ENSG00000130726

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000341753 ENSG00000130726 No_inf pgKDN_inf TRIM28 protein_coding protein_coding 183.213 157.471 173.0232 5.707728 9.227973 0.1358705 17.15712 9.607700 21.81177 3.4547906 4.0746388 1.18200435 0.09527500 0.062875 0.128100 0.065225 0.668754458 0.003038101 FALSE TRUE
ENST00000595028 ENSG00000130726 No_inf pgKDN_inf TRIM28 protein_coding retained_intron 183.213 157.471 173.0232 5.707728 9.227973 0.1358705 12.13186 9.733678 10.05390 3.4446334 6.3684328 0.04665063 0.06515833 0.063125 0.055750 -0.007375 0.842887198 0.003038101 FALSE FALSE
ENST00000597136 ENSG00000130726 No_inf pgKDN_inf TRIM28 protein_coding protein_coding 183.213 157.471 173.0232 5.707728 9.227973 0.1358705 13.16768 20.197573 7.98747 2.3005509 3.4868611 -1.33728058 0.07561667 0.129575 0.047750 -0.081825 0.424687848 0.003038101 FALSE TRUE
ENST00000598355 ENSG00000130726 No_inf pgKDN_inf TRIM28 protein_coding retained_intron 183.213 157.471 173.0232 5.707728 9.227973 0.1358705 36.96964 37.811990 34.85241 0.6137689 5.2432094 -0.11755314 0.20555833 0.241375 0.199700 -0.041675 0.736894501 0.003038101 FALSE FALSE
ENST00000600840 ENSG00000130726 No_inf pgKDN_inf TRIM28 protein_coding retained_intron 183.213 157.471 173.0232 5.707728 9.227973 0.1358705 17.98416 21.190913 13.94910 5.4517469 6.5734243 -0.60292010 0.09647500 0.131825 0.077275 -0.054550 0.779138020 0.003038101 FALSE FALSE
MSTRG.15789.4 ENSG00000130726 No_inf pgKDN_inf TRIM28 protein_coding   183.213 157.471 173.0232 5.707728 9.227973 0.1358705 54.19461 32.097101 64.30338 2.2475550 0.9099568 1.00222652 0.29614167 0.205725 0.374925 0.169200 0.003038101 0.003038101 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000130726 E001 0.2356421 0.0156764488 3.551090e-01   19 58544064 58544090 27 + 0.154 0.000 -11.736
ENSG00000130726 E002 0.7086255 0.0281449892 2.402069e-02 0.141913896 19 58544091 58544211 121 + 0.357 0.000 -13.320
ENSG00000130726 E003 1.0868896 0.0112080082 5.585289e-01 0.800148965 19 58544212 58544437 226 + 0.357 0.266 -0.593
ENSG00000130726 E004 0.5978563 0.0152283523 2.899630e-01 0.583654214 19 58544438 58544455 18 + 0.267 0.108 -1.593
ENSG00000130726 E005 0.4791531 0.0236492906 4.759028e-01   19 58544456 58544456 1 + 0.214 0.108 -1.178
ENSG00000130726 E006 2.7795887 0.0121568382 2.296064e-01 0.518247380 19 58544457 58544472 16 + 0.644 0.473 -0.786
ENSG00000130726 E007 20.8457911 0.0006570321 4.604157e-02 0.210369885 19 58544473 58544561 89 + 1.391 1.260 -0.457
ENSG00000130726 E008 62.3403594 0.0002722881 5.534914e-03 0.053288118 19 58544562 58544937 376 + 1.844 1.737 -0.363
ENSG00000130726 E009 43.2604154 0.0003289612 1.327779e-01 0.386884079 19 58544938 58545097 160 + 1.673 1.604 -0.236
ENSG00000130726 E010 0.9874107 0.0607806552 2.937395e-01 0.587203246 19 58545098 58545166 69 + 0.214 0.382 1.144
ENSG00000130726 E011 2.4575340 0.0056105955 2.867405e-01 0.580229681 19 58545167 58545424 258 + 0.464 0.613 0.697
ENSG00000130726 E012 43.3689305 0.0022298128 9.895774e-02 0.328442256 19 58545425 58545537 113 + 1.679 1.598 -0.276
ENSG00000130726 E013 67.5538045 0.0002316618 8.507448e-02 0.301610912 19 58545764 58545896 133 + 1.861 1.797 -0.215
ENSG00000130726 E014 0.6162654 0.0147001635 4.492055e-01 0.723013175 19 58547135 58547139 5 + 0.154 0.266 0.992
ENSG00000130726 E015 4.8352101 0.0029507233 3.298262e-03 0.037114220 19 58547140 58547375 236 + 0.576 0.921 1.407
