26234202 26234310 109 + 0.615 0.404 -1.022
ENSG00000130695 E003 3.4774570 0.0049117023 0.0370924368 0.185493138 1 26239762 26239838 77 + 0.739 0.454 -1.283
ENSG00000130695 E004 3.9805000 0.0050182652 0.3090070482 0.602344075 1 26244166 26244318 153 + 0.739 0.610 -0.546
ENSG00000130695 E005 0.0000000       1 26254578 26254832 255 +      
ENSG00000130695 E006 22.7649952 0.0006797745 0.2658716513 0.559329159 1 26255171 26255865 695 + 1.394 1.328 -0.231
ENSG00000130695 E007 3.3851545 0.0871029307 0.4897072921 0.752617777 1 26257597 26257672 76 + 0.673 0.576 -0.423
ENSG00000130695 E008 4.8616651 0.0028779868 0.8824700633 0.960462636 1 26257673 26257730 58 + 0.754 0.772 0.071
ENSG00000130695 E009 7.8383187 0.0033303740 0.0714416630 0.270846540 1 26258143 26258260 118 + 0.860 1.035 0.656
ENSG00000130695 E010 9.2569825 0.0015953774 0.4115898717 0.693137229 1 26259617 26259802 186 + 0.972 1.047 0.274
ENSG00000130695 E011 6.4669852 0.0021700173 0.3396673046 0.631367686 1 26268483 26268635 153 + 0.823 0.923 0.383
ENSG00000130695 E012 0.0000000       1 26269290 26269364 75 +      
ENSG00000130695 E013 7.3038423 0.0020065100 0.6551648439 0.855371162 1 26269460 26269614 155 + 0.893 0.939 0.170
ENSG00000130695 E014 2.6591904 0.0069894933 0.4985619772 0.758988418 1 26271014 26271027 14 + 0.594 0.498 -0.444
ENSG00000130695 E015 5.1372786 0.0029616834 0.2493277926 0.540194980 1 26271028 26271107 80 + 0.723 0.854 0.518
ENSG00000130695 E016 3.6095419 0.0043354773 0.0002712179 0.005358193 1 26271465 26272020 556 + 0.408 0.872 2.048
ENSG00000130695 E017 3.6743894 0.0040532739 0.2186832504 0.505332580 1 26272021 26272071 51 + 0.594 0.749 0.656
ENSG00000130695 E018 0.7525292 0.0566983545 0.0313424967 0.167087696 1 26272072 26272393 322 + 0.077 0.404 2.978
ENSG00000130695 E019 6.3023018 0.0023374103 0.7298568920 0.892448119 1 26274964 26275071 108 + 0.871 0.835 -0.141
ENSG00000130695 E020 13.4029628 0.0011861429 0.1015132221 0.332665823 1 26276535 26276760 226 + 1.199 1.070 -0.463
ENSG00000130695 E021 0.7357890 0.0156215174 0.5846945444 0.815396040 1 26277133 26277135 3 + 0.200 0.284 0.656
ENSG00000130695 E022 93.3679164 0.0002284972 0.6319009115 0.842211826 1 26277136 26278808 1673 + 1.971 1.961 -0.036

Help

Please Click HERE to learn more details about the results from DEXseq.