ENSG00000130985

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000335972 ENSG00000130985 No_inf pgKDN_inf UBA1 protein_coding protein_coding 84.5991 65.03639 93.88853 0.9483119 1.705737 0.5296337 54.262627 29.363861 65.297161 2.2310017 5.6077068 1.15270829 0.62239167 0.451975 0.697725 0.245750 0.07377734 0.02420849 FALSE  
ENST00000377269 ENSG00000130985 No_inf pgKDN_inf UBA1 protein_coding protein_coding 84.5991 65.03639 93.88853 0.9483119 1.705737 0.5296337 3.154820 4.935604 1.900634 0.7669437 0.4773538 -1.37209573 0.04109167 0.075525 0.020025 -0.055500 0.05753595 0.02420849 FALSE  
ENST00000377351 ENSG00000130985 No_inf pgKDN_inf UBA1 protein_coding protein_coding 84.5991 65.03639 93.88853 0.9483119 1.705737 0.5296337 21.120232 23.081451 23.259151 3.1259798 6.4322990 0.01105971 0.25975833 0.353925 0.245700 -0.108225 0.67293662 0.02420849 FALSE  
MSTRG.29919.8 ENSG00000130985 No_inf pgKDN_inf UBA1 protein_coding   84.5991 65.03639 93.88853 0.9483119 1.705737 0.5296337 4.273098 5.914012 2.482448 0.3344365 0.3053388 -1.24901103 0.05470833 0.091025 0.026375 -0.064650 0.02420849 0.02420849 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000130985 E001 1.5471641 0.1114300240 6.561138e-02 2.580533e-01 X 47190861 47190950 90 + 0.527 0.192 -2.083
ENSG00000130985 E002 0.0000000       X 47191399 47191422 24 +      
ENSG00000130985 E003 0.1265070 0.0122952107 4.154837e-01   X 47191423 47191567 145 + 0.000 0.107 9.870
ENSG00000130985 E004 0.4996698 0.0339057528 2.161231e-01   X 47191568 47191734 167 + 0.085 0.264 1.960
ENSG00000130985 E005 0.3709943 0.0166697762 4.374758e-01   X 47193829 47193836 8 + 0.085 0.192 1.375
ENSG00000130985 E006 0.3709943 0.0166697762 4.374758e-01   X 47193837 47193837 1 + 0.085 0.192 1.375
ENSG00000130985 E007 24.8799512 0.0031547068 8.626305e-04 1.338082e-02 X 47193838 47194024 187 + 1.496 1.281 -0.742
ENSG00000130985 E008 22.4320696 0.0061405191 2.077892e-08 1.393893e-06 X 47196236 47197198 963 + 1.143 1.541 1.387
ENSG00000130985 E009 24.6875335 0.0006816499 3.708628e-19 9.303308e-17 X 47197199 47198166 968 + 1.062 1.629 1.979
ENSG00000130985 E010 6.0865926 0.0022417396 3.283911e-04 6.256250e-03 X 47198167 47198308 142 + 0.626 1.020 1.556
ENSG00000130985 E011 3.4374948 0.0226392969 3.314914e-01 6.236400e-01 X 47198309 47198355 47 + 0.579 0.714 0.582
ENSG00000130985 E012 4.0723908 0.0059801143 5.615051e-02 2.362816e-01 X 47198356 47198456 101 + 0.579 0.818 0.996
ENSG00000130985 E013 38.5441767 0.0011115835 3.499381e-05 9.850503e-04 X 47198803 47198919 117 + 1.678 1.469 -0.714
ENSG00000130985 E014 30.6118728 0.0005700315 1.914579e-03 2.474500e-02 X 47199048 47199106 59 + 1.567 1.397 -0.582
ENSG00000130985 E015 53.3457972 0.0028029479 1.563183e-01 4.225577e-01 X 47199209 47199377 169 + 1.761 1.697 -0.218
ENSG00000130985 E016 42.0355011 0.0003459827 8.207373e-02 2.948199e-01 X 47199480 47199614 135 + 1.666 1.587 -0.269
ENSG00000130985 E017 29.8124912 0.0005886983 4.470735e-01 7.212174e-01 X 47200894 47201000 107 + 1.504 1.465 -0.137