ENSG00000130726 E016 74.3206285 0.0009165485 4.957961e-02 0.219632591 19 58547376 58547511 136 + 1.906 1.833 -0.245
ENSG00000130726 E017 0.0000000       19 58547559 58547596 38 +      
ENSG00000130726 E018 56.2844108 0.0002924572 1.666491e-02 0.112547583 19 58547597 58547690 94 + 1.797 1.699 -0.330
ENSG00000130726 E019 36.5751695 0.0006759785 3.371972e-01 0.629079875 19 58547691 58547713 23 + 1.594 1.545 -0.166
ENSG00000130726 E020 0.0000000       19 58547762 58547791 30 +      
ENSG00000130726 E021 30.9260671 0.0016223649 9.766175e-02 0.325744516 19 58547792 58547801 10 + 1.542 1.448 -0.321
ENSG00000130726 E022 72.2195989 0.0006323744 2.445969e-02 0.143501450 19 58547802 58547906 105 + 1.898 1.815 -0.280
ENSG00000130726 E023 91.4946221 0.0001659423 4.692515e-02 0.212802582 19 58548034 58548180 147 + 1.991 1.928 -0.211
ENSG00000130726 E024 80.9244393 0.0001886593 5.511086e-02 0.233840716 19 58548294 58548408 115 + 1.939 1.874 -0.218
ENSG00000130726 E025 67.2494114 0.0002432281 3.139609e-01 0.607117340 19 58548486 58548592 107 + 1.848 1.811 -0.126
ENSG00000130726 E026 46.1942270 0.0003998956 7.499260e-01 0.901457506 19 58548740 58548776 37 + 1.665 1.679 0.047
ENSG00000130726 E027 5.0374580 0.0028129077 1.758255e-01 0.449993198 19 58548777 58548861 85 + 0.702 0.857 0.619
ENSG00000130726 E028 32.9199580 0.0005359298 2.476129e-01 0.538351654 19 58548862 58548864 3 + 1.555 1.494 -0.209
ENSG00000130726 E029 35.0323402 0.0005918434 5.733004e-01 0.808762558 19 58548865 58548868 4 + 1.567 1.538 -0.099
ENSG00000130726 E030 42.1591782 0.0006329274 8.919335e-01 0.964135550 19 58548869 58548885 17 + 1.630 1.636 0.021
ENSG00000130726 E031 49.9254350 0.0002938644 3.104762e-01 0.603563900 19 58548886 58548910 25 + 1.685 1.728 0.145
ENSG00000130726 E032 1.5957114 0.0097756083 4.376451e-01 0.713929686 19 58548911 58548987 77 + 0.357 0.473 0.630
ENSG00000130726 E033 184.0773692 0.0001537634 1.780454e-01 0.452811817 19 58548988 58549240 253 + 2.252 2.281 0.098
ENSG00000130726 E034 101.5283325 0.0001483606 7.798944e-01 0.915185969 19 58549331 58549449 119 + 2.005 2.013 0.027
ENSG00000130726 E035 89.7813758 0.0001714879 9.865233e-01 0.999364199 19 58549450 58549555 106 + 1.956 1.956 0.001
ENSG00000130726 E036 85.5818862 0.0004990128 6.387668e-01 0.846301710 19 58549556 58549644 89 + 1.928 1.944 0.052
ENSG00000130726 E037 45.6452683 0.0003865074 3.929040e-01 0.677891443 19 58549645 58549650 6 + 1.649 1.687 0.128
ENSG00000130726 E038 2.6884580 0.0484120308 8.401273e-01 0.942588222 19 58549651 58549736 86 + 0.550 0.582 0.143
ENSG00000130726 E039 122.9625314 0.0001821971 3.445582e-01 0.635742878 19 58549737 58549860 124 + 2.079 2.105 0.085
ENSG00000130726 E040 0.7610560 0.0261767814 3.823467e-03 0.041185314 19 58549861 58549948 88 + 0.000 0.430 14.029
ENSG00000130726 E041 122.3268423 0.0001524222 6.102239e-04 0.010189416 19 58549949 58550035 87 + 2.045 2.137 0.309
ENSG00000130726 E042 3.3664394 0.0042775866 1.222739e-03 0.017474092 19 58550036 58550067 32 + 0.396 0.822 1.922
ENSG00000130726 E043 148.0180096 0.0001225504 9.976838e-05 0.002371248 19 58550147 58550284 138 + 2.126 2.221 0.316
ENSG00000130726 E044 184.2196304 0.0001140557 2.915555e-03 0.033808262 19 58550377 58550722 346 + 2.235 2.300 0.215

Help

Please Click HERE to learn more details about the results from DEXseq.