ENSG00000131051

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000361162 ENSG00000131051 No_inf pgKDN_inf RBM39 protein_coding protein_coding 144.9211 176.0374 120.4057 11.63778 4.388993 -0.5479406 18.574957 20.713712 22.214496 3.5930603 4.11312018 0.1008683 0.13562500 0.121750 0.188600 0.066850 6.851845e-01 1.368255e-11 FALSE TRUE
ENST00000403542 ENSG00000131051 No_inf pgKDN_inf RBM39 protein_coding nonsense_mediated_decay 144.9211 176.0374 120.4057 11.63778 4.388993 -0.5479406 9.146575 16.091778 4.294383 4.9768168 2.48686286 -1.9033417 0.05766667 0.087500 0.033625 -0.053875 4.390285e-01 1.368255e-11 FALSE TRUE
ENST00000434927 ENSG00000131051 No_inf pgKDN_inf RBM39 protein_coding protein_coding 144.9211 176.0374 120.4057 11.63778 4.388993 -0.5479406 9.160413 10.180735 4.776015 6.0165926 3.17597873 -1.0903614 0.06045000 0.054625 0.037175 -0.017450 1.000000e+00 1.368255e-11 FALSE FALSE
ENST00000444878 ENSG00000131051 No_inf pgKDN_inf RBM39 protein_coding nonsense_mediated_decay 144.9211 176.0374 120.4057 11.63778 4.388993 -0.5479406 14.974367 8.695669 19.728608 3.8250449 1.19982313 1.1809932 0.11267500 0.053675 0.164350 0.110675 3.404652e-01 1.368255e-11 FALSE TRUE
ENST00000463004 ENSG00000131051 No_inf pgKDN_inf RBM39 protein_coding retained_intron 144.9211 176.0374 120.4057 11.63778 4.388993 -0.5479406 11.721457 16.431623 8.282398 0.2606959 0.07996948 -0.9874914 0.07987500 0.094375 0.069075 -0.025300 6.337186e-01 1.368255e-11 FALSE TRUE
ENST00000465158 ENSG00000131051 No_inf pgKDN_inf RBM39 protein_coding retained_intron 144.9211 176.0374 120.4057 11.63778 4.388993 -0.5479406 8.508410 15.499759 0.000000 4.6197414 0.00000000 -10.5989605 0.05340000 0.085575 0.000000 -0.085575 1.368255e-11 1.368255e-11 FALSE TRUE
ENST00000495293 ENSG00000131051 No_inf pgKDN_inf RBM39 protein_coding retained_intron 144.9211 176.0374 120.4057 11.63778 4.388993 -0.5479406 6.903646 1.628329 14.082066 1.6283289 2.60878871 3.1045862 0.05285833 0.009425 0.115900 0.106475 3.375227e-03 1.368255e-11 FALSE TRUE
ENST00000496183 ENSG00000131051 No_inf pgKDN_inf RBM39 protein_coding retained_intron 144.9211 176.0374 120.4057 11.63778 4.388993 -0.5479406 7.800920 11.578712 5.538056 0.8085058 0.71120690 -1.0626661 0.05269167 0.066300 0.046325 -0.019975 6.978373e-01 1.368255e-11 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000131051 E001 0.0000000       20 35701347 35701852 506 -      
ENSG00000131051 E002 0.4972804 0.0310611668 5.637904e-01   20 35701853 35702692 840 - 0.115 0.203 0.981
ENSG00000131051 E003 0.5067220 0.0561336766 1.185823e-01 3.637876e-01 20 35702693 35702895 203 - 0.000 0.254 11.089
ENSG00000131051 E004 0.0000000       20 35702896 35703223 328 -      
ENSG00000131051 E005 0.0000000       20 35703224 35703266 43 -      
ENSG00000131051 E006 0.3815350 0.0279002415 2.152674e-01   20 35703267 35703608 342 - 0.000 0.203 10.768
ENSG00000131051 E007 0.0000000       20 35703609 35703609 1 -      
ENSG00000131051 E008 0.2452102 0.0161995333 7.450486e-01   20 35703610 35703610 1 - 0.115 0.079 -0.604