ENSG00000130985 E018 42.7762945 0.0003294035 2.433482e-03 2.950707e-02 X 47201276 47201366 91 + 1.697 1.558 -0.474
ENSG00000130985 E019 61.6433528 0.0007575482 1.192593e-02 9.017285e-02 X 47201478 47201610 133 + 1.837 1.739 -0.332
ENSG00000130985 E020 0.0000000       X 47201611 47201611 1 +      
ENSG00000130985 E021 44.9942168 0.0003938853 2.288944e-01 5.176182e-01 X 47202156 47202253 98 + 1.684 1.632 -0.178
ENSG00000130985 E022 60.8691816 0.0002459312 7.059220e-01 8.806424e-01 X 47202358 47202504 147 + 1.782 1.799 0.056
ENSG00000130985 E023 37.2576951 0.0004370810 6.600097e-02 2.587553e-01 X 47202638 47202692 55 + 1.619 1.530 -0.305
ENSG00000130985 E024 58.5701169 0.0003136780 9.138289e-02 3.139671e-01 X 47202693 47202814 122 + 1.802 1.737 -0.220
ENSG00000130985 E025 44.0528151 0.0003803789 3.972561e-01 6.814751e-01 X 47202943 47203047 105 + 1.668 1.632 -0.124
ENSG00000130985 E026 35.0032208 0.0004334242 7.474065e-01 9.002888e-01 X 47203134 47203214 81 + 1.546 1.564 0.062
ENSG00000130985 E027 66.7744965 0.0030405284 8.693993e-01 9.551103e-01 X 47203541 47203696 156 + 1.831 1.826 -0.017
ENSG00000130985 E028 77.7700659 0.0074661143 7.869875e-02 2.875509e-01 X 47205948 47206077 130 + 1.931 1.846 -0.286
ENSG00000130985 E029 49.2950424 0.0003316529 3.272910e-01 6.198291e-01 X 47206078 47206113 36 + 1.717 1.677 -0.136
ENSG00000130985 E030 119.8526439 0.0006309360 1.541874e-01 4.194886e-01 X 47206248 47206444 197 + 2.098 2.059 -0.131
ENSG00000130985 E031 0.9980499 0.0183602673 7.673254e-02 2.832256e-01 X 47206445 47206664 220 + 0.155 0.427 1.960
ENSG00000130985 E032 7.1632197 0.0019934646 5.398152e-03 5.234519e-02 X 47208562 47209622 1061 + 0.758 1.043 1.085
ENSG00000130985 E033 63.2178028 0.0003139583 7.548521e-01 9.035580e-01 X 47209623 47209687 65 + 1.810 1.800 -0.034
ENSG00000130985 E034 109.7717461 0.0001557446 6.683081e-01 8.619436e-01 X 47209928 47210123 196 + 2.047 2.037 -0.034
ENSG00000130985 E035 57.5053020 0.0005522901 8.538101e-01 9.484189e-01 X 47210842 47210916 75 + 1.768 1.762 -0.019
ENSG00000130985 E036 104.1025360 0.0006312713 3.628504e-01 6.519203e-01 X 47211036 47211225 190 + 2.006 2.036 0.100
ENSG00000130985 E037 66.0411639 0.0002113522 3.523557e-02 1.797132e-01 X 47212424 47212512 89 + 1.787 1.866 0.268
ENSG00000130985 E038 86.9891461 0.0005413666 5.323236e-02 2.296460e-01 X 47212771 47212863 93 + 1.912 1.977 0.221
ENSG00000130985 E039 162.7017646 0.0001167195 9.885751e-01 1.000000e+00 X 47212990 47213181 192 + 2.211 2.214 0.008
ENSG00000130985 E040 124.1187295 0.0001367845 5.723094e-01 8.083538e-01 X 47214327 47214428 102 + 2.101 2.088 -0.044
ENSG00000130985 E041 116.2891032 0.0027513843 5.203646e-01 7.747076e-01 X 47214537 47214637 101 + 2.056 2.080 0.080
ENSG00000130985 E042 230.0733287 0.0012342812 5.218517e-05 1.380361e-03 X 47214794 47215128 335 + 2.316 2.412 0.320

Help

Please Click HERE to learn more details about the results from DEXseq.