ENSG00000130713

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000372350 ENSG00000130713 No_inf pgKDN_inf EXOSC2 protein_coding protein_coding_CDS_not_defined 19.8438 14.92483 26.18624 0.6456013 0.6941042 0.8106786 2.4848070 0.000000 7.4544210 0.0000000 1.5993942 9.543887 0.09505000 0.000000 0.285150 0.285150 1.222163e-07 1.222163e-07 FALSE FALSE
ENST00000372358 ENSG00000130713 No_inf pgKDN_inf EXOSC2 protein_coding protein_coding 19.8438 14.92483 26.18624 0.6456013 0.6941042 0.8106786 3.8362091 1.407701 4.1063453 0.8768185 2.3829903 1.537810 0.19309167 0.092425 0.159100 0.066675 1.000000e+00 1.222163e-07 FALSE TRUE
ENST00000491115 ENSG00000130713 No_inf pgKDN_inf EXOSC2 protein_coding nonsense_mediated_decay 19.8438 14.92483 26.18624 0.6456013 0.6941042 0.8106786 0.8850932 1.346816 0.1493826 1.0616552 0.1493826 -3.089660 0.05049167 0.086750 0.005400 -0.081350 7.007759e-01 1.222163e-07 FALSE TRUE
ENST00000688364 ENSG00000130713 No_inf pgKDN_inf EXOSC2 protein_coding retained_intron 19.8438 14.92483 26.18624 0.6456013 0.6941042 0.8106786 0.4915477 0.000000 1.4746430 0.0000000 1.4746430 7.213972 0.01847500 0.000000 0.055425 0.055425 9.073258e-01 1.222163e-07 FALSE TRUE
ENST00000691284 ENSG00000130713 No_inf pgKDN_inf EXOSC2 protein_coding nonsense_mediated_decay 19.8438 14.92483 26.18624 0.6456013 0.6941042 0.8106786 6.6064578 6.016590 6.8919304 0.8891982 1.1582100 0.195658 0.34874167 0.408300 0.261000 -0.147300 5.713771e-01 1.222163e-07 TRUE TRUE
ENST00000693435 ENSG00000130713 No_inf pgKDN_inf EXOSC2 protein_coding nonsense_mediated_decay 19.8438 14.92483 26.18624 0.6456013 0.6941042 0.8106786 1.5573872 3.331661 1.3405011 0.3250773 0.7750941 -1.307070 0.09064167 0.222500 0.049425 -0.173075 1.926246e-01 1.222163e-07 FALSE TRUE
ENST00000693610 ENSG00000130713 No_inf pgKDN_inf EXOSC2 protein_coding nonsense_mediated_decay 19.8438 14.92483 26.18624 0.6456013 0.6941042 0.8106786 0.6284001 1.065003 0.3320034 0.4613088 0.2217852 -1.652259 0.03695000 0.071125 0.012975 -0.058150 4.847937e-01 1.222163e-07 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000130713 E001 0.0000000       9 130693721 130693755 35 +      
ENSG00000130713 E002 0.0000000       9 130693756 130693764 9 +      
ENSG00000130713 E003 0.0000000       9 130693765 130693768 4 +      
ENSG00000130713 E004 0.0000000       9 130693769 130693770 2 +      
ENSG00000130713 E005 0.1272623 0.0123402233 0.4498005449   9 130693771 130693774 4 + 0.000 0.104 9.586
ENSG00000130713 E006 0.1272623 0.0123402233 0.4498005449   9 130693775 130693779 5 + 0.000 0.104 11.856
ENSG00000130713 E007 0.1272623 0.0123402233 0.4498005449   9 130693780 130693780 1 + 0.000 0.104 11.856
ENSG00000130713 E008 0.1272623 0.0123402233 0.4498005449   9 130693781 130693785 5 + 0.000 0.104 11.856
ENSG00000130713 E009 0.2541163 0.0164267474 0.1871426888   9 130693786 130693786 1 + 0.000 0.187 12.774
ENSG00000130713 E010 0.3717469 0.0168452397 0.4781374895   9 130693787 130693791 5 + 0.087 0.187 1.278
ENSG00000130713 E011 1.0892425 0.0137542726 0.4659580207 0.73486760 9 130693792 130693805 14 + 0.368 0.257 -0.722
ENSG00000130713 E012 6.9728666 0.0025499503 0.0021355758 0.02683601 9 130693806 130693913 108 + 1.024 0.703 -1.242