ENSG00000131051 E009 56.3091233 0.0002618439 7.776298e-01 9.146770e-01 20 35703611 35703897 287 - 1.738 1.750 0.039
ENSG00000131051 E010 121.2912946 0.0001456453 3.781834e-04 6.990042e-03 20 35703898 35704325 428 - 2.009 2.110 0.339
ENSG00000131051 E011 21.6991823 0.0006171599 7.610021e-02 2.819104e-01 20 35704326 35704327 2 - 1.267 1.384 0.409
ENSG00000131051 E012 30.9022341 0.0004299278 4.232568e-01 7.025476e-01 20 35704328 35704376 49 - 1.463 1.507 0.152
ENSG00000131051 E013 30.9352984 0.0009011732 6.691096e-01 8.623322e-01 20 35704377 35704399 23 - 1.506 1.483 -0.081
ENSG00000131051 E014 25.8724316 0.0017253246 6.196558e-01 8.354711e-01 20 35704400 35704404 5 - 1.435 1.405 -0.104
ENSG00000131051 E015 99.7022411 0.0001877718 3.903111e-01 6.758826e-01 20 35704405 35704581 177 - 2.006 1.980 -0.088
ENSG00000131051 E016 50.2578116 0.0027955100 4.125368e-01 6.937541e-01 20 35704668 35704702 35 - 1.721 1.682 -0.133
ENSG00000131051 E017 56.4900010 0.0026199073 8.491784e-01 9.464293e-01 20 35704703 35704746 44 - 1.752 1.744 -0.029
ENSG00000131051 E018 1.9616745 0.0089433386 4.122469e-01 6.936353e-01 20 35704747 35705224 478 - 0.533 0.413 -0.604
ENSG00000131051 E019 68.2095590 0.0007400881 7.655665e-01 9.088681e-01 20 35705225 35705261 37 - 1.834 1.823 -0.038
ENSG00000131051 E020 86.9047709 0.0009101253 4.125001e-01 6.937541e-01 20 35705262 35705330 69 - 1.948 1.920 -0.095
ENSG00000131051 E021 0.3711203 0.0165317692 8.813620e-01   20 35705331 35705399 69 - 0.115 0.145 0.396
ENSG00000131051 E022 48.7475100 0.0010088797 1.718152e-01 4.444664e-01 20 35707120 35707135 16 - 1.721 1.660 -0.208
ENSG00000131051 E023 66.7931304 0.0008434236 3.961360e-02 1.930009e-01 20 35707136 35707201 66 - 1.866 1.786 -0.267
ENSG00000131051 E024 56.6195671 0.0002761959 1.606869e-04 3.493142e-03 20 35707202 35707939 738 - 1.642 1.802 0.541
ENSG00000131051 E025 8.3575765 0.0016515237 1.465635e-02 1.034112e-01 20 35707940 35707992 53 - 0.787 1.039 0.953
ENSG00000131051 E026 48.3613020 0.0005172585 2.563154e-05 7.612399e-04 20 35707993 35708803 811 - 1.549 1.745 0.667
ENSG00000131051 E027 13.8304166 0.0009597895 7.818018e-01 9.160998e-01 20 35708804 35708991 188 - 1.145 1.167 0.079
ENSG00000131051 E028 3.3422429 0.2754679637 6.691733e-01 8.623322e-01 20 35708992 35709032 41 - 0.569 0.660 0.399
ENSG00000131051 E029 10.0073072 0.0055774147 3.105520e-04 5.966980e-03 20 35709033 35709223 191 - 0.765 1.137 1.396
ENSG00000131051 E030 45.0770568 0.0051929399 3.320835e-01 6.242147e-01 20 35709224 35709256 33 - 1.682 1.630 -0.175
ENSG00000131051 E031 23.1333359 0.0021922977 1.952850e-03 2.510727e-02 20 35709257 35709274 18 - 1.481 1.285 -0.680
ENSG00000131051 E032 1.1080678 0.0113668924 7.743365e-01 9.132949e-01 20 35709275 35709309 35 - 0.344 0.299 -0.282
ENSG00000131051 E033 19.9066533 0.0009281318 2.550995e-03 3.055780e-02 20 35709310 35710282 973 - 1.164 1.377 0.750
ENSG00000131051 E034 6.2422375 0.0125065327 2.848470e-02 1.580851e-01 20 35710283 35710420 138 - 0.665 0.932 1.059
ENSG00000131051 E035 30.3568041 0.0035523413 9.291138e-08 5.458696e-06 20 35710421 35712341 1921 - 1.238 1.586 1.204
