ENSG00000130734

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000309469 ENSG00000130734 No_inf pgKDN_inf ATG4D protein_coding protein_coding 15.07535 13.39836 14.08299 0.9520904 1.428087 0.07184497 3.4811532 0.000000 7.0765826 0.0000000 0.5434536 9.4689463 0.23562500 0.000000 0.532825 0.532825 5.887925e-09 5.887925e-09 FALSE TRUE
ENST00000586417 ENSG00000130734 No_inf pgKDN_inf ATG4D protein_coding nonsense_mediated_decay 15.07535 13.39836 14.08299 0.9520904 1.428087 0.07184497 2.6789375 3.973485 0.2088587 0.3843740 0.2088587 -4.1859594 0.18143333 0.295200 0.012900 -0.282300 1.936277e-04 5.887925e-09 FALSE TRUE
ENST00000586863 ENSG00000130734 No_inf pgKDN_inf ATG4D protein_coding protein_coding 15.07535 13.39836 14.08299 0.9520904 1.428087 0.07184497 1.5236843 1.071373 1.5946909 0.6664589 0.9529761 0.5694310 0.09036667 0.072100 0.099100 0.027000 9.938221e-01 5.887925e-09 FALSE FALSE
ENST00000588667 ENSG00000130734 No_inf pgKDN_inf ATG4D protein_coding nonsense_mediated_decay 15.07535 13.39836 14.08299 0.9520904 1.428087 0.07184497 1.2973520 1.314942 0.5901701 0.8486790 0.3407553 -1.1424862 0.09321667 0.103275 0.047850 -0.055425 9.552965e-01 5.887925e-09 FALSE TRUE
ENST00000588972 ENSG00000130734 No_inf pgKDN_inf ATG4D protein_coding protein_coding 15.07535 13.39836 14.08299 0.9520904 1.428087 0.07184497 2.2955038 2.851499 0.5645715 1.4731048 0.3323318 -2.3162128 0.14799167 0.228625 0.037725 -0.190900 6.396499e-01 5.887925e-09 FALSE TRUE
ENST00000589753 ENSG00000130734 No_inf pgKDN_inf ATG4D protein_coding nonsense_mediated_decay 15.07535 13.39836 14.08299 0.9520904 1.428087 0.07184497 2.6590489 2.024841 3.8768545 2.0248413 1.2949055 0.9336868 0.16885000 0.130750 0.252475 0.121725 3.813906e-01 5.887925e-09 FALSE TRUE
MSTRG.14508.3 ENSG00000130734 No_inf pgKDN_inf ATG4D protein_coding   15.07535 13.39836 14.08299 0.9520904 1.428087 0.07184497 0.8305499 1.880119 0.1712588 0.6737674 0.1712588 -3.3823543 0.06464167 0.148925 0.017100 -0.131825 3.182724e-01 5.887925e-09 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000130734 E001 0.0000000       19 10543895 10543903 9 +      
ENSG00000130734 E002 0.3806233 0.016185097 0.116462530   19 10543904 10543911 8 + 0.000 0.234 9.948
ENSG00000130734 E003 0.9892386 0.011769108 0.541335784 0.78901502 19 10543912 10543916 5 + 0.245 0.340 0.651
ENSG00000130734 E004 1.1160926 0.010765811 0.368116411 0.65663416 19 10543917 10543917 1 + 0.245 0.385 0.914
ENSG00000130734 E005 3.0578484 0.004534155 0.707183968 0.88116926 19 10543918 10543970 53 + 0.631 0.586 -0.202
ENSG00000130734 E006 11.4580015 0.001436667 0.105546544 0.33987386 19 10543971 10544282 312 + 1.157 1.031 -0.457
ENSG00000130734 E007 2.9437104 0.007602271 0.866432450 0.95399422 19 10544283 10544308 26 + 0.605 0.586 -0.086
ENSG00000130734 E008 2.5808670 0.007543915 0.952813222 0.98834840 19 10544309 10544320 12 + 0.547 0.558 0.051
ENSG00000130734 E009 2.4638630 0.008641533 0.771388600 0.91184122 19 10544321 10544325 5 + 0.515 0.558 0.203
ENSG00000130734 E010 1.5149371 0.009065301 0.002830087 0.03305896 19 10544709 10544782 74 + 0.098 0.558 3.373
ENSG00000130734 E011 7.3921611 0.006751986 0.313174680 0.60640741 19 10544783 10544866 84 + 0.864 0.969 0.399
ENSG00000130734 E012 0.0000000       19 10544867 10544956 90 +      
ENSG00000130734 E013 5.3217240 0.003305850 0.075348861 0.28026157 19 10544957 10544996 40 + 0.680 0.884 0.814
ENSG00000130734 E014 4.6969604 0.003570365 0.154815108 0.42036943 19 10544997 10545009 13 + 0.656 0.826 0.691
ENSG00000130734 E015 9.0642329 0.029501874 0.846827410 0.94564557 19 10545010 10545119 110 + 1.014 0.991 -0.086
ENSG00000130734 E016 3.9992833 0.003832890 0.075352708 0.28026157 19 10545120 10545130 11 + 0.799 0.586 -0.894
ENSG00000130734 E017 9.1871743 0.001627472 0.847603080 0.94598292 19 10546839 10547071 233 + 1.014 1.001 -0.048
ENSG00000130734 E018 2.8155025 0.013345093 0.716600190 0.88573656 19 10547072 10547082 11 + 0.605 0.558 -0.212
ENSG00000130734 E019 2.9577121 0.005698856 0.521375182 0.77535497 19 10547083 10547115 33 + 0.547 0.636 0.399
ENSG00000130734 E020 1.1248429 0.012594746 0.109793618 0.34775716 19 10547116 10547188 73 + 0.177 0.425 1.721
ENSG00000130734 E021 4.0368598 0.004023020 0.706019976 0.88067710 19 10547189 10547253 65 + 0.723 0.681 -0.174
ENSG00000130734 E022 9.3740655 0.023693540 0.296060325 0.58915412 19 10548904 10549028 125 + 0.945 1.068 0.451
ENSG00000130734 E023 5.0306621 0.030649584 0.909943806 0.97146186 19 10549029 10549034 6 + 0.781 0.777 -0.016
ENSG00000130734 E024 7.5845271 0.003240654 0.588668330 0.81752080 19 10551897 10551935 39 + 0.958 0.910 -0.179
ENSG00000130734 E025 8.7908366 0.001770821 0.307001111 0.60021295 19 10551936 10551975 40 + 1.035 0.946 -0.327
ENSG00000130734 E026 1.3594427 0.010181692 0.429925964 0.70793886 19 10551976 10552044 69 + 0.303 0.425 0.721
ENSG00000130734 E027 13.4345704 0.002058575 0.251382268 0.54257807 19 10552045 10552121 77 + 1.201 1.118 -0.296
ENSG00000130734 E028 14.3139044 0.001035273 0.498734968 0.75911922 19 10552205 10552324 120 + 1.208 1.163 -0.160
ENSG00000130734 E029 10.6720528 0.002499809 0.998611003 1.00000000 19 10552885 10553418 534 + 1.064 1.068 0.013

Help

Please Click HERE to learn more details about the results from DEXseq.