ENSG00000130713 E013 0.0000000       9 130695491 130695491 1 +      
ENSG00000130713 E014 13.9134691 0.0009758600 0.0103990046 0.08239442 9 130695492 130695593 102 + 1.253 1.061 -0.685
ENSG00000130713 E015 0.8419966 0.0333263122 0.3670013845 0.65570784 9 130695594 130695606 13 + 0.325 0.187 -1.044
ENSG00000130713 E016 9.7993300 0.0014544485 0.0248660277 0.14495448 9 130697582 130697603 22 + 1.114 0.918 -0.722
ENSG00000130713 E017 10.1648115 0.0015787039 0.0223929973 0.13607327 9 130697604 130697627 24 + 1.129 0.932 -0.722
ENSG00000130713 E018 1.7432113 0.0114574352 0.0546439225 0.23284865 9 130697628 130697939 312 + 0.276 0.568 1.599
ENSG00000130713 E019 1.1067146 0.0993820098 0.5940140124 0.82124405 9 130697940 130698161 222 + 0.276 0.371 0.600
ENSG00000130713 E020 13.6877847 0.0012361847 0.8517682925 0.94757268 9 130698162 130698251 90 + 1.157 1.176 0.071
ENSG00000130713 E021 1.9585886 0.0092800401 0.7254078601 0.88982335 9 130698252 130699328 1077 + 0.444 0.499 0.278
ENSG00000130713 E022 13.6532294 0.0105129594 0.7113522923 0.88333927 9 130699329 130699394 66 + 1.176 1.152 -0.085
ENSG00000130713 E023 6.4140341 0.0649472358 0.1035618141 0.33633425 9 130699395 130700841 1447 + 0.736 0.983 0.955
ENSG00000130713 E024 0.9882686 0.0148198359 0.3425123958 0.63394437 9 130700842 130700866 25 + 0.222 0.371 1.015
ENSG00000130713 E025 12.8429325 0.0012403812 0.5309404886 0.78171922 9 130700867 130700935 69 + 1.114 1.169 0.195
ENSG00000130713 E026 2.2401478 0.0060682726 0.0230535111 0.13853683 9 130700936 130701097 162 + 0.325 0.654 1.656
ENSG00000130713 E027 5.1704791 0.0028194053 0.1341622013 0.38927825 9 130701098 130701558 461 + 0.699 0.873 0.693
ENSG00000130713 E028 6.8105684 0.0021230645 0.5007436757 0.76076552 9 130701559 130702104 546 + 0.921 0.857 -0.243
ENSG00000130713 E029 1.7296867 0.0423644294 0.1902017968 0.46923171 9 130702105 130702133 29 + 0.325 0.535 1.126
ENSG00000130713 E030 6.6169340 0.0027090686 0.3546169952 0.64433895 9 130702134 130702142 9 + 0.831 0.932 0.385
ENSG00000130713 E031 7.4500850 0.0019301675 0.7537343606 0.90311847 9 130702143 130702157 15 + 0.909 0.945 0.136
ENSG00000130713 E032 7.3001836 0.0019788337 0.5469379880 0.79256206 9 130702158 130702187 30 + 0.944 0.889 -0.208
ENSG00000130713 E033 17.2699663 0.0008189002 0.2434650542 0.53347868 9 130702188 130702310 123 + 1.219 1.304 0.298
ENSG00000130713 E034 3.9902848 0.0073021667 0.0009066368 0.01391535 9 130702311 130703052 742 + 0.444 0.873 1.863
ENSG00000130713 E035 7.4058152 0.0021671146 0.0251451310 0.14587259 9 130703053 130703076 24 + 0.802 1.029 0.863
ENSG00000130713 E036 15.4398272 0.0115904353 0.3659351593 0.65447496 9 130703077 130703181 105 + 1.176 1.255 0.277
ENSG00000130713 E037 0.2536433 0.0159526208 0.1873843436   9 130703182 130703550 369 + 0.000 0.187 12.775
ENSG00000130713 E038 39.2480492 0.0003884469 0.3634030379 0.65233555 9 130703694 130703993 300 + 1.620 1.585 -0.119
ENSG00000130713 E039 61.4232834 0.0002577222 0.2509840322 0.54213763 9 130703994 130705516 1523 + 1.810 1.776 -0.114
ENSG00000130713 E040 12.9493751 0.0078139072 0.7376775449 0.89590776 9 130706796 130707288 493 + 1.129 1.161 0.114

Help

Please Click HERE to learn more details about the results from DEXseq.