ENSG00000131051 E036 63.7417443 0.0005006683 7.224824e-02 2.726795e-01 20 35713019 35713096 78 - 1.840 1.771 -0.234
ENSG00000131051 E037 15.4865138 0.0008787488 6.149680e-05 1.574166e-03 20 35713097 35713293 197 - 0.975 1.302 1.174
ENSG00000131051 E038 5.2674819 0.0031142908 1.393457e-03 1.931997e-02 20 35713294 35713317 24 - 0.493 0.900 1.718
ENSG00000131051 E039 9.5925498 0.0016486443 1.250674e-02 9.286669e-02 20 35713318 35713407 90 - 0.847 1.091 0.907
ENSG00000131051 E040 11.9585339 0.0012708494 5.481839e-03 5.290936e-02 20 35713408 35713701 294 - 0.932 1.179 0.902
ENSG00000131051 E041 6.6016236 0.0022625228 4.516600e-02 2.077939e-01 20 35713702 35713831 130 - 0.718 0.942 0.874
ENSG00000131051 E042 3.7310145 0.0097118188 1.469774e-01 4.080445e-01 20 35713832 35713857 26 - 0.533 0.730 0.856
ENSG00000131051 E043 103.8605045 0.0002941228 2.569017e-02 1.480494e-01 20 35714185 35714389 205 - 2.048 1.981 -0.226
ENSG00000131051 E044 51.2231773 0.0002766954 8.653595e-03 7.298752e-02 20 35716740 35716805 66 - 1.770 1.660 -0.375
ENSG00000131051 E045 84.0904671 0.0038734800 2.823303e-02 1.571811e-01 20 35721740 35721866 127 - 1.971 1.880 -0.308
ENSG00000131051 E046 34.7281299 0.0007201002 1.024655e-02 8.160620e-02 20 35721867 35721877 11 - 1.617 1.485 -0.451
ENSG00000131051 E047 70.9994163 0.0005837203 6.883992e-02 2.650116e-01 20 35724570 35724675 106 - 1.885 1.818 -0.227
ENSG00000131051 E048 54.3844085 0.0012368575 7.815744e-01 9.160330e-01 20 35724676 35724722 47 - 1.738 1.726 -0.041
ENSG00000131051 E049 44.1729106 0.0020946421 9.257860e-01 9.777382e-01 20 35725038 35725064 27 - 1.645 1.640 -0.015
ENSG00000131051 E050 66.6676022 0.0003893437 2.864481e-01 5.800471e-01 20 35725065 35725123 59 - 1.842 1.802 -0.136
ENSG00000131051 E051 48.1132705 0.0022257207 6.874386e-01 8.710768e-01 20 35725124 35725155 32 - 1.690 1.671 -0.065
ENSG00000131051 E052 40.3982209 0.0029852939 7.789138e-01 9.149984e-01 20 35729312 35729321 10 - 1.595 1.610 0.051
ENSG00000131051 E053 54.7902242 0.0006986802 8.636229e-01 9.528402e-01 20 35729322 35729362 41 - 1.738 1.731 -0.024
ENSG00000131051 E054 35.3099635 0.0004469268 8.578817e-01 9.504376e-01 20 35729363 35729365 3 - 1.542 1.551 0.032
ENSG00000131051 E055 40.4448114 0.0003871120 6.671760e-01 8.615259e-01 20 35729462 35729471 10 - 1.617 1.597 -0.070
ENSG00000131051 E056 58.8569760 0.0003959158 1.865667e-01 4.645347e-01 20 35729472 35729527 56 - 1.796 1.744 -0.178
ENSG00000131051 E057 0.0000000       20 35729528 35729551 24 -      
ENSG00000131051 E058 11.4439986 0.0033097111 4.048000e-01 6.875074e-01 20 35731360 35731915 556 - 1.126 1.054 -0.261
ENSG00000131051 E059 3.1927613 0.0043707223 5.087787e-01 7.669435e-01 20 35731916 35731940 25 - 0.665 0.577 -0.381
ENSG00000131051 E060 35.7739525 0.0004396293 8.612497e-02 3.040001e-01 20 35731941 35731945 5 - 1.604 1.518 -0.295
ENSG00000131051 E061 92.8860803 0.0001737719 2.396300e-01 5.286873e-01 20 35731946 35732044 99 - 1.982 1.945 -0.125
ENSG00000131051 E062 52.0288524 0.0002754822 7.262461e-01 8.904046e-01 20 35732045 35732059 15 - 1.721 1.706 -0.050
