ENSG00000130935

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000253247 ENSG00000130935 No_inf pgKDN_inf NOL11 protein_coding protein_coding 25.00199 15.66853 32.81222 0.9842399 1.882621 1.065882 20.4218141 11.346174 26.2587392 0.9086044 0.7858121 1.209870 0.8122167 0.732525 0.807575 0.075050 0.844386186 0.000585376 FALSE TRUE
ENST00000581106 ENSG00000130935 No_inf pgKDN_inf NOL11 protein_coding protein_coding 25.00199 15.66853 32.81222 0.9842399 1.882621 1.065882 1.6050479 0.000000 4.4734985 0.0000000 1.6288494 8.808481 0.0470250 0.000000 0.129800 0.129800 0.000585376 0.000585376 FALSE FALSE
ENST00000584942 ENSG00000130935 No_inf pgKDN_inf NOL11 protein_coding retained_intron 25.00199 15.66853 32.81222 0.9842399 1.882621 1.065882 0.6492587 1.597687 0.0000000 0.6045143 0.0000000 -7.328842 0.0371750 0.098075 0.000000 -0.098075 0.014901294 0.000585376   FALSE
MSTRG.13178.5 ENSG00000130935 No_inf pgKDN_inf NOL11 protein_coding   25.00199 15.66853 32.81222 0.9842399 1.882621 1.065882 1.0483329 2.007491 0.2128454 0.7603879 0.1229248 -3.178447 0.0558000 0.124825 0.006725 -0.118100 0.048137427 0.000585376 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000130935 E001 0.5896065 0.0144113596 0.0856203806 0.302809810 17 67717931 67717935 5 + 0.283 0.000 -11.611
ENSG00000130935 E002 1.1870169 0.0107115990 0.0617216028 0.249635363 17 67717936 67717944 9 + 0.424 0.122 -2.345
ENSG00000130935 E003 2.0314003 0.0070498015 0.0970158719 0.324453031 17 67717945 67717956 12 + 0.553 0.296 -1.398
ENSG00000130935 E004 12.6100378 0.0015509835 0.9246964900 0.977150746 17 67717957 67718088 132 + 1.119 1.126 0.028
ENSG00000130935 E005 0.0000000       17 67719111 67719167 57 +      
ENSG00000130935 E006 0.0000000       17 67719386 67719673 288 +      
ENSG00000130935 E007 17.9302531 0.0373486439 0.9719711119 0.994749188 17 67719674 67719787 114 + 1.266 1.262 -0.017
ENSG00000130935 E008 13.9235961 0.0316421712 0.8680564327 0.954743472 17 67719906 67719962 57 + 1.170 1.147 -0.082
ENSG00000130935 E009 0.1187032 0.0118406787 1.0000000000   17 67720347 67720444 98 + 0.073 0.000 -9.288
ENSG00000130935 E010 11.4589264 0.0015080433 0.1740340461 0.447544569 17 67721378 67721449 72 + 1.125 1.005 -0.434
ENSG00000130935 E011 13.6435278 0.0010168816 0.2505535012 0.541704182 17 67721450 67721526 77 + 1.186 1.093 -0.332
ENSG00000130935 E012 12.9342912 0.0011789985 0.4630076560 0.733107629 17 67722580 67722637 58 + 1.154 1.093 -0.216
ENSG00000130935 E013 10.6615823 0.0013083185 0.8664306800 0.953994219 17 67724049 67724108 60 + 1.060 1.045 -0.054
ENSG00000130935 E014 11.7410252 0.0015257606 0.8350311186 0.940613374 17 67724109 67724193 85 + 1.100 1.082 -0.065
ENSG00000130935 E015 20.1132183 0.0016482363 0.0306002212 0.164596350 17 67726460 67726648 189 + 1.363 1.212 -0.528
ENSG00000130935 E016 0.2435110 0.0161778917 0.6564534258   17 67726649 67727028 380 + 0.073 0.122 0.825
ENSG00000130935 E017 10.6833139 0.0014126012 0.6205305359 0.835919123 17 67734363 67734439 77 + 1.039 1.082 0.157
ENSG00000130935 E018 20.6177826 0.0122262873 0.5844402482 0.815301856 17 67735900 67736023 124 + 1.308 1.346 0.133
ENSG00000130935 E019 0.0000000       17 67736580 67736665 86 +      
ENSG00000130935 E020 16.6245855 0.0009653347 0.5264085038 0.778734557 17 67736666 67736754 89 + 1.216 1.262 0.160
ENSG00000130935 E021 0.1186381 0.0118850971 1.0000000000   17 67737039 67737070 32 + 0.073 0.000 -9.288
ENSG00000130935 E022 18.7912799 0.0007732470 0.9944957984 1.000000000 17 67737071 67737145 75 + 1.284 1.284 0.002
ENSG00000130935 E023 31.3918689 0.0014433203 0.9458511295 0.985412048 17 67737508 67737692 185 + 1.499 1.495 -0.011
ENSG00000130935 E024 0.6076078 0.0169438326 0.8581620164 0.950529033 17 67737693 67737846 154 + 0.191 0.218 0.240
ENSG00000130935 E025 23.2846403 0.0050391507 0.9793075196 0.997487711 17 67737847 67737972 126 + 1.373 1.371 -0.010
ENSG00000130935 E026 45.0098557 0.0043577605 0.7474783691 0.900288831 17 67738122 67738355 234 + 1.644 1.659 0.052
ENSG00000130935 E027 2.9519466 0.0942467023 0.1467283927 0.407816343 17 67738356 67738931 576 + 0.481 0.719 1.065
ENSG00000130935 E028 24.3844357 0.0006829804 0.6078989280 0.829175306 17 67738932 67739010 79 + 1.380 1.411 0.107
ENSG00000130935 E029 14.3239867 0.0010034163 0.6458942290 0.850210974 17 67739516 67739552 37 + 1.159 1.195 0.127
ENSG00000130935 E030 15.5258276 0.0097567213 0.9125198170 0.972187156 17 67739553 67739608 56 + 1.201 1.212 0.039
ENSG00000130935 E031 0.1187032 0.0118406787 1.0000000000   17 67743384 67743478 95 + 0.073 0.000 -9.288
ENSG00000130935 E032 19.0564586 0.0028023756 0.5929362964 0.820557929 17 67743479 67743586 108 + 1.275 1.313 0.131
ENSG00000130935 E033 1.7611849 0.0092364137 0.0001490169 0.003284461 17 67743587 67743742 156 + 0.136 0.691 3.409
ENSG00000130935 E034 33.9104560 0.0004282353 0.7903443319 0.919664104 17 67743743 67743924 182 + 1.535 1.522 -0.046
ENSG00000130935 E035 25.1761667 0.0007000815 0.1772957064 0.451860251 17 67743925 67744531 607 + 1.373 1.453 0.274

Help

Please Click HERE to learn more details about the results from DEXseq.