ENSG00000131051 E063 68.5522795 0.0002198120 5.177195e-03 5.087953e-02 20 35732060 35732135 76 - 1.890 1.788 -0.345
ENSG00000131051 E064 4.7416270 0.0074766920 4.301436e-02 2.022612e-01 20 35732136 35732806 671 - 0.570 0.830 1.084
ENSG00000131051 E065 1.9854403 0.1513737783 6.841268e-01 8.692355e-01 20 35734186 35734257 72 - 0.399 0.503 0.533
ENSG00000131051 E066 2.2296384 0.0067056178 5.826176e-01 8.140436e-01 20 35734258 35734518 261 - 0.449 0.529 0.396
ENSG00000131051 E067 1.8963505 0.0195467596 4.301088e-03 4.463631e-02 20 35734519 35734766 248 - 0.115 0.577 3.204
ENSG00000131051 E068 0.6339843 0.0152174210 6.034616e-02 2.465129e-01 20 35734767 35734795 29 - 0.000 0.299 11.517
ENSG00000131051 E069 1.1327442 0.0112609919 5.968820e-02 2.450128e-01 20 35734796 35734875 80 - 0.115 0.413 2.396
ENSG00000131051 E070 2.3478698 0.0678388018 8.510613e-01 9.472660e-01 20 35734876 35735081 206 - 0.493 0.529 0.174
ENSG00000131051 E071 0.4890333 0.0157888663 6.781585e-01   20 35736513 35736567 55 - 0.205 0.145 -0.604
ENSG00000131051 E072 0.6072630 0.0147426311 3.643966e-01 6.531442e-01 20 35736568 35736641 74 - 0.280 0.145 -1.189
ENSG00000131051 E073 43.5543441 0.0049198022 8.414107e-03 7.153317e-02 20 35738968 35739017 50 - 1.718 1.577 -0.482
ENSG00000131051 E074 10.5762234 0.0080985748 4.045688e-02 1.951094e-01 20 35739018 35739102 85 - 0.916 1.118 0.742
ENSG00000131051 E075 29.5719524 0.0018733315 1.671868e-01 4.377139e-01 20 35739103 35739392 290 - 1.421 1.502 0.280
ENSG00000131051 E076 22.3217464 0.0127861206 6.986887e-02 2.673886e-01 20 35739393 35739547 155 - 1.260 1.405 0.506
ENSG00000131051 E077 44.0785458 0.0008987266 9.220149e-04 1.411523e-02 20 35739548 35740098 551 - 1.534 1.696 0.552
ENSG00000131051 E078 29.2956939 0.0007619152 1.318572e-02 9.621955e-02 20 35740099 35740457 359 - 1.373 1.518 0.498
ENSG00000131051 E079 11.4245863 0.0011877452 6.803312e-02 2.632099e-01 20 35740458 35740524 67 - 0.975 1.137 0.589
ENSG00000131051 E080 24.5038568 0.0005970914 2.140075e-01 4.991821e-01 20 35740525 35740597 73 - 1.345 1.422 0.267
ENSG00000131051 E081 9.2446305 0.0362249812 1.564697e-02 1.081915e-01 20 35740598 35740823 226 - 0.788 1.090 1.141
ENSG00000131051 E082 37.0093464 0.0003766218 9.029717e-02 3.120451e-01 20 35740824 35740887 64 - 1.617 1.533 -0.286
ENSG00000131051 E083 0.4919310 0.4469607006 7.348942e-01   20 35740952 35740989 38 - 0.205 0.145 -0.605
ENSG00000131051 E084 0.6170510 0.3137591981 8.805779e-01 9.597939e-01 20 35741462 35741487 26 - 0.205 0.203 -0.018
ENSG00000131051 E085 1.3610522 0.0131270321 8.248139e-01 9.364583e-01 20 35741488 35741626 139 - 0.344 0.378 0.204
ENSG00000131051 E086 68.2223814 0.0004870580 2.334426e-02 1.395488e-01 20 35741941 35742113 173 - 1.878 1.793 -0.285
ENSG00000131051 E087 38.0159649 0.0095300050 7.742545e-01 9.132894e-01 20 35742114 35742244 131 - 1.567 1.586 0.064
ENSG00000131051 E088 2.9745538 0.0072710715 5.286134e-01 7.802047e-01 20 35742245 35742312 68 - 0.533 0.621 0.396

Help

Please Click HERE to learn more details about the results from DEXseq.